Clostridium difficile toxin A regulates inducible cyclooxygenase-2 and prostaglandin E2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAPK. (Q40446906)

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English	Clostridium difficile toxin A regulates inducible cyclooxygenase-2 and prostaglandin E2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAPK.	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Clostridium difficile toxin A regulates inducible cyclooxygenase-2 and prostaglandin E2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAPK. (English)

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Europe PubMed Central

PubMed publication ID

20 September 2017

Clostridium difficile

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reactive oxygen species

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based on heuristic

inferred from title

prostaglandin E2

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based on heuristic

inferred from title

6

object named as

Mary P Moyer

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Europe PubMed Central

PubMed publication ID

20 September 2017

author name string

Ho Kim

1

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Europe PubMed Central

PubMed publication ID

20 September 2017

Sang Hoon Rhee

2

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Europe PubMed Central

PubMed publication ID

20 September 2017

Efi Kokkotou

3

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Europe PubMed Central

PubMed publication ID

20 September 2017

Xi Na

4

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Europe PubMed Central

PubMed publication ID

20 September 2017

Tor Savidge

5

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Charalabos Pothoulakis

7

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Europe PubMed Central

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20 September 2017

J Thomas LaMont

8

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Europe PubMed Central

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20 September 2017

language of work or name

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publication date

14 March 2005

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Europe PubMed Central

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20 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

20 September 2017

280

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Europe PubMed Central

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20 September 2017

22

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Europe PubMed Central

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20 September 2017

21237-21245

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Europe PubMed Central

PubMed publication ID

20 September 2017

Clostridium difficile colitis

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https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Toxins A and B from Clostridium difficile differ with respect to enzymatic potencies, cellular substrate specificities, and surface binding to cultured cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Essential involvement of IFN-gamma in Clostridium difficile toxin A-induced enteritis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Clostridium difficile toxin B is more potent than toxin A in damaging human colonic epithelium in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

p38 MAP kinase activation by Clostridium difficile toxin A mediates monocyte necrosis, IL-8 production, and enteritis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Rabbit sucrase-isomaltase contains a functional intestinal receptor for Clostridium difficile toxin A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Clostridium difficile toxin A triggers human colonocyte IL-8 release via mitochondrial oxygen radical generation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Effect of Clostridium difficile toxin A on human intestinal epithelial cells: induction of interleukin 8 production and apoptosis after cell detachment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Role of inducible cyclooxygenase and prostaglandins in Clostridium difficile toxin A-induced secretion and inflammation in an animal model

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Transcriptional regulation of cyclooxygenase 2 by bradykinin and interleukin-1beta in human airway smooth muscle cells: involvement of different promoter elements, transcription factors, and histone h4 acetylation.

1 reference

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21 January 2018

Lipopolysaccharide-induced increase of prostaglandin E(2) is mediated by inducible nitric oxide synthase activation of the constitutive cyclooxygenase and induction of membrane-associated prostaglandin E synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Role of intestinal epithelial cells in the host secretory response to infection by invasive bacteria. Bacterial entry induces epithelial prostaglandin h synthase-2 expression and prostaglandin E2 and F2alpha production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Clostridium difficile toxin B is an inflammatory enterotoxin in human intestine.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Signal transduction pathways mediating neurotensin-stimulated interleukin-8 expression in human colonocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Quantification of mRNA by non-radioactive RT-PCR and CCD imaging system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Human intestinal development in a severe-combined immunodeficient xenograft model.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Ceramide-induced and age-associated increase in macrophage COX-2 expression is mediated through up-regulation of NF-kappa B activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Aspirin-mediated COX-2 transcript stabilization via sustained p38 activation in human intestinal myofibroblasts

1 reference

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21 January 2018

Transactivation of the human renin promoter by the cyclic AMP/protein kinase A pathway is mediated by both cAMP-responsive element binding protein-1 (CREB)-dependent and CREB-independent mechanisms in Calu-6 cells

1 reference

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21 January 2018

Proliferation of hepatic stellate cells is inhibited by phosphorylation of CREB on serine 133.

1 reference

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UV induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal C1 41 cells through hydrogen peroxide

1 reference

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21 January 2018

Differential role of hydrogen peroxide in UV-induced signal transduction

1 reference

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21 January 2018

Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413842200

21 January 2018

Role of cyclic AMP responsive element in the UVB induction of cyclooxygenase-2 transcription in human keratinocytes

1 reference

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21 January 2018

Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells

1 reference

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21 January 2018

Inhibition of prostaglandin-induced intestinal secretion by igmesine in healthy volunteers.

1 reference

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21 January 2018

Chloride secretory mechanism induced by prostaglandin E1 in a colonic epithelial cell line

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M413842200

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

ResearchGate publication ID

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