Ginsenoside Rk1 is a novel inhibitor of NMDA receptors in cultured rat hippocampal neurons (Q94560481)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32372871%20AND%20SRC:MED&resulttype=core&format=json

15 May 2020

title

Ginsenoside Rk1 is a novel inhibitor of NMDA receptors in cultured rat hippocampal neurons (English)

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15 May 2020

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15 May 2020

Nayeon Ryoo

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15 May 2020

Hongik Hwang

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15 May 2020

Sung Kwon Ko

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15 May 2020

Seung-Yeol Nah

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15 May 2020

Hyoung-Chun Kim

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15 May 2020

Hyewhon Rhim

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15 May 2020

publication date

13 April 2019

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Journal of Ginseng Research

15 May 2020

published in

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15 May 2020

volume

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15 May 2020

issue

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15 May 2020

page(s)

490-495

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Traumatic brain injury: a risk factor for neurodegenerative diseases.

15 May 2020

cites work

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Rk1, a ginsenoside, is a new blocker of vascular leakage acting through actin structure remodeling

11 February 2021

1 reference

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Ginsenosides from American ginseng: chemical and pharmacological diversity

11 February 2021

1 reference

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Ginsenosides and their CNS targets.

11 February 2021

1 reference

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Ginsenoside Rb1 regulates the expressions of brain-derived neurotrophic factor and caspase-3 and induces neurogenesis in rats with experimental cerebral ischemia

11 February 2021

1 reference

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Ginsenoside Rg1 promotes peripheral nerve regeneration in rat model of nerve crush injury

11 February 2021

1 reference

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Ginseng compounds: an update on their molecular mechanisms and medical applications

11 February 2021

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Current evaluation of the millennium phytomedicine--ginseng (I): etymology, pharmacognosy, phytochemistry, market and regulations

11 February 2021

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20(S)-ginsenoside Rg3, a neuroprotective agent, inhibits mitochondrial permeability transition pores in rat brain

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7195591

Rg1 reduces nigral iron levels of MPTP-treated C57BL6 mice by regulating certain iron transport proteins

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7195591

A NMDA receptor glycine site partial agonist, GLYX-13, simultaneously enhances LTP and reduces LTD at Schaffer collateral-CA1 synapses in hippocampus

11 February 2021

1 reference

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Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7195591

Ginsenoside Rg1 restores the impairment of learning induced by chronic morphine administration in rats

11 February 2021

1 reference

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Ginsenosides: are any of them candidates for drugs acting on the central nervous system?

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7195591

NMDA receptor and iNOS are involved in the effects of ginsenoside Rg1 on hippocampal neurogenesis in ischemic gerbils

11 February 2021

1 reference

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20(S)-ginsenoside Rh2, a newly identified active ingredient of ginseng, inhibits NMDA receptors in cultured rat hippocampal neurons

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7195591

Memory enhancing and neuroprotective effects of selected ginsenosides

11 February 2021

1 reference

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Ginsenoside Rg3 antagonizes NMDA receptors through a glycine modulatory site in rat cultured hippocampal neurons

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7195591

Ginsenosides Rb1 and Rg1 effects on mesencephalic dopaminergic cells stressed with glutamate

11 February 2021

1 reference

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Three new dammarane glycosides from heat processed ginseng

11 February 2021

1 reference

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Inhibitory effect of ginsenosides on NMDA receptor-mediated signals in rat hippocampal neurons

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7195591

Protective effect of ginsenosides, active ingredients of Panax ginseng, on kainic acid-induced neurotoxicity in rat hippocampus

11 February 2021

1 reference

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Neuroprotective effects of ginseng total saponin and ginsenosides Rb1 and Rg1 on spinal cord neurons in vitro

11 February 2021

1 reference

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Liquid chromatographic determination of less polar ginsenosides in processed ginseng

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7195591

Subunit- and site-specific pharmacology of the NMDA receptor channel

11 February 2021

1 reference

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The changing landscape of ischaemic brain injury mechanisms.

11 February 2021

1 reference

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Ginsenosides Rb1 and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration

11 February 2021

1 reference

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Kainate receptors: an interplay between excitatory and inhibitory synapses

11 February 2021

1 reference

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Synthesis and structure-activity studies of N,N'-diarylguanidine derivatives. N-(1-naphthyl)-N'-(3-ethylphenyl)-N'-methylguanidine: a new, selective noncompetitive NMDA receptor antagonist

11 February 2021

1 reference

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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7195591

10.1016/J.JGR.2019.04.002

11 February 2021

Identifiers

DOI

1 reference

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15 May 2020

1 reference

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15 May 2020

PubMed publication ID

32372871

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