Characterization of p53 in Chinese hamster cell lines CHO-K1, CHO-WBL, and CHL: implications for genotoxicity testing (Q40955103)

25 September 2017

title

Characterization of p53 in Chinese hamster cell lines CHO-K1, CHO-WBL, and CHL: implications for genotoxicity testing (English)

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25 September 2017

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Hu T

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25 September 2017

Miller CM

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25 September 2017

Ridder GM

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25 September 2017

Aardema MJ

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25 September 2017

language of work or name

English

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publication date

1 May 1999

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25 September 2017

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25 September 2017

volume

426

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25 September 2017

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25 September 2017

page(s)

51-62

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describes a project that uses

25 September 2017

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The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis.

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Cancer. p53, guardian of the genome

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Chromosome changes caused by alterations of p53 expression

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

The p53 status of Chinese hamster V79 cells frequently used for studies on DNA damage and DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Cloning and characterization of Chinese hamster p53 cDNA.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

p53 Expression in normal versus transformed mammalian cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

The mouse lymphoma L5178Y Tk+/- cell line is heterozygous for a codon 170 mutation in the p53 tumor suppressor gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Identification and chromosomal assignment of two heterozygous mutations in the Trp53 gene in L5178Y/Tk(+/-)-3.7.2C mouse lymphoma cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

A mutation in the p53 tumor suppressor gene of AHH-1 tk+/- human lymphoblastoid cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

A comprehensive protocol for conducting the Syrian hamster embryo cell transformation assay at pH 6.70.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Mutant conformation of p53. Precise epitope mapping using a filamentous phage epitope library

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Absence of mutations in the highest mutability region of the p53 gene in tumour-derived CHEF18 Chinese hamster cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Molecular basis for heterogeneity of the human p53 protein

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

DNA damage and p53-mediated cell cycle arrest: a reevaluation.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

A role for apoptosis in the toxicity and mutagenicity of bleomycin in AHH-1 tk+/- human lymphoblastoid cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

7 January 2021

When checkpoints fail

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Cytotoxic and mutagenic responses to X-rays and chemical mutagens in normal and p53-mutated human lymphoblastoid cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Fewer chromosome aberrations and earlier apoptosis induced by DNA synthesis inhibitors, a topoisomerase II inhibitor or alkylating agents in human cells with normal compared with mutant p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

Different sensitivity to cell killing and chromosome mutation induction by gamma rays in two human lymphoblastoid cell lines derived from a single donor: possible role of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

The relationship between p53 status, DNA repair and chromatid aberration induction in G2 mouse embryo fibroblast cells treated with bleomycin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

A comparison of chromosome aberration induction by 25 compounds tested by two Chinese hamster cell (CHL and CHO) systems in culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900077-9

10.1016/S0027-5107(99)00077-9

7 January 2021

Identifiers

DOI

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25 September 2017

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