Quality control of ER synthesized proteins: an exposed thiol group as a three-way switch mediating assembly, retention and degradation. (Q40875183)

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27 October 2019

title

Quality control of ER synthesized proteins: an exposed thiol group as a three-way switch mediating assembly, retention and degradation (English)

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27 October 2019

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Fra AM

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27 October 2019

Fagioli C

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27 October 2019

Finazzi D

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27 October 2019

Sitia R

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27 October 2019

Alberini CM

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27 October 2019

language of work or name

English

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publication date

1 December 1993

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27 October 2019

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27 October 2019

volume

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27 October 2019

issue

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27 October 2019

page(s)

4755-4761

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Two crystal structures for cathepsin D: the lysosomal targeting signal and active site

27 October 2019

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1 reference

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Expression of human cathepsin D in Xenopus oocytes: phosphorylation and intracellular targeting

24 September 2017

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24 September 2017

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24 September 2017

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24 September 2017

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24 September 2017

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Regulation of protein degradation rates in eukaryotes

24 September 2017

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Intermolecular disulfide bonding in IgM: effects of replacing cysteine residues in the mu heavy chain.

24 September 2017

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Protein degradation in the endoplasmic reticulum

24 September 2017

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Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin A suggests an ER recycling pathway

24 September 2017

1 reference

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The transmembrane anchor of the T-cell antigen receptor beta chain contains a structural determinant of pre-Golgi proteolysis

24 September 2017

1 reference

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Secretion of immunoglobulin M assembly intermediates in the presence of reducing agents

24 September 2017

1 reference

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A permeabilized cell system identifies the endoplasmic reticulum as a site of protein degradation

24 September 2017

1 reference

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Distinct intracellular fates of membrane and secretory immunoglobulin heavy chains in a pre-B cell line

24 September 2017

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Role of potentially charged transmembrane residues in targeting proteins for retention and degradation within the endoplasmic reticulum

24 September 2017

1 reference

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Degradation of proteins within the endoplasmic reticulum

24 September 2017

1 reference

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J chain synthesis and secretion of hexameric IgM is differentially regulated by lipopolysaccharide and interleukin 5

24 September 2017

1 reference

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Carboxy terminally truncated forms of ribophorin I are degraded in pre-Golgi compartments by a calcium-dependent process

24 September 2017

1 reference

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Endoplasmic reticulum: a dynamic patchwork of specialized subregions

24 September 2017

1 reference

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Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors

24 September 2017

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Plasma cell immunoglobulin M molecules. Their biosynthesis, assembly, and intracellular transport

24 September 2017

1 reference

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Evidence that luminal ER proteins are sorted from secreted proteins in a post-ER compartment

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413922

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling

25 September 2017

1 reference

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Regulation of membrane IgM expression in secretory B cells: translational and post-translational events

25 September 2017

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Expression and regulation of immunoglobulin heavy chain gene transfected into lymphoid cells.

25 September 2017

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Interrelations between assembly and secretion of recombinant human acetylcholinesterase

17 June 2018

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Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight.

17 June 2018

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Polymeric immunoglobulin M is secreted by transfectants of non-lymphoid cells in the absence of immunoglobulin J chain.

17 June 2018

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Assembly and secretion of heavy chains that do not associate posttranslationally with immunoglobulin heavy chain-binding protein

17 June 2018

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Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas

17 June 2018

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Colocalized transmembrane determinants for ER degradation and subunit assembly explain the intracellular fate of TCR chains

17 June 2018

1 reference

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Transmembrane helical interactions and the assembly of the T cell receptor complex

17 June 2018

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Immunoglobulin heavy chain and binding protein complexes are dissociated in vivo by light chain addition

17 June 2018

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Developmental regulation of IgM secretion: the role of the carboxy-terminal cysteine

17 June 2018

1 reference

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Russell bodies: a general response of secretory cells to synthesis of a mutant immunoglobulin which can neither exit from, nor be degraded in, the endoplasmic reticulum

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413922

Expression and maturation of human cathepsin D in baby-hamster kidney cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413922

Degradation of secretory immunoglobulin M in B lymphocytes occurs in a postendoplasmic reticulum compartment and is mediated by a cysteine protease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413922

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413922

The spectrum of incomplete N-linked oligosaccharides synthesized by endothelial cells in the presence of brefeldin A.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413922

Toxin entry: how reversible is the secretory pathway?

19 August 2018

1 reference

12 December 2020

Translocation of TCR alpha chains into the lumen of the endoplasmic reticulum and their degradation

1 reference

12 December 2020

The endoplasmic reticulum as a protein-folding compartment

1 reference

12 December 2020

A peptide sequence confers retention and rapid degradation in the endoplasmic reticulum

1 reference

12 December 2020

Degradation from the endoplasmic reticulum: disposing of newly synthesized proteins

1 reference

12 December 2020

Intracellular processing of membrane and secreted immunoglobulin delta-chains

1 reference

12 December 2020

Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes

1 reference

12 December 2020

Procathepsin D cannot autoactivate to cathepsin D at acid pH

1 reference

12 December 2020

10.1002/J.1460-2075.1993.TB06164.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8223484%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8223484%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

PubMed publication ID

8223484

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8223484%20AND%20SRC:MED&resulttype=core&format=json