Protein folding (Q68539600)

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25 September 2019

review article

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title

Protein folding (English)

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25 September 2019

T E Creighton

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25 September 2019

publication date

1 August 1990

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25 September 2019

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25 September 2019

volume

270

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25 September 2019

issue

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25 September 2019

page(s)

1-16

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Nucleation, rapid folding, and globular intrachain regions in proteins

25 September 2019

cites work

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12 December 2020

The equilibrium unfolding parameters of horse and sperm whale myoglobin. Effects of guanidine hydrochloride, urea, and acid

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12 December 2020

Principles that govern the folding of protein chains

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12 December 2020

Intermediates in Protein Folding Reactions and the Mechanism of Protein Folding

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12 December 2020

Electrophoretic study of reversible protein denaturation. Chymotrypsinogen at high pressures

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12 December 2020

Consideration of the possibility that the slow step in protein denaturation reactions is due to cis-trans isomerism of proline residues

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12 December 2020

Reactivities of the cysteine residues of the reduced pancreatic trypsin inhibitor

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12 December 2020

Thermodynamic investigations of proteins. III. Thermodynamic description of lysozyme

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12 December 2020

Structural patterns in globular proteins

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12 December 2020

Guanidine-unfolded state of ribonuclease A contains both fast- and slow-refolding species

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12 December 2020

Effects of urea and guanidine-HCl on the folding and unfolding of pancreatic trypsin inhibitor

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12 December 2020

Heat capacity and entropy changes in processes involving proteins

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12 December 2020

Thermal unfolding transition of ribonuclease A measured by 2'-CMP binding

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12 December 2020

Stability of protein conformation: internal packing and enthalpy of fusion of model compounds

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12 December 2020

Unfolding and refolding occur much faster for a proline-free proteins than for most proline-containing proteins

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12 December 2020

Immunochemical analysis of the conformational properties of intermediates trapped in the folding and unfolding of bovine pancreatic trypsin inhibitor

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12 December 2020

Experimental studies of protein folding and unfolding

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12 December 2020

Expression of functionality of alpha-chymotrypsin. Effects of guanidine hydrochloride and urea in the onset of denaturation

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12 December 2020

Possible implications of many proline residues for the kinetics of protein unfolding and refolding

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12 December 2020

Kinetics of the helix-coil transition of a polypeptide with non-ionic side groups, derived from ultrasonic relaxation measurements

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12 December 2020

Detection of an early intermediate in the folding of ribonuclease A by protection of amide protons against exchange

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12 December 2020

Kinetic study of protein unfolding and refolding using urea gradient electrophoresis

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12 December 2020

Stability of proteins: small globular proteins

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12 December 2020

Ultraviolet difference spectroscopy of intermediates trapped in unfolding and refolding of bovine pancreatic trypsin inhibitor

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12 December 2020

Catalysis by protein-disulphide isomerase of the unfolding and refolding of proteins with disulphide bonds

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12 December 2020

Spectral evidence for a rapidly formed structural intermediate in the refolding kinetics of hen egg-white lysozyme

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12 December 2020

Formation of the intrachain disulfide bond in the constant fragment of the immunoglobulin light chain

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12 December 2020

Circular dichroism spectroscopy of bovine pancreatic trypsin inhibitor and five altered conformational states. Relationship of conformation and the refolding pathway of the trypsin inhibitor

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12 December 2020

Accessibilities and reactivities of cysteine thiols during refolding of reduced bovine pancreatic trypsin inhibitor

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12 December 2020

Preliminary circular dichroism study of the conformations of intermediates trapped during protein folding

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12 December 2020

Is there a single pathway for the folding of a polypeptide chain?

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12 December 2020

Effect of side chain-backbone electrostatic interactions on the stability of alpha-helices

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12 December 2020

The study of conformational states of proteins by nuclear magnetic resonance

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12 December 2020

Specific intermediates in the folding reactions of small proteins and the mechanism of protein folding

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12 December 2020

Folding of ribonuclease A from a partially disordered conformation. Kinetic study under folding conditions.

