Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. (Q40477651)

20 September 2017

title

Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. (English)

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20 September 2017

Christian Wolfrum

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20 September 2017

Esra Asilmaz

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20 September 2017

Edlira Luca

series ordinal

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20 September 2017

Jeffrey M Friedman

series ordinal

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20 September 2017

Markus Stoffel

series ordinal

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20 September 2017

language of work or name

English

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publication date

1 December 2004

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20 September 2017

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20 September 2017

volume

432

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20 September 2017

issue

7020

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20 September 2017

page(s)

1027-1032

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Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.

20 September 2017

cites work

1 reference

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Ketone bodies: a review of physiology, pathophysiology and application of monitoring to diabetes

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Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes

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Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes

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The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

1 reference

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7 January 2021

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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7 January 2021

Inhibition of Foxo1 function is associated with improved fasting glycemia in diabetic mice

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7 January 2021

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

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7 January 2021

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

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7 January 2021

Inhibition of the mitochondrial oxidation of fatty acids by tetracycline in mice and in man: Possible role in microvesicular steatosis induced by this antibiotic

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7 January 2021

The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo

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7 January 2021

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

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7 January 2021

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

1 reference

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7 January 2021

Regulation of the gene expression of glucokinase and L-type pyruvate kinase in primary cultures of rat hepatocytes by hormones and carbohydrates

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7 January 2021

Transcriptional control of metabolic regulation genes by carbohydrates.

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7 January 2021

Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion

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7 January 2021

Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance

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7 January 2021

Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice

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7 January 2021

The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism

1 reference

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7 January 2021

The coactivator PGC-1 is involved in the regulation of the liver carnitine palmitoyltransferase I gene expression by cAMP in combination with HNF4 alpha and cAMP-response element-binding protein (CREB)

1 reference

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7 January 2021

Role of peroxisome proliferator-activated receptor-gamma in the glucose-sensing apparatus of liver and beta-cells

1 reference

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7 January 2021

Preparation of transcriptionally active nuclear extracts from mammalian tissues

1 reference

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7 January 2021

Hepatocyte Nuclear Factor-3 (HNF-3) Binds to the Insulin Response Sequence in the IGF Binding Protein-1 (IGFBP-1) Promoter and Enhances Promoter Function

1 reference

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7 January 2021

Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism

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7 January 2021

Mechanism of insulin resistance in fructose-fed rats

1 reference

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7 January 2021

Identifiers

DOI

10.1038/NATURE03047

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Dimensions Publication ID

20 September 2017

1027801544

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1 reference