KIT proto-oncogene, receptor tyrosine kinase (Q909409)

Protein kinase-like domain superfamily

1 reference

Immunoglobulin-like domain superfamily

1 reference

Mast/stem cell growth factor receptor

1 reference

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

Immunoglobulin subtype, protein family

1 reference

Immunoglobulin subtype 2, protein family

1 reference

Protein kinase domain, protein family

1 reference

immunoglobulin-like domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, receptor class III, conserved site, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

Immunoglobulin domain, protein family

1 reference

stem cell factor receptor activity

1 reference

13 November 2019

0 references

1 reference

13 November 2019

0 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

1 reference

8 April 2019

transmembrane receptor protein tyrosine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

27 March 2018

27 March 2018

Mechanism of activation of human c-KIT kinase by internal tandem duplications of the juxtamembrane domain and point mutations at aspartic acid 816

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

protein kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

1 reference

8 April 2019

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

1 reference

8 April 2019

transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

1 reference

8 April 2019

protein homodimerization activity

1 reference

8 April 2019

Mechanism of activation of human c-KIT kinase by internal tandem duplications of the juxtamembrane domain and point mutations at aspartic acid 816

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

protease binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

protein binding

10 references

8 April 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

The direct association of the multiple PDZ domain containing proteins (MUPP-1) with the human c-Kit C-terminus is regulated by tyrosine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

The receptor protein tyrosine phosphatase, PTP-RO, is upregulated during megakaryocyte differentiation and Is associated with the c-Kit receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

Formation of signal transfer complexes between stem cell and platelet-derived growth factor receptors and SH2 domain proteins in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

The ubiquitously expressed Syp phosphatase interacts with c-kit and Grb2 in hematopoietic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

Inhibition of SH2 domain/phosphoprotein association by a nonhydrolyzable phosphonopeptide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

Identification of Tyr900 in the kinase domain of c-Kit as a Src-dependent phosphorylation site mediating interaction with c-Crk

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

protein tyrosine kinase activity

Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

1 reference

8 April 2019

phosphatidylinositol-4,5-bisphosphate 3-kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

1 reference

1 January 2018

receptor tyrosine kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

10 September 2018

10 September 2018

Mechanism of activation of human c-KIT kinase by internal tandem duplications of the juxtamembrane domain and point mutations at aspartic acid 816

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

transmembrane signaling receptor activity

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

transmembrane receptor protein tyrosine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

8 April 2019

Mechanism of activation of human c-KIT kinase by internal tandem duplications of the juxtamembrane domain and point mutations at aspartic acid 816

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

SH2 domain binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

cell component

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

1 reference

8 April 2019

cell-cell junction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

cytoplasmic side of plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

cell surface

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

integral component of membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

1 reference

8 April 2019

acrosomal vesicle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

external side of plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

mast cell granule

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

extracellular space

1 reference

8 April 2019

Tumor necrosis factor-alpha-converting enzyme controls surface expression of c-Kit and survival of embryonic stem cell-derived mast cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

3 references

10 September 2018

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

integral component of plasma membrane

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

receptor complex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

myeloid progenitor cell differentiation

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of MAP kinase activity

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

glycosphingolipid metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of phospholipase C activity

1 reference

8 April 2019

Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

hematopoietic stem cell migration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

stem cell population maintenance

1 reference

8 April 2019

Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

spermatogenesis

Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

cell chemotaxis

1 reference

8 April 2019

Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

developmental pigmentation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

melanocyte differentiation

Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of Notch signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

transmembrane receptor protein tyrosine kinase signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

1 reference

10 September 2018

lymphoid progenitor cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

spermatid development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

negative regulation of programmed cell death

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

mast cell degranulation

1 reference

8 April 2019

CD72 negatively regulates KIT-mediated responses in human mast cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of MAPK cascade

1 reference

10 September 2018

Mechanism of activation of human c-KIT kinase by internal tandem duplications of the juxtamembrane domain and point mutations at aspartic acid 816

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

myeloid leukocyte differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

male gonad development

IEP

1 reference

8 April 2019

Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimester

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

IEP

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

1 reference

8 April 2019

positive regulation of DNA-binding transcription factor activity

1 reference

8 April 2019

Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

epithelial cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

ectopic germ cell programmed cell death

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

response to radiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

mast cell cytokine production

1 reference

8 April 2019

CD72 negatively regulates KIT-mediated responses in human mast cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of receptor signaling pathway via JAK-STAT

1 reference

10 September 2018

Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

visual learning

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

actin cytoskeleton reorganization

1 reference

8 April 2019

Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

intracellular signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

somatic stem cell population maintenance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of cell migration

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

somatic stem cell division

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

mast cell chemotaxis

1 reference

8 April 2019

CD72 negatively regulates KIT-mediated responses in human mast cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

MAPK cascade

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

1 reference

8 April 2019

positive regulation of phosphatidylinositol 3-kinase activity

1 reference

8 April 2019

Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of pseudopodium assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of gene expression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of long-term neuronal synaptic plasticity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

regulation of cell population proliferation

cellular response to thyroid hormone stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of cell population proliferation

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

regulation of developmental pigmentation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

8 April 2019

Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

mast cell differentiation

Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

germ cell migration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

signal transduction

1 reference

8 April 2019

Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

mast cell proliferation

1 reference

8 April 2019

Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of vascular associated smooth muscle cell differentiation

1 reference

8 April 2019

Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

phosphatidylinositol phosphate biosynthetic process

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

regulation of transcription by RNA polymerase II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

1 reference

8 April 2019

positive regulation of tyrosine phosphorylation of STAT protein

1 reference

8 April 2019

Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

tongue development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

response to cadmium ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of pyloric antrum smooth muscle contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

regulation of bile acid metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of small intestine smooth muscle contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of colon smooth muscle contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of protein kinase B signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

1 reference

8 April 2019

negative regulation of signal transduction

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

cell differentiation

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

negative regulation of apoptotic process

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P10721&geneProductId=UniProtKB:P10721

positive regulation of ERK1 and ERK2 cascade

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

hematopoietic progenitor cell differentiation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

B cell differentiation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

Kit signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

3 references

8 April 2019

8 April 2019

Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10721

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via JAK-STAT

physically interacts with

1 reference

5664

17 August 2016

1 reference

7882

17 August 2016

1 reference

5657

17 August 2016

1 reference

5656

17 August 2016

1 reference

5698

17 August 2016

1 reference

5056

17 August 2016

1 reference

5711

17 August 2016

1 reference

5713

English

17 August 2016

imatinib

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL941

masitinib

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1908391

amuvatinib

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2103851

enmd-981693

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL482968

famitinib

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1278146

MLN-518

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL124660

imatinib mesylate

1 reference

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1642

has part(s)

immunoglobulin domain

1 reference

immunoglobulin subtype 2

1 reference

tyrosine-protein kinase, active site

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference

immunoglobulin-like domain

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

tyrosine-protein kinase, receptor class III, conserved site

1 reference

immunoglobulin subtype

1 reference

D08.811.913.696.620.682.725.400.050

Identifiers

MeSH descriptor ID

D019009

subject named as

Proto-Oncogene Proteins c-kit

0 references

MeSH tree code

0 references

D12.776.543.750.630.124

0 references

D12.776.543.750.705.852.150.100

0 references

D12.776.543.750.750.400.200.170

0 references

D12.776.624.664.700.183

0 references

D12.776.476.568.400.050

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference

UMLS 2023