Creation of immune 'stealth' genes for gene therapy through fusion with the Gly-Ala repeat of EBNA-1. (Q40625018)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

title

Creation of immune 'stealth' genes for gene therapy through fusion with the Gly-Ala repeat of EBNA-1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

0 references

Djm van den Wollenberg

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

M Ossevoort

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

B M J Visser

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

E I H van der Voort

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

R Offringa

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

C J M Melief

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

publication date

1 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

page(s)

2020-2028

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14566361%20AND%20SRC:MED&resulttype=core&format=json

Gene therapy with recombinant adenovirus vectors: evaluation of the host immune response

20 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Recombinant adenoviral vectors have adjuvant activity and stimulate T cell responses against tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Adenovirus-mediated gene transfer: influence of transgene, mouse strain and type of immune response on persistence of transgene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Development of a preventive vaccine for Ebola virus infection in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Heterologous protection against influenza by injection of DNA encoding a viral protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Protective anti-tumor immunity induced by vaccination with recombinant adenoviruses encoding multiple tumor-associated cytotoxic T lymphocyte epitopes in a string-of-beads fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Immune response to recombinant adenovirus in humans: capsid components from viral input are targets for vector-specific cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Muscle-specific promoters may be necessary for adeno-associated virus-mediated gene transfer in the treatment of muscular dystrophies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Transient depletion of CD4 lymphocyte improves efficacy of repeated administration of recombinant adenovirus in the ornithine transcarbamylase deficient sparse fur mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Immunology of gene therapy with adenoviral vectors in mouse skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Gene transfer of a chimeric trans-activator is immunogenic and results in short-lived transgene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Viruses use stealth technology to escape from the host immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Viral strategies of immune evasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Localization of Epstein-Barr virus cytotoxic T cell epitopes using recombinant vaccinia: implications for vaccine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Isolation of cytotoxic T lymphocytes from healthy seropositive individuals specific for peptide epitopes from Epstein-Barr virus nuclear antigen 1: implications for viral persistence and tumor surveillance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Human CD4(+) T lymphocytes consistently respond to the latent Epstein-Barr virus nuclear antigen EBNA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

The importance of exogenous antigen in priming the human CD8+ T cell response: lessons from the EBV nuclear antigen EBNA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Human cytotoxic T lymphocyte responses to Epstein-Barr virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Inhibition of antigen processing by the internal repeat region of the Epstein-Barr virus nuclear antigen-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein-Barr virus nuclear antigen 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

A minimal glycine-alanine repeat prevents the interaction of ubiquitinated I kappaB alpha with the proteasome: a new mechanism for selective inhibition of proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

cis-Inhibition of proteasomal degradation by viral repeats: impact of length and amino acid composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Inhibition of proteasomal degradation by the gly-Ala repeat of Epstein-Barr virus is influenced by the length of the repeat and the strength of the degradation signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Targeting of EBNA1 for rapid intracellular degradation overrides the inhibitory effects of the Gly-Ala repeat domain and restores CD8+ T cell recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Functional p53 chimeras containing the Epstein-Barr virus Gly-Ala repeat are protected from Mdm2- and HPV-E6-induced proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Adenovirus vectors for gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

A simplified system for generating recombinant adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Characterization of 911: a new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

New helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Specific tumor-cell killing with adenovirus vectors containing the apoptin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Isolated-organ perfusion for local gene delivery: efficient adenovirus-mediated gene transfer into the liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Severe hepatic dysfunction after adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene and ganciclovir administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Elimination of the truncated message from the herpes simplex virus thymidine kinase suicide gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

Transduction of dendritic cells by DNA viral vectors directs the immune response to transgene products in muscle fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

7 January 2021

Long-term humoral and cellular immunity induced by a single immunization with replication-defective adenovirus recombinant vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

7 January 2021

Role of viral antigens in destructive cellular immune responses to adenovirus vector-transduced cells in mouse lungs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

7 January 2021

Persistence of Replication-Deficient Adenovirus-Mediated Gene Transfer in Lungs of Immune-Deficient (nu/nu) Mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

7 January 2021

Use of transient CD4 lymphocyte depletion to prolong transgene expression of E1-deleted adenoviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

7 January 2021

Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

7 January 2021

Human CD8+ T cell responses to EBV EBNA1: HLA class I presentation of the (Gly-Ala)-containing protein requires exogenous processing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

7 January 2021

Inactivation of the Moloney murine leukemia virus long terminal repeat in murine fibroblast cell lines is associated with methylation and dependent on its chromosomal position

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302098

7 January 2021