Caspase 3 (Q5049057)

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mammalian protein found in Homo sapiens
  • SCA-1
  • CASP-3
  • caspase-3
  • caspase 3, apoptosis-related cysteine protease
  • SREBP cleavage activity 1
  • protein Yama
  • caspase 3, apoptosis-related cysteine peptidase
  • CASP3
  • PARP cleavage protease
  • cysteine protease CPP32
  • apopain
  • CPP-32
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Language Label Description Also known as
English
Caspase 3
mammalian protein found in Homo sapiens
  • SCA-1
  • CASP-3
  • caspase-3
  • caspase 3, apoptosis-related cysteine protease
  • SREBP cleavage activity 1
  • protein Yama
  • caspase 3, apoptosis-related cysteine peptidase
  • CASP3
  • PARP cleavage protease
  • cysteine protease CPP32
  • apopain
  • CPP-32

Statements

molecular function
protein binding
determination method or standard
IPI
15 references
retrieved
9 May 2019
stated in
Casper is a FADD- and caspase-related inducer of apoptosis
GOA
curator
UniProt
UniProt protein ID
P42574
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
Tau cleavage and dephosphorylation in cerebellar granule neurons undergoing apoptosis
GOA
curator
UniProt
UniProt protein ID
P42574
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1
GOA
curator
UniProt
UniProt protein ID
P42574
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
Structural basis for the inhibition of caspase-3 by XIAP
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
Caspase-3-mediated cleavage of Akt: involvement of non-consensus sites and influence of phosphorylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
Protein kinase WNK3 increases cell survival in a caspase-3-dependent pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
Executioner caspase-3 and caspase-7 are functionally distinct proteases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
retrieved
9 May 2019
stated in
Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IPI
cysteine-type endopeptidase activity
determination method or standard
IDA
TAS
IEA
6 references
retrieved
9 May 2019
stated in
HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
TAS
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IEA
retrieved
9 May 2019
stated in
Huntingtin promotes cell survival by preventing Pak2 cleavage
GOA
curator
UniProt
UniProt protein ID
P42574
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IDA
retrieved
9 May 2019
stated in
Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop
GOA
curator
UniProt
UniProt protein ID
P42574
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IDA
retrieved
9 May 2019
stated in
Protective role of Cop in Rip2/caspase-1/caspase-4-mediated HeLa cell death
GOA
curator
UniProt
UniProt protein ID
P42574
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42574
determination method or standard
IDA
cell component
biological process

Identifiers

PDB structure ID
 
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