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12 December 2020

Stability of proteins. Proteins which do not present a single cooperative system

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12 December 2020

Transmission of conformational change in insulin

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12 December 2020

Circular and circularly permuted forms of bovine pancreatic trypsin inhibitor

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12 December 2020

Circular dichroism spectroscopy of the intermediates that precede the rate-limiting step of the refolding pathway of bovine pancreatic trypsin inhibitor. Relationship of conformation and the refolding pathway

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12 December 2020

Characterization of the distribution of internal motions in the basic pancreatic trypsin inhibitor using a large number of internal NMR probes.

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12 December 2020

Evolutionary conservation and variation of protein folding pathways. Two protease inhibitor homologues from black mamba venom

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12 December 2020

An empirical approach to protein conformation stability and flexibility

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12 December 2020

Proton NMR studies of denatured lysozyme

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12 December 2020

The disulphide folding pathway of ribonuclease T1

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12 December 2020

Use of a trypsin-pulse method to study the refolding pathway of ribonuclease

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12 December 2020

Structural heterogeneity in protein crystals

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12 December 2020

Disulfide bonds as probes of protein folding pathways

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12 December 2020

Temperature dependence of the hydrophobic interaction in protein folding

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12 December 2020

Comparison between the unfolding rate and structural fluctuations in native lysozyme--effects of denaturants, ligand binding, and intrachain cross-linking on hydrogen exchange and unfolding kinetics

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12 December 2020

Cold denaturation of myoglobin

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12 December 2020

Folding/unfolding kinetics of mutant forms of iso-1-cytochrome c with replacement of proline-71

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12 December 2020

Evidence for identity between the equilibrium unfolding intermediate and a transient folding intermediate: a comparative study of the folding reactions of alpha-lactalbumin and lysozyme

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12 December 2020

Requirement of pro-sequence for the production of active subtilisin E in Escherichia coli

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12 December 2020

The thermodynamic stability of proteins

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12 December 2020

Rapid formation of secondary structure framework in protein folding studied by stopped-flow circular dichroism

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12 December 2020

Proline isomerism in staphylococcal nuclease characterized by NMR and site-directed mutagenesis

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12 December 2020

Catalysis of protein folding by prolyl isomerase

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12 December 2020

Temperature-sensitive mutations of bacteriophage T4 lysozyme occur at sites with low mobility and low solvent accessibility in the folded protein

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12 December 2020

Conformations of intermediates in the folding of the pancreatic trypsin inhibitor

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12 December 2020

Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme

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12 December 2020

Sequential mechanism of refolding of carbonic anhydrase B.

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12 December 2020

Activity change during unfolding of bovine pancreatic ribonuclease A in guanidine.

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12 December 2020

Protein stability curves

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12 December 2020

Replacement of proline-76 with alanine eliminates the slowest kinetic phase in thioredoxin folding

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12 December 2020

Genetic and structural analysis of the protein stability problem

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12 December 2020

Folding and association of proteins

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12 December 2020

Dissection of the structure and activity of the tyrosyl-tRNA synthetase by site-directed mutagenesis

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12 December 2020

Heat-shock proteins. Coming in from the cold.

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12 December 2020

Disulphide bonds and protein stability

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12 December 2020

Contribution of hydrophobic interactions to protein stability

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12 December 2020

Toward a better understanding of protein folding pathways

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12 December 2020

Genetic studies of protein stability and mechanisms of folding

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12 December 2020

Hydrophobic stabilization in T4 lysozyme determined directly by multiple substitutions of Ile 3

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12 December 2020

Characterization of a helical protein designed from first principles

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12 December 2020

Thermodynamic study of the apomyoglobin structure

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12 December 2020

NMR evidence for an early framework intermediate on the folding pathway of ribonuclease A

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12 December 2020

Structural characterization of folding intermediates in cytochrome c by H-exchange labelling and proton NMR.

