Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm (Q46785400)

25 December 2017

title

Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm (English)

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25 December 2017

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Shinya Yamanaka

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25 December 2017

Kazutoshi Takahashi

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25 December 2017

Kenta Sutou

Kenta Sutou

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25 December 2017

Mari Ohnuki

Mari Ohnuki

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25 December 2017

Megumi Narita

Megumi Narita

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25 December 2017

Koji Tanabe

Koji Tanabe

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25 December 2017

author name string

Aki Sasaki

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25 December 2017

Masamichi Yamamoto

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25 December 2017

Michiko Nakamura

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25 December 2017

Kenji Osafune

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25 December 2017

language of work or name

English

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publication date

24 April 2014

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25 December 2017

published in

Nature Communications

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25 December 2017

volume

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25 December 2017

page(s)

3678

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25 December 2017

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

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A molecular roadmap of reprogramming somatic cells into iPS cells

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High-resolution analysis with novel cell-surface markers identifies routes to iPS cells

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Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase

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Three monoclonal antibodies defining distinct differentiation antigens associated with different high molecular weight polypeptides on the surface of human embryonal carcinoma cells

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Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells

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Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts

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FGF2 sustains NANOG and switches the outcome of BMP4-induced human embryonic stem cell differentiation

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Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak-like cells and enables isolation of primitive hematopoietic precursors.

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The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming

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Direct cell reprogramming is a stochastic process amenable to acceleration

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Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

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A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

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Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

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Linking the p53 tumour suppressor pathway to somatic cell reprogramming

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Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming

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A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts

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The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse

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FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse

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Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1.

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Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

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Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells

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Plat-E: an efficient and stable system for transient packaging of retroviruses

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Efficient establishment of human embryonic stem cell lines and long-term maintenance with stable karyotype by enzymatic bulk passage

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The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

21 January 2018

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A more efficient method to generate integration-free human iPS cells

21 January 2018

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Promotion of direct reprogramming by transformation-deficient Myc.

21 January 2018

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Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells

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Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells

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Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

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Small-molecule inhibitors of bone morphogenic protein and activin/nodal signals promote highly efficient neural induction from human pluripotent stem cells.

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Telomerase maintains telomere structure in normal human cells.

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A ROCK inhibitor permits survival of dissociated human embryonic stem cells

21 January 2018

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Elite and stochastic models for induced pluripotent stem cell generation

21 January 2018

1 reference

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The Ink4/Arf locus is a barrier for iPS cell reprogramming

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Small but effective moves towards a greener China

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1038/NCOMMS4678

Identifiers

DOI

10.1038/NCOMMS4678

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25 December 2017

ADS bibcode

2014NatCo...5.3678T

0 references

1 reference

25 December 2017