Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease (Q42377919)

28 October 2017

Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease (English)

1 reference

non-alcoholic fatty liver

28 October 2017

1 reference

1 reference

metabolic dysfunction–associated steatotic liver disease

1 reference

Hans-Ulrich Häring

1 reference

28 October 2017

Norbert Stefan

1 reference

28 October 2017

Thomas Laeger

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Andreas Fritsche

1 reference

28 October 2017

Sophie Saussenthaler

1 reference

28 October 2017

Christian Baumeier

1 reference

28 October 2017

Luisa Schlüter

1 reference

28 October 2017

Maria Rödiger

1 reference

28 October 2017

Stella Amelie Alaze

1 reference

28 October 2017

Louise Fritsche

1 reference

28 October 2017

Robert Wolfgang Schwenk

1 reference

28 October 2017

Annette Schürmann

1 reference

28 October 2017

4 August 2017

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28 October 2017

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28 October 2017

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28 October 2017

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28 October 2017

1254-1263

1 reference

describes a project that uses

28 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641684/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Dipeptidyl peptidase-4 impairs insulin signaling and promotes lipid accumulation in hepatocytes

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Middle east respiratory syndrome corona virus spike glycoprotein suppresses macrophage responses via DPP4-mediated induction of IRAK-M and PPARγ.

28 May 2018

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Identification of Potential Plasma Biomarkers for Nonalcoholic Fatty Liver Disease by Integrating Transcriptomics and Proteomics in Laying Hens

28 May 2018

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Hepatic DPP4 DNA Methylation Associates With Fatty Liver.

28 May 2018

1 reference

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The pro-fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride-induced experimental liver injury.

28 May 2018

1 reference

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Linagliptin alleviates fatty liver disease in diabetic db/db mice

28 May 2018

1 reference

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Reduced DPP4 activity improves insulin signaling in primary human adipocytes.

28 May 2018

1 reference

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Nonalcoholic fatty liver disease: a systematic review

28 May 2018

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Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice

28 May 2018

1 reference

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Dipeptidyl peptidase-4 inhibition ameliorates Western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function

28 May 2018

1 reference

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Challenges and opportunities in drug and biomarker development for nonalcoholic steatohepatitis: findings and recommendations from an American Association for the Study of Liver Diseases-U.S. Food and Drug Administration Joint Workshop

28 May 2018

1 reference

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GLP-1-oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand obese (NZO) mice

28 May 2018

1 reference

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Circulating dipeptidyl peptidase-4 activity correlates with measures of hepatocyte apoptosis and fibrosis in non-alcoholic fatty liver disease in type 2 diabetes mellitus and obesity: A dual cohort cross-sectional study

28 May 2018

1 reference

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Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs.

28 May 2018

1 reference

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Transcriptome analysis of PPARγ target genes reveals the involvement of lysyl oxidase in human placental cytotrophoblast invasion

28 May 2018

1 reference

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Adipose dipeptidyl peptidase-4 and obesity: correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro

28 May 2018

1 reference

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Diet-induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism

28 May 2018

1 reference

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Dipeptidyl peptidase-4: a key player in chronic liver disease

28 May 2018

1 reference

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The role of adipokines in β-cell failure of type 2 diabetes

28 May 2018

1 reference

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Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-γ expression.

28 May 2018

1 reference

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Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology

28 May 2018

1 reference

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Non-invasive quantification of white and brown adipose tissues and liver fat content by computed tomography in mice

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Histone deacetylase 6 (HDAC6) is an essential modifier of glucocorticoid-induced hepatic gluconeogenesis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Serum Dipeptidyl Peptidase-4 Activity in Insulin Resistant Patients with Non-Alcoholic Fatty Liver Disease: A Novel Liver Disease Biomarker

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Increased expression of PPARgamma in high fat diet-induced liver steatosis in mice.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV.

28 May 2018

1 reference

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Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistance

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Prevention and treatment effect of evogliptin on hepatic steatosis in high-fat-fed animal models.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Hepatocyte-specific, PPARγ-regulated mechanisms to promote steatosis in adult mice

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Soluble DPP-4 up-regulates toll-like receptors and augments inflammatory reactions, which are ameliorated by vildagliptin or mannose-6-phosphate.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Soluble DPP4 induces inflammation and proliferation of human smooth muscle cells via protease-activated receptor 2.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Diet-dependent alterations of hepatic Scd1 expression are accompanied by differences in promoter methylation

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Dipeptidyl peptidase 4-deficient rats have improved bile secretory function in high fat diet-induced steatosis

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Up-regulation of PPAR-gamma mRNA expression in the liver of obese patients: an additional reinforcing lipogenic mechanism to SREBP-1c induction

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Dipeptidyl peptidase IV (DDP IV) in NASH patients.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5641684

Altered zonal expression of the CD26 antigen (dipeptidyl peptidase IV) in human cirrhotic liver

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29031724

12 December 2020

inferred from PubMed ID database lookup

Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29031724

12 December 2020

inferred from PubMed ID database lookup

Increased hepatic expression of dipeptidyl peptidase-4 in non-alcoholic fatty liver disease and its association with insulin resistance and glucose metabolism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29031724

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.MOLMET.2017.07.016

1 reference

28 October 2017

1 reference

28 October 2017

PubMed publication ID

29031724

1 reference