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12 December 2020

A peptide model of a protein folding intermediate

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12 December 2020

Conformation of peptide fragments of proteins in aqueous solution: implications for initiation of protein folding

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12 December 2020

Protein structure determination in solution by nuclear magnetic resonance spectroscopy

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12 December 2020

Correct folding of circularly permuted variants of a beta alpha barrel enzyme in vivo

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12 December 2020

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

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12 December 2020

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

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12 December 2020

Conformational forces affecting the folding pathways of dendrotoxins I and K from black mamba venom

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12 December 2020

Nature and distribution of sites of temperature-sensitive folding mutations in the gene for the P22 tailspike polypeptide chain

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12 December 2020

Mutational analysis of a protein-folding pathway

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12 December 2020

Heat and cold denaturation of phosphoglycerate kinase (interaction of domains).

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12 December 2020

Analysis of prepro-alpha-lytic protease expression in Escherichia coli reveals that the pro region is required for activity

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12 December 2020

Unity in function in the absence of consensus in sequence: role of leader peptides in export

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12 December 2020

Separation of the nativelike intermediate from unfolded forms during refolding of ribonuclease A

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12 December 2020

On the relevance of non-random polypeptide conformations for protein folding

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12 December 2020

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12 December 2020

Formation of Randomly Paired Disulfide Bonds in Des-(121–124)-ribonuclease after Reduction and Reoxidation

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12 December 2020

Entropic Contributions to Rate Accelerations in Enzymic and Intramolecular Reactions and the Chelate Effect

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12 December 2020

Role of proline peptide bond isomerization in unfolding and refolding of ribonuclease

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12 December 2020

Proline isomerization during refolding of ribonuclease A is accelerated by the presence of folding intermediates

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12 December 2020

The relation between the divergence of sequence and structure in proteins

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12 December 2020

Immunological distinction between the possible origins of enzymatic activity in a polypeptide fragment of staphylococcal nuclease

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12 December 2020

The single-disulphide intermediates in the refolding of reduced pancreatic trypsin inhibitor

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12 December 2020

Experimental and Theoretical Aspects of Protein Folding

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12 December 2020

Probing the determinants of protein folding and stability with amino acid substitutions

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12 December 2020

Heat capacity and conformation of proteins in the denatured state

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12 December 2020

Proline isomerism leads to multiple folded conformations of calbindin D9k: direct evidence from two-dimensional 1H NMR spectroscopy

1 reference

12 December 2020

Interaction of cytidine 3'-monophosphate and uridine 3'-monophosphate with ribonuclease a at the denaturation temperature

1 reference

12 December 2020

A magnetization-transfer nuclear magnetic resonance study of the folding of staphylococcal nuclease

1 reference

12 December 2020

Characterization of a partly folded protein by NMR methods: studies on the molten globule state of guinea pig alpha-lactalbumin

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12 December 2020

Stability of protein structure and hydrophobic interaction.

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12 December 2020

Design of peptides and proteins

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12 December 2020

Low-temperature unfolding of a mutant of phage T4 lysozyme. 1. Equilibrium studies.

1 reference

12 December 2020

Low-temperature unfolding of a mutant of phage T4 lysozyme. 2. Kinetic investigations.

1 reference

12 December 2020

Residual structure in large fragments of staphylococcal nuclease: effects of amino acid substitutions.

1 reference

12 December 2020

Characterization of the critical state in protein folding. Effects of guanidine hydrochloride and specific Ca2+ binding on the folding kinetics of alpha-lactalbumin

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12 December 2020

Alternative packing arrangements in the hydrophobic core of λrepresser

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12 December 2020

Protein fragments as probes in the study of protein folding mechanisms: differential effects of dihydrofolate reductase fragments on the refolding of the intact protein

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12 December 2020

Effects of multiple replacements at a single position on the folding and stability of dihydrofolate reductase from Escherichia coli

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12 December 2020

Thermodynamic problems of protein structure.

