Structure-function analysis of the alpha5 and the alpha13 helices of human glucokinase: description of two novel activating mutations. (Q41940930)

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13 January 2020

title

Structure-function analysis of the alpha5 and the alpha13 helices of human glucokinase: description of two novel activating mutations (English)

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13 January 2020

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Maria Adelaida Garcia-Gimeno

13 January 2020

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13 January 2020

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13 January 2020

Leda Pedelini

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13 January 2020

Juan M Gomez-Zumaquero

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13 January 2020

Pablo Rodriguez-Bada

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13 January 2020

Soledad López-Enriquez

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13 January 2020

Federico C Soriguer

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13 January 2020

Antonio L Cuesta-Muñoz

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13 January 2020

publication date

29 June 2005

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13 January 2020

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13 January 2020

volume

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13 January 2020

issue

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13 January 2020

page(s)

2080-2086

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Raster3D: photorealistic molecular graphics

13 January 2020

cites work

1 reference

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Electron-density map interpretation

5 June 2018

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Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase

5 June 2018

1 reference

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Glucokinase (GCK) mutations in hyper- and hypoglycemia: Maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy

5 June 2018

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Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations

5 June 2018

1 reference

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Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function

5 June 2018

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Regulation of pancreatic beta-cell glucokinase: from basics to therapeutics

5 June 2018

1 reference

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Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities.

5 June 2018

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Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm

5 June 2018

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Glucokinase as pancreatic beta cell glucose sensor and diabetes gene

5 June 2018

1 reference

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Variable effects of maturity-onset-diabetes-of-youth (MODY)-associated glucokinase mutations on substrate interactions and stability of the enzyme

5 June 2018

1 reference

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Expression of the catalytic subunit of phosphorylase phosphatase (protein phosphatase-1) in Escherichia coli

5 June 2018

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Familial hyperinsulinism caused by an activating glucokinase mutation

5 June 2018

1 reference

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Glucokinase and glucose homeostasis: proven concepts and new ideas

27 July 2018

1 reference

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Severe persistent hyperinsulinemic hypoglycemia due to a de novo glucokinase mutation

18 August 2018

1 reference

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Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators

18 August 2018

1 reference

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Allosteric activators of glucokinase: potential role in diabetes therapy

18 August 2018

1 reference

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The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279319

Human pancreatic glucokinase (GlkB) complements the glucose signalling defect of Saccharomyces cerevisiae hxk2 mutants

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279319

Study of the regulatory properties of glucokinase by site-directed mutagenesis: conversion of glucokinase to an enzyme with high affinity for glucose

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15987895

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1110/PS.051485205

1 reference

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13 January 2020

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13 January 2020

PubMed publication ID

15987895

1 reference

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