Preferential closed channel blockade of HERG potassium currents by chemically synthesised BeKm-1 scorpion toxin (Q44512868)

3 December 2017

title

Preferential closed channel blockade of HERG potassium currents by chemically synthesised BeKm-1 scorpion toxin (English)

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3 December 2017

James T Milnes

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3 December 2017

Christopher E Dempsey

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3 December 2017

John M Ridley

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3 December 2017

Olivia Crociani

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3 December 2017

Annarosa Arcangeli

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3 December 2017

Jules C Hancox

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3 December 2017

Harry J Witchel

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3 December 2017

language of work or name

English

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publication date

1 July 2003

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3 December 2017

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3 December 2017

volume

547

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3 December 2017

issue

1-3

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3 December 2017

page(s)

20-26

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3 December 2017

cites work

I(Kr): the hERG channel

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Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels

21 January 2018

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Blocking effects of the antiarrhythmic drug propafenone on the HERG potassium channel

21 January 2018

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A structural basis for drug-induced long QT syndrome

21 January 2018

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X-ray structure of a voltage-dependent K+ channel

21 January 2018

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The open pore conformation of potassium channels

21 January 2018

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The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

21 January 2018

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Mapping the receptor site for ergtoxin, a specific blocker of ERG channels

21 January 2018

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Mapping the binding site of a human ether-a-go-go-related gene-specific peptide toxin (ErgTx) to the channel's outer vestibule

21 January 2018

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M-type K+ current inhibition by a toxin fron the scorpion Buthus eupeus.

21 January 2018

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An ERG channel inhibitor from the scorpion Buthus eupeus

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BeKm-1 Is a HERG-Specific Toxin that Shares the Structure with ChTx but the Mechanism of Action with ErgTx1

21 January 2018

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Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature

21 January 2018

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The calcium-independent transient outward potassium current in isolated ferret right ventricular myocytes. II. Closed state reverse use-dependent block by 4-aminopyridine

21 January 2018

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Blockade of HERG potassium currents by fluvoxamine: incomplete attenuation by S6 mutations at F656 or Y652

21 January 2018

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Spironolactone and its main metabolite, canrenoic acid, block human ether-a-go-go-related gene channels

21 January 2018

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Intrinsic helical propensities and stable secondary structure in a membrane-bound fragment (S4) of the shaker potassium channel

21 January 2018

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New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1

21 January 2018

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Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels

21 January 2018

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Cellular mechanism of aminoglycoside tolerance in long-term gentamicin treatment

21 January 2018

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Self-association of disulfide-dimerized melittin analogues

7 January 2021

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The asparagine-stabilized beta-turn of apamin: contribution to structural stability from dynamics simulation and amide hydrogen exchange analysis

7 January 2021

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A four-disulphide-bridged toxin, with high affinity towards voltage-gated K+ channels, isolated from Heterometrus spinnifer (Scorpionidae) venom

7 January 2021

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Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K+ channel. Open-channel block by methanesulfonanilides

7 January 2021

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Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide

7 January 2021

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10.1016/S0014-5793(03)00662-8

7 January 2021

Identifiers

DOI

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3 December 2017

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