Diosgenin, a Steroidal Saponin, Inhibits Migration and Invasion of Human Prostate Cancer PC-3 Cells by Reducing Matrix Metalloproteinases Expression
Figure 6
Effects of diosgenin on phosphorylation of PI3K and Akt.
PC-3 cells were treated with various doses of diosgenin for 24 h (A), or 20 µM of diosgenin for 3, 6, 12, 18 and 24 h (B). The phosphorylation of PI3K and Akt was determined by SDS-PAGE and Western blotting. β-actin was used as a loading control.