Possible involvement of multiple P-glycoprotein-mediated efflux systems in the transport of verapamil and other organic cations across rat intestine (Q70922425)

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scientific article published on 01 September 1995

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English	Possible involvement of multiple P-glycoprotein-mediated efflux systems in the transport of verapamil and other organic cations across rat intestine	scientific article published on 01 September 1995

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8570526%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

Possible involvement of multiple P-glycoprotein-mediated efflux systems in the transport of verapamil and other organic cations across rat intestine (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8570526%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

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author name string

H Saitoh

1

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14 October 2019

B J Aungst

2

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14 October 2019

publication date

1 September 1995

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14 October 2019

Pharmaceutical Research

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14 October 2019

12

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14 October 2019

9

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14 October 2019

1304-1310

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14 October 2019

In Vitro Drug Absorption Models. II. Salicylate, Cefoxitin, α-Methyldopa and Theophylline Uptake in Cells and Rings: Correlation with In Vivo Bioavailability

1 reference

https://pubmed.ncbi.nlm.nih.gov/8570526

12 December 2020

based on heuristic

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Clinical trials of agents that reverse multidrug resistance. A literature review

1 reference

https://pubmed.ncbi.nlm.nih.gov/8570526

12 December 2020

based on heuristic

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Evidence for a polarized efflux system in CACO-2 cells capable of modulating cyclosporin A transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/8570526

12 December 2020

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Binding of organic cations to brush border membrane from rat small intestine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8570526

12 December 2020

based on heuristic

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The function of Gp170, the multidrug-resistance gene product, in the brush border of rat intestinal mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/8570526

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Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals

1 reference

https://pubmed.ncbi.nlm.nih.gov/8570526

12 December 2020

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Pharmacodynamic profile of verapamil in relation to absolute bioavailability: investigations with a conventional and a controlled-release formulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8570526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caco-2 cell monolayers as a model for drug transport across the intestinal mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/8570526

12 December 2020

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Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators

1 reference

https://pubmed.ncbi.nlm.nih.gov/8570526

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P-glycoproteins: mediators of multidrug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/8570526

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Effect of chlorpromazine on the permeability of beta-lactam antibiotics across rat intestinal brush border membrane vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/8570526

12 December 2020

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Assessment of bioavailability of experimental single-unit sustained release tablets of verapamil hydrochloride using the stable isotope technique

1 reference

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based on heuristic

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Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/8570526

12 December 2020

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Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells

1 reference

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ATP-dependent transport of amphiphilic cations across the hepatocyte canalicular membrane mediated by mdr1 P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/8570526

12 December 2020

based on heuristic

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Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers

1 reference

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Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil

1 reference

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Pharmacology of drugs that alter multidrug resistance in cancer

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Interaction between intestinal absorption and secretion of monoquaternary ammonium compounds in guinea pigs--a concept for the absorption kinetics of organic cations.

1 reference

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12 December 2020

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Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells.

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Verapamil. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension

1 reference

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The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues

1 reference

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Contribution of passive transport mechanisms to the intestinal absorption of beta-lactam antibiotics

1 reference

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P-glycoprotein and organic cation secretion by the mammalian kidney

1 reference

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Transport of guanidine in rabbit intestinal brush-border membrane vesicles

1 reference

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12 December 2020

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Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

1 reference

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12 December 2020

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A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

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Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein

1 reference

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12 December 2020

based on heuristic

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Evidence for a polarized efflux system for peptides in the apical membrane of Caco-2 cells

1 reference

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12 December 2020

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In vitro measurement of gastrointestinal tissue permeability using a new diffusion cell.

1 reference

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Identifiers

10.1023/A:1016217505990

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8570526%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8570526%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

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