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JKAMP

S Wikipedije, slobodne enciklopedije
JKAMP
Identifikatori
AliasiJKAMP
Vanjski ID-jeviOMIM: 611176 MGI: 1915057 HomoloGene: 9524 GeneCards: JKAMP
Lokacija gena (čovjek)
Hromosom 14 (čovjek)
Hrom.Hromosom 14 (čovjek)[1]
Hromosom 14 (čovjek)
Genomska lokacija za JKAMP
Genomska lokacija za JKAMP
Bend14q23.1Početak59,484,443 bp[1]
Kraj59,505,410 bp[1]
Lokacija gena (miš)
Hromosom 12 (miš)
Hrom.Hromosom 12 (miš)[2]
Hromosom 12 (miš)
Genomska lokacija za JKAMP
Genomska lokacija za JKAMP
Bend12|12 C3Početak72,132,363 bp[2]
Kraj72,148,235 bp[2]
Ontologija gena
Molekularna funkcija ubiquitin protein ligase binding
Ćelijska komponenta integral component of membrane
endoplasmic reticulum membrane
Endoplazmatski retikulum
membrana
Biološki proces response to unfolded protein
ubiquitin-dependent ERAD pathway
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)
NM_001098625
NM_001284201
NM_001284202
NM_001284203
NM_001284204

NM_016475

NM_001205067
NM_024205

RefSeq (bjelančevina)
NP_001092095
NP_001271130
NP_001271131
NP_001271132
NP_001271133

NP_057559
NP_001271130.1

NP_001191996
NP_077167

Lokacija (UCSC)Chr 14: 59.48 – 59.51 MbChr 12: 72.13 – 72.15 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

JNK1-pridruženi membranski protein je protein kji je kod ljudi kodiran genom JKAMP.[5][6][7]

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 326 aminokiselina, a molekulska težina 36.751 Da.[8].

Simboli
1020304050
MFGAAARSADLALLEKNLQAAHGCLGLYCGKTLLFKNGSTEIYGECGVCP
RGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSS
SALFQHITALFECSMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNP
SPDYVTTVHCTHEAVYPLYTIVFIYYAFCLVLMMLLRPLLVKKIACGLGK
SDRFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSA
SEIENCYDLLVRKKRLIVLFSHWLLHAYGIISISRVDKLEQDLPLLALVP
TPALFYLFTAKFTEPSRILSEGANGH

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000050130 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000005078 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kadoya T, Khurana A, Tcherpakov M, Bromberg KD, Didier C, Broday L, Asahara T, Bhoumik A, Ronai Z (Sep 2005). "JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity". Mol Cell Biol. 25 (19): 8619–30. doi:10.1128/MCB.25.19.8619-8630.2005. PMC 1265750. PMID 16166642.
  6. ^ Tcherpakov M, Delaunay A, Toth J, Kadoya T, Petroski MD, Ronai ZA (Apr 2009). "Regulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP)". J Biol Chem. 284 (18): 12099–109. doi:10.1074/jbc.M808222200. PMC 2673279. PMID 19269966.
  7. ^ "Entrez Gene: C14orf100 chromosome 14 open reading frame 100".
  8. ^ "UniProt, Q9P055". Pristupljeno 26. 7. 2021.

Dopunska literatura

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