A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism (Q44163171)

30 November 2017

title

A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism (English)

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30 November 2017

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Ted M Dawson

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30 November 2017

Allen S Mandir

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30 November 2017

Cynthia M Simbulan-Rosenthal

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30 November 2017

Marc F Poitras

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30 November 2017

John R Lumpkin

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30 November 2017

Valina L Dawson

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30 November 2017

Mark E Smulson

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30 November 2017

language of work or name

English

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publication date

1 October 2002

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Journal of Neurochemistry

30 November 2017

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inferred from page(s)

published in

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30 November 2017

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30 November 2017

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30 November 2017

page(s)

186-192

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Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.

30 November 2017

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Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

21 January 2018

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Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease

21 January 2018

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Loss of function and p53 protein stabilization

21 January 2018

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Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

21 January 2018

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Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

21 January 2018

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Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase

21 January 2018

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Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase

21 January 2018

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Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons

21 January 2018

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Increase in bax expression in substantia nigra following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment of mice

21 January 2018

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Bright and dark sides of nitric oxide in ischemic brain injury

21 January 2018

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Manganese superoxide dismutase overexpression attenuates MPTP toxicity.

21 January 2018

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Role of reactive oxygen species in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity

21 January 2018

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Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

21 January 2018

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Regulation and activation of p53 and its family members

21 January 2018

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Nitric oxide synthase inhibition and MPTP-induced toxicity in the common marmoset

21 January 2018

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Poly(ADP-ribose) binds to specific domains of p53 and alters its DNA binding functions

21 January 2018

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UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

21 January 2018

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Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism

21 January 2018

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Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes

21 January 2018

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Mechanisms of switching on p53: a role for covalent modification?

21 January 2018

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MDM2--master regulator of the p53 tumor suppressor protein

21 January 2018

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Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity

21 January 2018

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Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

21 January 2018

1 reference

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Neuronal nitric oxide synthase inhibition reduces MPP+-evoked hydroxyl radical formation but not dopamine efflux in rat striatum

21 January 2018

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7-Nitroindazole prevents 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-induced ATP loss in the mouse striatum

21 January 2018

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Neurochemical findings in the MPTP model of Parkinson's disease

21 January 2018

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Poly(ADP-ribosyl)ation of p53 in vitro and in vivo modulates binding to its DNA consensus sequence

21 January 2018

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Roles of poly(ADP-ribosyl)ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1.

21 January 2018

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In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining

21 January 2018

1 reference

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Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity

21 January 2018

1 reference

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Caspase-3 activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice

21 January 2018

1 reference

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Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

21 January 2018

1 reference

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Poly(ADP-ribose) glycohydrolase is present and active in mammalian cells as a 110-kDa protein

21 January 2018

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Cell death and apoptosis regulating proteins in Parkinson's disease--a cautionary note

21 January 2018

1 reference

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Inhibition of neuronal nitric oxide synthase protects against MPTP toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.01144.X

10.1046/J.1471-4159.2002.01144.X

21 January 2018

Identifiers

DOI

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30 November 2017

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