Pages that link to "Q24313595"

The following pages link to Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4 (Q24313595):

Displayed 50 items.

• LYN proto-oncogene, Src family tyrosine kinase (Q2463389) ‎ (← links)
• HCK proto-oncogene, Src family tyrosine kinase (Q21113798) ‎ (← links)
• Identification and cloning of a novel cellular protein Naf1, Nef-associated factor 1, that increases cell surface CD4 expression (Q22008728) ‎ (← links)
• NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling (Q22009551) ‎ (← links)
• Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions (Q22010220) ‎ (← links)
• Identification of the Nef-associated kinase as p21-activated kinase 2 (Q22010961) ‎ (← links)
• HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes (Q22253302) ‎ (← links)
• Rack1 binds HIV-1 Nef and can act as a Nef-protein kinase C adaptor (Q24291151) ‎ (← links)
• Further studies on hepatitis C virus NS5A-SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling (Q24298665) ‎ (← links)
• Binding of cellular p32 protein to the rubella virus P150 replicase protein via PxxPxR motifs (Q24301681) ‎ (← links)
• Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse (Q24309257) ‎ (← links)
• A novel acyl-CoA thioesterase enhances its enzymatic activity by direct binding with HIV Nef (Q24312555) ‎ (← links)
• The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity (Q24313430) ‎ (← links)
• A Ras-GTPase-activating protein SH3-domain-binding protein (Q24316153) ‎ (← links)
• Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activity (Q24320192) ‎ (← links)
• Binding of HIV-1 Nef to a novel thioesterase enzyme correlates with Nef-mediated CD4 down-regulation (Q24321956) ‎ (← links)
• The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling (Q24322710) ‎ (← links)
• Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4 (Q24323265) ‎ (← links)
• The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules (Q24323939) ‎ (← links)
• Binding of c-Raf1 kinase to a conserved acidic sequence within the carboxyl-terminal region of the HIV-1 Nef protein (Q24324674) ‎ (← links)
• Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain (Q24336554) ‎ (← links)
• Myristoyl moiety of HIV Nef is involved in regulation of the interaction with calmodulin in vivo (Q24337512) ‎ (← links)
• HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation (Q24338895) ‎ (← links)
• Structure--function relationships in HIV-1 Nef. (Q24522550) ‎ (← links)
• Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions (Q24524045) ‎ (← links)
• Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex (Q24527321) ‎ (← links)
• Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling (Q24532104) ‎ (← links)
• Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation (Q24532862) ‎ (← links)
• A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein (Q24598018) ‎ (← links)
• The Nef protein of HIV-1 associates with rafts and primes T cells for activation (Q24645110) ‎ (← links)
• HIV-1 Nef-induced FasL induction and bystander killing requires p38 MAPK activation (Q24669980) ‎ (← links)
• The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix (Q24673997) ‎ (← links)
• Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain (Q24676619) ‎ (← links)
• Nef-mediated clathrin-coated pit formation (Q24678715) ‎ (← links)
• SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55 (Q24678799) ‎ (← links)
• Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity (Q24682806) ‎ (← links)
• HIV Genome-Wide Protein Associations: a Review of 30 Years of Research (Q26746070) ‎ (← links)
• Remodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and Persistence (Q26767362) ‎ (← links)
• Small molecule inhibitors of the HIV-1 virulence factor, Nef (Q27013915) ‎ (← links)
• Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence (Q27489673) ‎ (← links)
• Molecular basis for the binding of SH3 ligands with non-peptide elements identified by combinatorial synthesis (Q27733423) ‎ (← links)
• beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis (Q28141212) ‎ (← links)
• HIV-1 Nef control of cell signalling molecules: multiple strategies to promote virus replication (Q28202882) ‎ (← links)
• Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators (Q28203103) ‎ (← links)
• A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor (Q28288514) ‎ (← links)
• The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement (Q28477983) ‎ (← links)
• The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase (Q28647550) ‎ (← links)
• HIV-1 nef protein structures associated with brain infection and dementia pathogenesis (Q28742931) ‎ (← links)
• Modular binding domains in signal transduction proteins (Q29617351) ‎ (← links)
• Hydrogen Exchange Mass Spectrometry of Related Proteins with Divergent Sequences: A Comparative Study of HIV-1 Nef Allelic Variants (Q30008993) ‎ (← links)