Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition. (Q44697049)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20848438%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition (English)

1 reference

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head and neck squamous cell carcinoma

14 February 2020

main subject

0 references

1 reference

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14 February 2020

Uttam K Sinha

1 reference

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14 February 2020

Victor J Schorn

1 reference

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14 February 2020

Christian Hochstim

1 reference

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14 February 2020

Sutao Zhu

1 reference

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14 February 2020

Rizwan Masood

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14 February 2020

publication date

1 February 2011

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14 February 2020

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14 February 2020

volume

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14 February 2020

issue

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14 February 2020

page(s)

178-188

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Global cancer statistics, 2002

14 February 2020

cites work

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Sphingosine 1-phosphate preserves fertility in irradiated female mice without propagating genomic damage in offspring

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EphB4 provides survival advantage to squamous cell carcinoma of the head and neck

21 January 2018

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Emerging perspectives in epidermal growth factor receptor targeting in head and neck cancer

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Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C(18)-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis

21 January 2018

1 reference

Enhancement of radiosensitivity by combined ceramide and dimethylsphingosine treatment in lung cancer cells

21 January 2018

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Overexpression of sphingosine-1-phosphate lyase or inhibition of sphingosine kinase in Dictyostelium discoideum results in a selective increase in sensitivity to platinum-based chemotherapy drugs

21 January 2018

1 reference

Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1.

21 January 2018

1 reference

Chemosensitizing effects of sphingosine kinase-1 inhibition in prostate cancer cell and animal models.

21 January 2018

1 reference

Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis.

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Downregulating sphingosine kinase-1 for cancer therapy

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Sphingosine kinase 1 expression is regulated by signaling through PI3K, AKT2, and mTOR in human coronary artery smooth muscle cells

1 reference