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12 December 2020

The beta-sheet to coil transition

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12 December 2020

Protein disulfide isomerase: multiple roles in the modification of nascent secretory proteins

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12 December 2020

Mapping the transition state and pathway of protein folding by protein engineering

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12 December 2020

Further experimental studies of the disulfide folding transition of ribonuclease A

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12 December 2020

Unusually stable helix formation in short alanine-based peptides

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12 December 2020

Folding of a peptide corresponding to the alpha-helix in bovine pancreatic trypsin inhibitor

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12 December 2020

Energetics of complementary side-chain packing in a protein hydrophobic core

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12 December 2020

How does protein folding get started?

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12 December 2020

Mechanisms of cooperativity and allosteric regulation in proteins

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12 December 2020

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

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12 December 2020

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

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12 December 2020

Capping and alpha-helix stability

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12 December 2020

Hydrophobic effect in protein folding and other noncovalent processes involving proteins

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12 December 2020

Two types of rate-determining step in chemical and biochemical processes

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12 December 2020

A simple model for proteins with interacting domains. Applications to scanning calorimetry data

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12 December 2020

Theoretical study of the contribution of aromatic side chains to the circular dichroism of basic bovine pancreatic trypsin inhibitor

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12 December 2020

Common features of protein unfolding and dissolution of hydrophobic compounds

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12 December 2020

The unfolding and attempted refolding of mitochondrial aspartate aminotransferase from pig heart

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12 December 2020

The molten globule state as a clue for understanding the folding and cooperativity of globular-protein structure.

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12 December 2020

Protein sorting to mitochondria: evolutionary conservations of folding and assembly

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12 December 2020

The unfolding and attempted refolding of citrate synthase from pig heart

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12 December 2020

Relative helix-forming tendencies of nonpolar amino acids

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12 December 2020

Deciphering the message in protein sequences: tolerance to amino acid substitutions

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12 December 2020

Evidence for a molten globule state as a general intermediate in protein folding

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12 December 2020

Role of two proline-containing turns in the folding of porcine ribonuclease

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12 December 2020

Role of a subdomain in the folding of bovine pancreatic trypsin inhibitor

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12 December 2020

pH dependence of the urea and guanidine hydrochloride denaturation of ribonuclease A and ribonuclease T1.

1 reference

12 December 2020

Multiple replacements at position 211 in the alpha subunit of tryptophan synthase as a probe of the folding unit association reaction

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12 December 2020

The mechanism of protein folding. Implications of in vitro refolding models for de novo protein folding and translocation in the cell

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12 December 2020

pH-induced denaturation of proteins: a single salt bridge contributes 3-5 kcal/mol to the free energy of folding of T4 lysozyme

1 reference

12 December 2020

Synthesis, purification and initial structural characterization of octarellin, a de novo polypeptide modelled on the alpha/beta-barrel proteins.

1 reference

12 December 2020

Some factors in the interpretation of protein denaturation

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12 December 2020

An early intermediate in the folding of ribonuclease A is protected against cleavage by pepsin

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12 December 2020

Evolution and the tertiary structure of proteins

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12 December 2020

Ribonuclease A: carbon-13 nuclear magnetic resonance assignments, binding sites, and conformational flexibility

1 reference

12 December 2020

Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function

1 reference

12 December 2020

Principles that determine the structure of proteins

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12 December 2020

Folding of ribonuclease A from a partially disordered conformation. Kinetic study under transition conditions

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12 December 2020

Hydrogen bonding in globular proteins

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12 December 2020

Kinetic role of a meta-stable native-like two-disulphide species in the folding transition of bovine pancreatic trypsin inhibitor

1 reference

12 December 2020

Characterization of the transition state of lysozyme unfolding. I. Effect of protein-solvent interactions on the transition state

1 reference

12 December 2020

Characterization of the transition state of lysozyme unfolding. II. Effects of the intrachain crosslinking and the inhibitor binding on the transition state

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12 December 2020

Identifiers

DOI

10.1042/BJ2700001

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25 September 2019

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25 September 2019

PubMed publication ID

2204340

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