Glutamine repeats and inherited neurodegenerative diseases: molecular aspects (Q41312696)

29 September 2017

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title

Glutamine repeats and inherited neurodegenerative diseases: molecular aspects (English)

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29 September 2017

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Perutz MF

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29 September 2017

publication date

1 December 1996

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Current Opinion in Structural Biology

29 September 2017

published in

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29 September 2017

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29 September 2017

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29 September 2017

page(s)

848-858

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

29 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3' end of a transcript encoding a protein kinase family member.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

An unstable triplet repeat in a gene related to myotonic muscular dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Myotonic dystrophy mutation: an unstable CTG repeat in the 3' untranslated region of the gene

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Variation of the CGG repeat at the fragile X site results in genetic instability: Resolution of the Sherman paradox

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA)

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Survey of CAG/CTG repeats in human cDNAs representing new genes: candidates for inherited neurological disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Sequence of the murine Huntington disease gene: evidence for conservation, alternate splicing and polymorphism in a triplet (CCG) repeat [corrected]

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Comparative sequence analysis of the human and pufferfish Huntington's disease genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Inactivation of the mouse Huntington's disease gene homolog Hdh

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Widespread expression of Huntington's disease gene (IT15) protein product

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Expression of the Huntington's disease (IT15) protein product in HD patients

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Partial characterisation of murine huntingtin and apparent variations in the subcellular localisation of huntingtin in human, mouse and rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Mutational bias provides a model for the evolution of Huntington's disease and predicts a general increase in disease prevalence.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Sequence variation and size ranges of CAG repeats in the Machado-Joseph disease, spinocerebellar ataxia type 1 and androgen receptor genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Predominant neuronal expression of the gene responsible for dentatorubral-pallidoluysian atrophy (DRPLA) in rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Characterization and expression of a cDNA encoding the human androgen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor: possible pathogenetic relevance for the (CAG)n-expanded neuronopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Identification and characterization of the gene causing type 1 spinocerebellar ataxia

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Evidence for a mechanism predisposing to intergenerational CAG repeat instability in spinocerebellar ataxia type I.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

SCA1 transgenic mice: A model for neurodegeneration caused by an expanded CAG trinucleotide repeat

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Genetic studies of the lac repressor. VII. On the molecular nature of spontaneous hotspots in the lacI gene of Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Pausing of DNA synthesis in vitro at specific loci in CTG and CGG triplet repeats from human hereditary disease genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Trinucleotide repeats that expand in human disease form hairpin structures in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Hairpin properties of single-stranded DNA containing a GC-rich triplet repeat: (CTG)15.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Structure of a single-cytidine hairpin loop formed by the DNA triplet GCA

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Toxicity of expanded polyglutamine-domain proteins in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

A huntingtin-associated protein enriched in brain with implications for pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Huntington disease: new insights into the relationship between CAG expansion and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Transcriptional activation modulated by homopolymeric glutamine and proline stretches

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Trinucleotide repeats and long homopeptides in genes and proteins associated with nervous system disease and development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

1 reference

7 January 2021

Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Incorporation of glutamine repeats makes protein oligomerize: implications for neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

3D domain swapping: a mechanism for oligomer assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

Human lysozyme gene mutations cause hereditary systemic amyloidosis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

A mechanism for gene conversion in fungi

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

DNA Recombination: In Vivo and In Vitro Studies

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980016-9

7 January 2021

10.1016/S0959-440X(96)80016-9

Identifiers

DOI

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release_fuxijagolvdhnouxpvt3b36ymy

29 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/fuxijagolvdhnouxpvt3b36ymy

24 November 2022

mapped directly with Wikidata item

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