A novel germline mutation in Big Blue mice (Q50455408)

14 March 2018

title

A novel germline mutation in Big Blue mice (English)

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14 March 2018

author name string

Rory A Crabbe

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14 March 2018

Anita Prtenjaca

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14 March 2018

Heather E Tarnowski

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14 March 2018

Kathleen A Hill

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14 March 2018

publication date

1 March 2009

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14 March 2018

Environmental and Molecular Mutagenesis

published in

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14 March 2018

volume

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14 March 2018

issue

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page(s)

114-120

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14 March 2018

Large deletion detected with the Big Blue transgenic mouse mutagenesis assay

cites work

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Spontaneous mutation frequencies and spectra in p53 (+/+) and p53 (-/-) mice: a test of the 'guardian of the genome' hypothesis in the Big Blue transgenic mouse mutation detection system

21 January 2018

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Evidence that proximal multiple mutations in Big Blue transgenic mice are dependent events

21 January 2018

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High plating density improves Big Blue system efficiency without loss of sensitivity

21 January 2018

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The Big Blue(R) transgenic mouse mutation detection assay: the mutation pattern of sectored mutant plaques

21 January 2018

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Spontaneous multiple mutations show both proximal spacing consistent with chronocoordinate events and alterations with p53-deficiency

21 January 2018

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Protective effect of green tea against benzo[a]pyrene-induced mutations in the liver of Big Blue transgenic mice

21 January 2018

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Mutation frequency is reduced in the cerebellum of Big Blue mice overexpressing a human wild type SOD1 gene

21 January 2018

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Towards validation of the Big Blue transgenic mouse mutagenesis assay: the mutational spectrum of ex vivo pinpoint mutant plaques

21 January 2018

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Age-associated increase of spontaneous mutant frequency and molecular nature of mutation in newborn and old lacZ-transgenic mouse.

21 January 2018

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Intralaboratory optimization and standardization of mutant screening conditions used for a lambda/lacI transgenic mouse mutagenesis assay (I).

21 January 2018

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Mutant frequencies and mutation spectra of dimethylnitrosamine (DMN) at the lacI and cII loci in the livers of Big Blue transgenic mice

21 January 2018

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Interpretation of mutational spectra from different genes: analyses of PhIP-induced mutational specificity in the lacI and cII transgenes from colon of Big Blue rats

21 January 2018

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Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions and frameshifts

21 January 2018

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7 January 2021

Transmission of mutations in the lacI transgene to the offspring of ENU-treated Big Blue male mice

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7 January 2021

Tandem-base mutations occur in mouse liver and adipose tissue preferentially as G:C to T:A transversions and accumulate with age.

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7 January 2021

Sequence of the lacI gene

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7 January 2021

Spontaneous mutations in the Big Blue transgenic system are primarily mouse derived

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7 January 2021

Spontaneous mutation in Big Blue mice from fetus to old age: tissue-specific time courses of mutation frequency but similar mutation types

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7 January 2021

Tissue-specific time courses of spontaneous mutation frequency and deviations in mutation pattern are observed in middle to late adulthood in Big Blue mice.

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7 January 2021

Most spontaneous tumors in a mouse model of Li-Fraumeni syndrome do not have a mutator phenotype.

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7 January 2021

The use of transgenic mice for short-term, in vivo mutagenicity testing

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7 January 2021

Analysis of spontaneous and induced mutations in transgenic mice using a lambda ZAP/lacl shuttle vector

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7 January 2021

Detailed review of transgenic rodent mutation assays

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7 January 2021

ENU administration causes genomic instability along with single nucleotide polymorphisms in p53 during gliomagenesis: T11TS administration demonstrated in vivo apoptosis of these genetically altered tumor cells

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7 January 2021

LacI mutation spectra following benzo[a]pyrene treatment of Big Blue mice

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7 January 2021

The genetic analysis of lacI mutations in sectored plaques from Big Blue transgenic mice

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7 January 2021

Evidence for mutation showers

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7 January 2021

Identifiers

DOI

10.1002/EM.20442

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14 March 2018

release_gxrwbbvgerdatmsvl6igvs2q24

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/gxrwbbvgerdatmsvl6igvs2q24

24 November 2022

mapped directly with Wikidata item

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14 March 2018