Spontaneous NF-κB Activation by Autocrine TNFα Signaling: A Computational Analysis
Figure 8
Fraction of responding cells versus TNFαdose.
(A) Tonic stimulation. (B) 5-min pulsed stimulation. Color bars: model prediction for = 0.025– fraction of cells responding within the given time period. Error bars show fractions of cells responding during the first 300-min in the experiment of Turner et al. [75] on SK-N-AS cells, see the main text.