Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis (Q58235025)

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9 November 2019

title

Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis (English)

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9 November 2019

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9 November 2019

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9 November 2019

Flavell RA

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9 November 2019

Medema JP

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9 November 2019

Scaffidi C

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9 November 2019

Zheng TS

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9 November 2019

Melief CJ

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9 November 2019

Offringa R

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9 November 2019

Krammer PH

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9 November 2019

language of work or name

English

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publication date

1 December 1997

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European Journal of Immunology

9 November 2019

published in

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9 November 2019

volume

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9 November 2019

issue

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9 November 2019

page(s)

3492-3498

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Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity

9 November 2019

cites work

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https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

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https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

The CTL's kiss of death

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https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Purified perforin induces target cell lysis but not DNA fragmentation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

A natural killer cell granule protein that induces DNA fragmentation and apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

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https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

ICE family proteases: mediators of all apoptotic cell death?

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Activation of an interleukin 1 converting enzyme-dependent apoptosis pathway by granzyme B.

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https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Cleavage of CPP32 by granzyme B represents a critical role for granzyme B in the induction of target cell DNA fragmentation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Decreased tumor surveillance in perforin-deficient mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Granzyme A-deficient mice retain potent cell-mediated cytotoxicity.

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https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Differential inhibition of the Fas- and granule-mediated cytolysis pathways by the orthopoxvirus cytokine response modifier A/SPI-2 and SPI-1 protein

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271250

7 January 2021

Identifiers

DOI

10.1002/EJI.1830271250

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9464839%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

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