Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin (Q41818985)

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scientific article published on June 2000

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English	Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin	scientific article published on June 2000

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scholarly article

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6 November 2019

Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10816429%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Robert C. Stein

3

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6 November 2019

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Coulonval K

1

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6 November 2019

Vandeput F

2

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6 November 2019

Kozma SC

4

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6 November 2019

Lamy F

5

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6 November 2019

Dumont JE

6

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6 November 2019

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1 June 2000

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6 November 2019

Biochemical Journal

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6 November 2019

348 Pt 2

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6 November 2019

351-358

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6 November 2019

A simple method for the isolation and purification of total lipides from animal tissues

1 reference

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6 June 2018

Mammalian TOR controls one of two kinase pathways acting upon nPKCdelta and nPKCepsilon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

The role of the IGF-I receptor in the growth and transformation of mammalian cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Mechanism of protein kinase B activation by cyclic AMP-dependent protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Differential effects of cyclic adenosine 3',5'-monophosphate on p70 ribosomal S6 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

The dog thyroid primary culture system: a model of the regulation of function, growth and differentiation expression by cAMP and other well-defined signaling cascades

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Activation of cyclic AMP-dependent kinase is required but may not be sufficient to mimic cyclic AMP-dependent DNA synthesis and thyroglobulin expression in dog thyroid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Phosphatidylinositol 3'-kinase-independent p70 S6 kinase activation by fibroblast growth factor receptor-1 is important for proliferation but not differentiation of endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Phosphoinositide 3-kinases: A conserved family of signal transducers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

The modular phosphorylation and activation of p70s6k.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Activation of protein kinase B (Akt/RAC‐protein kinase) by cellular stress and its association with heat shock protein Hsp27

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

RalGDS functions in Ras- and cAMP-mediated growth stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Integrin-dependent activation of the p70 ribosomal S6 kinase signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Mechanism of action of the immunosuppressant rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Mitogenic, dedifferentiating, and scattering effects of hepatocyte growth factor on dog thyroid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

p70s6k/p85s6k: mechanism of activation and role in mitogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Dissociation of cAMP-stimulated Mitogenesis from Activation of the Mitogen-activated Protein Kinase Cascade in Swiss 3T3 Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Molecular and Cellular Aspects of Insulin-like Growth Factor Action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Multiple facets of the modulation of growth by cAMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Differential protein phosphorylation in induction of thyroid cell proliferation by thyrotropin, epidermal growth factor, or phorbol ester

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Identification and quantification of polyphosphoinositides produced in response to platelet-derived growth factor stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Identification and early activation of a Xenopus laevis p70s6k following progesterone-induced meiotic maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

6 June 2018

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

18 August 2018

Regulation of the p70 S6 kinase by phosphorylation in vivo. Analysis using site-specific anti-phosphopeptide antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

18 August 2018

Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221073

2 December 2018

Detection of nerve growth factor and epidermal growth factor-regulated protein kinases in PC12 cells with synthetic peptide substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate recognition determinants of the mitogen-activated 70K S6 kinase from rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of mitogen-activated protein kinases is involved in the epidermal growth factor and phorbol ester, but not in the thyrotropin/cAMP, thyroid mitogenic pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstration of cell cycle kinetics in thyroid primary culture by immunostaining of proliferating cell nuclear antigen: differences in cyclic AMP-dependent and -independent mitogenic stimulations

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IGF-1 or insulin, and the TSH cyclic AMP cascade separately control dog and human thyroid cell growth and DNA synthesis, and complement each other in inducing mitogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase signaling pathway triggered by cell swelling and involved in the activation of glycogen synthase and acetyl-CoA carboxylase in isolated rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thyrotropin via cyclic AMP induces insulin receptor expression and insulin Co-stimulation of growth and amplifies insulin and insulin-like growth factor signaling pathways in dog thyroid epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple G-protein coupling of the dog thyrotropin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of Phosphatidylinositol 3-Kinase in the Mediation of Erythropoietin-Induced Activation of p70S6k

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the three Rb protein family members is a common step of the cAMP-, the growth factor, and the phorbol ester-mitogenic cascades but is not necessary for the hypertrophy induced by insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP stimulates protein kinase B in a Wortmannin-insensitive manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum-free cell culture: a unifying approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/10816429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/0264-6021:3480351

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Europe PubMed Central

PMC publication ID

12 October 2017

10.1042/BJ3480351

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10816429%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PMC publication ID

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6 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

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6 November 2019

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