Microglia express functional 11 beta-hydroxysteroid dehydrogenase type 1. (Q43026192)

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5 February 2020

title

Microglia express functional 11 beta-hydroxysteroid dehydrogenase type 1 (English)

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5 February 2020

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5 February 2020

Bruce S McEwen

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5 February 2020

author name string

Andres Gottfried-Blackmore

series ordinal

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5 February 2020

Renshan Ge

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5 February 2020

Karen Bulloch

series ordinal

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5 February 2020

publication date

1 August 2010

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5 February 2020

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5 February 2020

volume

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issue

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5 February 2020

page(s)

1257-1266

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11 Beta-hydroxysteroid dehydrogenase type 1 is induced in human monocytes upon differentiation to macrophages

5 February 2020

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Protection from direct cerebral cryptococcus infection by interferon-gamma-dependent activation of microglial cells

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Minireview: cellular redox state regulates hydroxysteroid dehydrogenase activity and intracellular hormone potency

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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

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Hippocampal 11beta-hydroxysteroid dehydrogenase type 1 messenger ribonucleic acid expression has a diurnal variability that is lost in the obese Zucker rat.

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7 January 2021

The down side of glucocorticoid receptor regulation.

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11Beta-hydroxysteroid dehydrogenase type 1--a role in inflammation?

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Enhancing versus suppressive effects of stress hormones on skin immune function

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Distinct ontogeny of glucocorticoid and mineralocorticoid receptor and 11beta-hydroxysteroid dehydrogenase types I and II mRNAs in the fetal rat brain suggest a complex control of glucocorticoid actions.

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Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease

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Identification of a kinetically distinct activity of 11beta-hydroxysteroid dehydrogenase in rat Leydig cells

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Local Amplification of Glucocorticoids by 11 -Hydroxysteroid Dehydrogenase Type 1 Promotes Macrophage Phagocytosis of Apoptotic Leukocytes

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Hexose-6-phosphate dehydrogenase and 11beta-hydroxysteroid dehydrogenase-1 tissue distribution in the rat

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Brain microglia express steroid-converting enzymes in the mouse

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Differential expression, function and response to inflammatory stimuli of 11beta-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation

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7 January 2021

Minireview: hexose-6-phosphate dehydrogenase and redox control of 11{beta}-hydroxysteroid dehydrogenase type 1 activity

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7 January 2021

11 Beta-hydroxysteroid dehydrogenases in the brain: two enzymes two roles

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7 January 2021

Attenuation of Hippocampal 11beta-Hydroxysteroid Dehydrogenase Type 1 by Chronic Psychosocial Stress in the Tree Shrew

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7 January 2021

11Beta hydroxysteroid dehydrogenase type 1 is expressed and is biologically active in human skeletal muscle

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7 January 2021

Endogenous selective inhibitors of 11beta-hydroxysteroid dehydrogenase isoforms 1 and 2 of adrenal origin

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Hexose-6-phosphate dehydrogenase knock-out mice lack 11 beta-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation

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7 January 2021

Leptin activation of corticosterone production in hepatocytes may contribute to the reversal of obesity and hyperglycemia in leptin-deficient ob/ob mice

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The brain is an important target of adrenal steroid actions. A comparison of synthetic and natural steroids

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11 beta-hydroxysteroid dehydrogenase bioactivity and messenger RNA expression in rat forebrain: localization in hypothalamus, hippocampus, and cortex

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7 January 2021

Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*

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7 January 2021

Glucocorticoids play a fundamental role in protecting the brain during innate immune response.

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7 January 2021

Microglia provide neuroprotection after ischemia

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7 January 2021

System Xc- and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-beta peptide 1-40.

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7 January 2021

Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function

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7 January 2021

11 beta-Hydroxysteroid dehydrogenase in cultured hippocampal cells reactivates inert 11-dehydrocorticosterone, potentiating neurotoxicity

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7 January 2021

11 Beta-hydroxysteroid dehydrogenase type 2 in the postnatal and adult rat brain

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7 January 2021

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7 January 2021

Stress, Glucocorticoids, and Damage to the Nervous System: The Current State of Confusion

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7 January 2021

A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse.

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7 January 2021

11beta-Hydroxysteroid dehydrogenase in the brain: a novel regulator of glucocorticoid action?

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7 January 2021

Steroid hormone receptor expression and function in microglia

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7 January 2021

Microglia derived from aging mice exhibit an altered inflammatory profile.

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7 January 2021

An inflammatory review of glucocorticoid actions in the CNS.

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7 January 2021

Microglia as neuroprotective, immunocompetent cells of the CNS.

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7 January 2021

Cortisol metabolism and the role of 11beta-hydroxysteroid dehydrogenase

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7 January 2021

Glucocorticoid regulation of the inflammatory response to injury

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7 January 2021

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

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7 January 2021

Identifiers

DOI

10.1002/GLIA.21007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20544861%20AND%20SRC:MED&resulttype=core&format=json

release_ocngayhycfdxnalvcjldkjov5e

5 February 2020

Fatcat ID

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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