Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo (Q73263520)

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2 November 2019

title

Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo (English)

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2 November 2019

Rafi Ahmed

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2 November 2019

E John Wherry

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2 November 2019

Joseph N Blattman

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2 November 2019

Jason M Grayson

series ordinal

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2 November 2019

Susan M Kaech

series ordinal

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2 November 2019

Kendall A Smith

series ordinal

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2 November 2019

publication date

14 April 2003

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2 November 2019

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2 November 2019

volume

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2 November 2019

issue

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2 November 2019

page(s)

540-547

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Interleukin-2: inception, impact, and implications

2 November 2019

cites work

1 reference

7 January 2021

The detection of a spleen focus-forming virus neoantigen by lymphocyte-mediated cytolysis

1 reference

7 January 2021

Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death

1 reference

7 January 2021

Long term culture of tumour-specific cytotoxic T cells

1 reference

7 January 2021

Interleukin-2 receptor common gamma-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: selective induction of anti-apoptotic (bcl-2, bcl-xL) but not pro-apoptotic (bax, bcl-xS) gene expression

1 reference

7 January 2021

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

1 reference

7 January 2021

Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/Ig plasmid administration in rhesus monkeys

1 reference

7 January 2021

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

1 reference

7 January 2021

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

1 reference

7 January 2021

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

1 reference

7 January 2021

The dual role of IL-2 in the generation and maintenance of CD8+ memory T cells

1 reference

7 January 2021

Control of homeostasis of CD8+ memory T cells by opposing cytokines.

1 reference

7 January 2021

Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer

1 reference

7 January 2021

Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus

1 reference

7 January 2021

Interleukin-2 induced immune effects in human immunodeficiency virus-infected patients receiving intermittent interleukin-2 immunotherapy

1 reference

7 January 2021

Immunologic and virologic effects of subcutaneous interleukin 2 in combination with antiretroviral therapy: A randomized controlled trial

1 reference

7 January 2021

Rational interleukin 2 therapy for HIV positive individuals: daily low doses enhance immune function without toxicity

1 reference

7 January 2021

Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

1 reference

7 January 2021

Viral immune evasion due to persistence of activated T cells without effector function

1 reference

7 January 2021

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

1 reference

7 January 2021

Cutting edge: antigen-independent CD8 T cell proliferation.

1 reference

7 January 2021

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

1 reference

7 January 2021

CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge.

1 reference

7 January 2021

Cytotoxic T-cell memory without antigen

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7 January 2021

Gene expression in antigen-specific CD8+ T cells during viral infection

1 reference

7 January 2021

Cutting edge: naive T cells masquerading as memory cells

1 reference

7 January 2021

Clinical effects and toxicity of interleukin-2 in patients with cancer

1 reference

7 January 2021

Induction of circulating tumor necrosis factor (TNF alpha) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients

1 reference

7 January 2021

Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus In vivo

1 reference

7 January 2021

Direct visualization of HIV-1-specific cytotoxic T lymphocytes during primary infection.

1 reference

7 January 2021

High Frequency of Cytomegalovirus‐Specific Cytotoxic T‐Effector Cells in HLA‐A*0201–Positive Subjects during Multiple Viral Coinfections

1 reference

7 January 2021

Direct measurement of CD4+ and CD8+ T-cell responses to CMV in HIV-1-infected subjects.

1 reference

7 January 2021

Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

1 reference

7 January 2021

To cure chronic HIV infection, a new therapeutic strategy is needed

1 reference

7 January 2021

Prospects for adoptive T cell therapy

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7 January 2021

Identifiers

DOI

10.1038/NM866

1 reference

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2 November 2019

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