cabozantinib (Q795057)

Cabozantinib (English)

3 October 2016

chemical formula

C₂₈H₂₄FN₃O₅

1 reference

Cabozantinib (English)

19 November 2016

canonical SMILES

COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F

1 reference

Cabozantinib (English)

European Medicines Agency product number

19 November 2016

active ingredient in

Cometriq

1 reference

EMEA/H/C/002640

reference URL

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/002640/human_med_001726.jsp

22 March 2017

1 reference

14 February 2018

medical condition treated

kidney cancer

1 reference

2 October 2018

Tuberculosis (possibly)

1 reference

2 October 2018

renal cell carcinoma

1 reference

2 October 2018

renal pelvis carcinoma

1 reference

imported from Wikimedia project

2 October 2018

pregnancy category

US pregnancy category D

1 reference

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category E*

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Cabozantinib

last update

4 January 2017

subject has role

protein kinase inhibitors

1 reference

5 March 2018

0 references

Identifiers

InChI

InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34)

1 reference

Cabozantinib (English)

19 November 2016

2 references

Cabozantinib (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

849217-68-1

2 references

cabozantinib (English)

19 November 2016

https://commonchemistry.cas.org/detail?cas_rn=849217-68-1

9 April 2021

1 reference

Cabozantinib (English)

19 November 2016

1 reference

Cabozantinib (English)

19 November 2016

Reaxys registry number

18631644

1 reference

cabozantinib (English)

3 October 2016

ChEBI ID

72317

mapping relation type

2 references

CABOZANTINIB (English)

19 November 2016

International Chemical Identifier

InChI

InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34)

1 reference

CABOZANTINIB (English)

19 November 2016

2 references

inferred from InChIKey

splash10-0udi-0139180000-20096332e7e989d72392

1 reference

0 references

DSSTox substance ID

DTXSID10233968

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.221.147

27 December 2018

ECHA Substance Infocard ID

[No public or meaningful name is available] (English)

quotation

CAS no.: 849217-68-1 (English)

100.221.147

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.221.147

27 December 2018

[No public or meaningful name is available] (English)

quotation

CAS no.: 849217-68-1 (English)

1 reference

Guide to Pharmacology Ligand ID

Cabozantinib (English)

publication date

17 November 2015

5887

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5887

cabozantinib (English)

19 November 2016

1 reference

cabozantinib (English)

19 November 2016

DrugBank ID

DB08875

1 reference

Human Metabolome Database ID

HMDB0249524

2 references

based on heuristic

inferred from InChIKey

2 references

cabozantinib (English)

19 November 2016

MedlinePlus drug identifier

0 references

1 reference

cabozantinib (English)

19 November 2016

0 references

1 reference

1 reference

cabozantinib (English)

https://docs.openalex.org/download-snapshot/snapshot-data-format

3 October 2016

Freebase ID

/m/0gtvzpd

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

ScienceDirect topic ID

biochemistry-genetics-and-molecular-biology/cabozantinib

0 references

UMLS CUI

C3181682

1 reference

cabozantinib (English)