Transcriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils
Figure 5
Analysis of pathways and gene groups using Genomica, comparing tumor associated neutrophils (TAN) to the granulocytic fraction of myeloid derived suppressor cells (G-MDSC).
Each sample was evaluated for changes in the different pathways, and was marked as positive when ≥3 genes were significantly changed to the same direction. In each panel - Right - Pathways/Groups that had more than 5 samples changed. Left - Pathways/Groups that were significantly changed when the groups were compared to each other (p<0.05, corrected). Red – up-regulation; Blue – down-regulation; Black – no change from mean.