Complement C5 (Q426181)

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mammalian protein found in Homo sapiens

C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
C5a anaphylatoxin
C5
anaphylatoxin C5a analog
prepro-C5
complement C5
complement component 5

Language	Label	Description	Also known as
English	Complement C5	mammalian protein found in Homo sapiens	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 C5a anaphylatoxin C5 anaphylatoxin C5a analog prepro-C5 complement C5 complement component 5

Statements

1 reference

13 November 2019

UniProt protein ID

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

Tissue inhibitor of metalloproteinases-like, OB-fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

Anaphylatoxin, complement system

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

Alpha-macroglobulin, receptor-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

Alpha-2-macroglobulin, protein family

1 reference

based on heuristic

inferred from protein domain or family

Alpha-macroglobulin, receptor-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

based on heuristic

inferred from protein domain or family

Macroglobulin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Alpha-2-macroglobulin, bait region domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Anaphylatoxin, complement system domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Netrin module, non-TIMP type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Alpha-macroglobulin, TED domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Netrin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

chemokine activity

determination method or standard

1 reference

8 April 2019

Differential ability of exogenous chemotactic agents to disrupt transendothelial migration of flowing neutrophils

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

endopeptidase inhibitor activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

signaling receptor binding

determination method or standard

extracellular region

determination method or standard

extracellular exosome

determination method or standard

biological process

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

complement activation, alternative pathway

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

immune system process

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

response to stress

determination method or standard

1 reference

31 October 2017

Expression of receptors for C5a anaphylatoxin (CD88) on human bronchial epithelial cells: enhancement of C5a-mediated release of IL-8 upon exposure to cigarette smoke

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01031&geneProductId=UniProtKB:P01031

determination method or standard

in utero embryonic development

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

positive regulation of angiogenesis

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

determination method or standard

1 reference

8 April 2019

Differential ability of exogenous chemotactic agents to disrupt transendothelial migration of flowing neutrophils

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

cell surface receptor signaling pathway

determination method or standard

1 reference

8 April 2019

Differential ability of exogenous chemotactic agents to disrupt transendothelial migration of flowing neutrophils

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

complement activation, classical pathway

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

positive regulation of vascular endothelial growth factor production

determination method or standard

inflammatory response

determination method or standard

3 references

8 April 2019

C3a and C5a are chemotaxins for human mast cells and act through distinct receptors via a pertussis toxin-sensitive signal transduction pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

regulation of complement activation

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

negative regulation of macrophage chemotaxis

determination method or standard

1 reference

8 April 2019

An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

negative regulation of endopeptidase activity

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

innate immune response

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

cell chemotaxis

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

complement activation

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01031

determination method or standard

Gene Atlas image

PBB GE C5 205500 at fs.png
732 × 530; 10 KB

0 references

subject has role

immunologic factor

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

http://purl.uniprot.org/uniprot/P01031

1 reference

Identifiers.org

Netrin module, non-TIMP type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

Alpha-2-macroglobulin, bait region domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

Alpha-2-macroglobulin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

Macroglobulin domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

Anaphylatoxin, complement system domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

Anaphylatoxin/fibulin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

Alpha-macroglobulin, TED domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

Alpha-macroglobulin, receptor-binding

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01031

complement component 5a

0 references

0 references

Identifiers

MeSH descriptor ID

subject named as

Complement C5

0 references

D12.776.124.486.274.450

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000223642

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000223642

0 references

Microsoft Academic ID

0 references

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(6 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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