Class II Transactivator (CIITA) Promoter Methylation Does Not Correlate with Silencing of CIITA Transcription in Trophoblasts1 (Q44441811)

3 December 2017

title

Class II transactivator (CIITA) promoter methylation does not correlate with silencing of CIITA transcription in trophoblasts (English)

1 reference

3 December 2017

Class II Transactivator (CIITA) Promoter Methylation Does Not Correlate with Silencing of CIITA Transcription in Trophoblasts1 (English)

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

2 January 2024

1 reference

https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

2 January 2024

Renae Holtz

1 reference

3 December 2017

Jason C. Choi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12748124

2 January 2024

Margaret G. Petroff

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12748124

2 January 2024

Janet F. Piskurich

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12748124

2 January 2024

Shawn P. Murphy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12748124

2 January 2024

language of work or name

English

1 reference

inferred from

Biology of Reproduction

publication date

14 May 2003

1 reference

full work available at URL

3 December 2017

https://academic.oup.com/biolreprod/article-pdf/69/3/915/10587795/biolreprod0915.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12748124

http://academic.oup.com/biolreprod/article-pdf/69/3/915/10587795/biolreprod0915.pdf

2 January 2024

file format

Portable Document Format

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

2 January 2024

published in

Biology of Reproduction

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3 December 2017

1 reference

3 December 2017

1 reference

3 December 2017

page(s)

915-924

1 reference

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

3 December 2017

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Death-inducing tumour necrosis factor (TNF) superfamily ligands and receptors are transcribed in human placentae, cytotrophoblasts, placental macrophages and placental cell lines

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Class II transactivator: mastering the art of major histocompatibility complex expression

2 January 2024

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Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA.

2 January 2024

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Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.

2 January 2024

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Molecular analysis of G1B and G3A IFN gamma mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction

2 January 2024

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MHC class II gene silencing in trophoblast cells is caused by inhibition of CIITA expression

2 January 2024

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Lack of CIITA expression is central to the absence of antigen presentation functions of trophoblast cells and is caused by methylation of the IFN-gamma inducible promoter (PIV) of CIITA.

2 January 2024

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Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA.

2 January 2024

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Activated human T cells accomplish MHC class II expression through T cell-specific occupation of class II transactivator promoter III

2 January 2024

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Activation of the MHC class II transactivator CIITA by interferon-gamma requires cooperative interaction between Stat1 and USF-1

2 January 2024

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Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta

2 January 2024

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Isolation of a B-cell-specific promoter for the human class II transactivator

2 January 2024

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

2 January 2024

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Kinetics of a gamma interferon response: expression and assembly of CIITA promoter IV and inhibition by methylation

2 January 2024

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Interferon-gamma-induced chromatin remodeling at the CIITA locus is BRG1 dependent

2 January 2024

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Methylation of class II trans-activator promoter IV: a novel mechanism of MHC class II gene control

2 January 2024

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Transcriptional control of MHC genes in fetal trophoblast cells

2 January 2024

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Purification, Characterization, andin vitroDifferentiation of Cytotrophoblasts from Human Term Placentae*

2 January 2024

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Isolation of pure villous cytotrophoblast from term human placenta using immunomagnetic microspheres

2 January 2024

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DNA alkylating agents alleviate silencing of class II transactivator gene expression in L1210 lymphoma cells

2 January 2024

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Dominant negative suppression of major histocompatibility complex genes occurs in trophoblasts

2 January 2024

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A novel element and a TEF-2-like element activate the major histocompatibility complex class II transactivator in B-lymphocytes

2 January 2024

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Differential selectivity of CIITA promoter activation by IFN-gamma and IRF-1 in astrocytes and macrophages: CIITA promoter activation is not affected by TNF-alpha

2 January 2024

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Malignant glioma cells use MHC class II transactivator (CIITA) promoters III and IV to direct IFN-gamma-inducible CIITA expression and can function as nonprofessional antigen presenting cells in endocytic processing and CD4(+) T-cell activation.

2 January 2024

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Deficient induction of human hsp70 heat shock gene transcription in Y79 retinoblastoma cells despite activation of heat shock factor 1.

2 January 2024

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Methylation-associated Transcriptional Silencing of the Major Histocompatibility Complex-linked hsp70 Genes in Mouse Cell Lines

2 January 2024

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High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines.

2 January 2024

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https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

De novo methylation of the MyoD1 CpG island during the establishment of immortal cell lines

2 January 2024

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Chromatin remodeling and the control of gene expression

2 January 2024

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ATP-dependent remodeling and acetylation as regulators of chromatin fluidity

2 January 2024

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Activation of MHC class I, II, and CD40 gene expression by histone deacetylase inhibitors

2 January 2024

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Involvement of CREB binding protein in expression of major histocompatibility complex class II genes via interaction with the class II transactivator

2 January 2024

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Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes

2 January 2024

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Transcriptional coactivator, CIITA, is an acetyltransferase that bypasses a promoter requirement for TAF(II)250

2 January 2024

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Active suppression of major histocompatibility complex class II gene expression during differentiation from B cells to plasma cells.

2 January 2024

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Negative trans-acting factors extinguish Ia expression in B cell-L 929 somatic cell hybrids

2 January 2024

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Active suppression of the class II transactivator-encoding AIR-1 locus is responsible for the lack of major histocompatibility complex class II gene expression observed during differentiation from B cells to plasma cells

2 January 2024

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https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

CIITA B-cell-specific promoter suppression in MHC class II-silenced cell hybrids

2 January 2024

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Human choriocarcinoma-derived JEG-3 cells transfected with murine MHC class II Aq expression vectors present antigen to Aq-restricted murine T-cell hybridoma

2 January 2024

1 reference

https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

In vivo class II transactivator expression in mice is induced by a non-interferon-gamma mechanism in response to local injury

2 January 2024

1 reference

https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

CpG methylation, chromatin structure and gene silencing-a three-way connection

2 January 2024

1 reference

https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

DNA methylation and chromatin modification.

2 January 2024

1 reference

https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

DNA methylation prevents transfection of genes for specific surface antigens

2 January 2024

1 reference

https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

Transfected trophoblast-derived human cells can express a single HLA class I allelic product

2 January 2024

1 reference

https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

HLA-E is the only class I gene that escapes CpG methylation and is transcriptionally active in the trophoblast-derived human cell line JAR.

2 January 2024

1 reference

https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

Lack of IFN-gamma-mediated induction of the class II transactivator (CIITA) through promoter methylation is predominantly found in developmental tumor cell lines

2 January 2024

1 reference

https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

BLIMP-I mediates extinction of major histocompatibility class II transactivator expression in plasma cells

2 January 2024

1 reference

https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

Positive regulatory domain I binding factor 1 silences class II transactivator expression in multiple myeloma cells

2 January 2024

1 reference

https://api.crossref.org/works/10.1095/BIOLREPROD.103.017103

Regulation of IL-4 expression by activation of individual alleles

2 January 2024

1 reference

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2 January 2024

Identifiers

DOI

1 reference

3 December 2017

1 reference