Bcl-2 and Bax proteins are present in interphase nuclei of mammalian cells (Q73694637)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773823%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Bcl-2 and Bax proteins are present in interphase nuclei of mammalian cells (English)

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6 November 2019

Hoetelmans R

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6 November 2019

van Slooten HJ

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6 November 2019

Keijzer R

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6 November 2019

Erkeland S

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6 November 2019

van de Velde CJ

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6 November 2019

Dierendonck JH

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6 November 2019

publication date

1 April 2000

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Cell Death & Differentiation

6 November 2019

published in

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6 November 2019

volume

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6 November 2019

issue

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6 November 2019

page(s)

384-392

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The Bcl-2 protein family: arbiters of cell survival

6 November 2019

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Bcl-2 family proteins

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Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

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Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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Bcl-2 and Bax function independently to regulate cell death

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Overexpressed full-length human BCL2 extends the survival of baculovirus-infected Sf9 insect cells

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Ultrastructural localization of bcl-2 protein

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Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA.

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The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation

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7 January 2021

The protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosis

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Altered sensitivity to retinoid-induced apoptosis associated with changes in the subcellular distribution of Bcl-2.

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Movement of Bax from the Cytosol to Mitochondria during Apoptosis

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

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Regulated targeting of BAX to mitochondria.

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Nuclear targeting of Bax during apoptosis in human colorectal cancer cells

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Nuclear translocation and increased expression of Bax and disturbance in cell cycle progression without prominent apoptosis induced by hyperthermia

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7 January 2021

Induction of Bax protein and degradation of lamin A during p53-dependent apoptosis induced by chemotherapeutic agents in human cancer cell lines

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7 January 2021

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

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7 January 2021

Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2

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7 January 2021

Inhibition of Bax channel-forming activity by Bcl-2

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7 January 2021

Expression of Bcl-2 in node-negative breast cancer is associated with various prognostic factors, but does not predict response to one course of perioperative chemotherapy

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7 January 2021

Transient mitotic phase localization of bcl-2 oncoprotein in human carcinoma cells and its possible role in prevention of apoptosis

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Nuclear and cytoplasmic bcl-2 expression in endometrial hyperplasia and adenocarcinoma

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Expression of bcl-2 oncoprotein in renal cell tumours

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7 January 2021

Nuclear bcl-2 Staining in Tumors

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7 January 2021

Mitotic chromosomal bcl-2. I. Stable expression throughout the cell cycle and association with isolated chromosomes.

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7 January 2021

Mitotic chromosomal bcl-2. II. Localization to interphase nuclei

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7 January 2021

Colocalization of emerin and lamins in interphase nuclei and changes during mitosis

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7 January 2021

Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.

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7 January 2021

Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest

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7 January 2021

PML induces a novel caspase-independent death process

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7 January 2021

The E1B 19K protein associates with lamins in vivo and its proper localization is required for inhibition of apoptosis.

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7 January 2021

Loss of Bcl-2 in invasive breast cancer is associated with high rates of cell death, but also with increased proliferative activity

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7 January 2021

The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

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7 January 2021

A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis.

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7 January 2021

An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators

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7 January 2021

Targeted neutralization of calmodulin in the nucleus blocks DNA synthesis and cell cycle progression

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7 January 2021

Chapter 4 Preparation of Isolated Rat Liver Cells

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4400664

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773823%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

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