Astrocytes accumulate Aβ42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains (Q44410484)

2 December 2017

title

Astrocytes accumulate A beta 42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains (English)

1 reference

2 December 2017

Astrocytes accumulate Aβ42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains (English)

1 reference

https://api.crossref.org/works/10.1016/S0006-8993(03)02361-8

26 December 2023

0 references

0 references

Hoau-Yan Wang

1 reference

2 December 2017

author name string

Venkateswar Venkataraman

1 reference

2 December 2017

Robert G. Nagele

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12706236

26 December 2023

Michael R. D'Andrea

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12706236

26 December 2023

H. Lee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12706236

26 December 2023

language of work or name

English

0 references

publication date

1 May 2003

1 reference

2 December 2017

9 May 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12706236

full work available at URL

26 December 2023

number of pages

1 reference

based on heuristic

inferred from page(s)

https://api.elsevier.com/content/article/PII:S0006899303023618?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0006-8993(03)02361-8

https://api.elsevier.com/content/article/PII:S0006899303023618?httpAccept=text/plain

26 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0006-8993(03)02361-8

26 December 2023

1 reference

2 December 2017

volume

971

1 reference

2 December 2017

1 reference

2 December 2017

page(s)

197-209

1 reference

Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of beta-amyloid protein

2 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Occurrence of the diffuse amyloid beta-protein (Abeta) deposits with numerous Abeta-containing glial cells in the cerebral cortex of patients with Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Dynamic signaling between astrocytes and neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Cellular expression of alpha7 nicotinic acetylcholine receptor protein in the temporal cortex in Alzheimer's and Parkinson's disease--a stereological approach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Astrocytes and microglial cells incorporate degenerating fibers following entorhinal lesion: a light, confocal, and electron microscopical study using a phagocytosis-dependent labeling technique

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Quantitative assessment of nicotinic acetylcholine receptor proteins in the cerebral cortex of Alzheimer patients.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Response of striatal astrocytes to neuronal deafferentation: an immunocytochemical and ultrastructural study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Cholinergic markers in elderly patients with early signs of Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

7 January 2021

GFAP and astrogliosis

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Glial cell extracellular matrix: boundaries for axon growth in development and regeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Intraneuronal Abeta42 accumulation in human brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

beta-Amyloid immunoreactivity in astrocytes in Alzheimer's disease brain biopsies: an electron microscope study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Amyloid plaque core protein in Alzheimer disease and Down syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

The role of activated astrocytes and of the neurotrophic cytokine S100B in the pathogenesis of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Human nicotinic receptors--their role in aging and dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Rapid appearance of beta-amyloid precursor protein immunoreactivity in damaged axons and reactive glial cells in rat brain following needle stab injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Correlation of nicotinic binding with neurochemical markers in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Synaptic density in the inner molecular layer of the hippocampal dentate gyrus in Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Quantitative assessment of possible age-related change in synaptic numbers in the human frontal cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

The molecular pathology of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Normal and abnormal biology of the beta-amyloid precursor protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Amyloid beta protein (A beta) removal by neuroglial cells in culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

The role of the amyloid protein precursor (APP) in Alzheimer's disease: does the normal function of APP explain the topography of neurodegeneration?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Amyloid beta-protein (Abeta)-containing astrocytes are located preferentially near N-terminal-truncated Abeta deposits in the human entorhinal cortex.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Control of synapse number by glia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Glia-neuron intercommunications and synaptic plasticity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Cerebellar diffuse amyloid plaques are derived from dendritic Abeta42 accumulations in Purkinje cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Nicotinic receptors and neurodegenerative dementing diseases: basic research and clinical implications.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Glial fibrillary acidic protein is necessary for mature astrocytes to react to beta-amyloid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Diffuse plaques associated with astroglial amyloid beta protein, possibly showing a disappearing stage of senile plaques.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Evidence that Aβ42 is the real culprit in alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Beta-secretase processing of the beta-amyloid precursor protein in transgenic mice is efficient in neurons but inefficient in astrocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2803%2902361-8

Astrocytic response to injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-8993(03)02361-8

Assessment of amyloid beta-protein precursor gene mutations in a large set of familial and sporadic Alzheimer disease cases

26 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0006-8993(03)02361-8

26 December 2023

Identifiers

1 reference

2 December 2017

1 reference