The tyrosine kinase pyk2 promotes migration and invasion of glioma cells. (Q40407170)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15967096%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

title

The tyrosine kinase pyk2 promotes migration and invasion of glioma cells (English)

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13 January 2020

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13 January 2020

author name string

Christopher A Lipinski

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13 January 2020

Nhan L Tran

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13 January 2020

Emmanuel Menashi

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13 January 2020

Carole Rohl

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13 January 2020

Jean Kloss

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13 January 2020

Michael E Berens

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13 January 2020

Joseph C Loftus

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13 January 2020

publication date

1 May 2005

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13 January 2020

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13 January 2020

volume

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13 January 2020

issue

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13 January 2020

page(s)

435-445

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FERM domain interaction promotes FAK signaling

13 January 2020

cites work

1 reference

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Pyk2 amplifies epidermal growth factor and c-Src-induced Stat3 activation

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Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration

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Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression

22 September 2017

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Glioma cell motility is associated with reduced transcription of proapoptotic and proliferation genes: a cDNA microarray analysis

22 September 2017

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Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase

22 September 2017

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Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade

22 September 2017

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Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cells

22 September 2017

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Integrin cytoplasmic domain-binding proteins

22 September 2017

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Temozolomide and treatment of malignant glioma.

22 September 2017

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RAFTK/Pyk2-mediated cellular signalling

22 September 2017

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ERM proteins in cell adhesion and membrane dynamics

22 September 2017

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The N-termini of FAK and JAKs contain divergent band 4.1 domains

22 September 2017

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Regulation of the cell cycle by focal adhesion kinase

22 September 2017

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Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

22 September 2017

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PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation of alpha(v)beta3 integrin, and phosphorylated by src kinase

22 September 2017

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Integrin-mediated signal transduction in cells lacking focal adhesion kinase p125FAK.

22 September 2017

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A simplified system for generating recombinant adenoviruses

22 September 2017

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Integrins: emerging paradigms of signal transduction

22 September 2017

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22 September 2017

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

22 September 2017

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Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain

22 September 2017

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22 September 2017

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The assessment of cellular proliferation by immunohistochemistry: a review of currently available methods and their applications

22 September 2017

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Inhibition of PYK2-induced actin cytoskeleton reorganization, PYK2 autophosphorylation and focal adhesion targeting by FAK.

22 September 2017

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Pyk2 and FAK differentially regulate progression of the cell cycle.

25 September 2017

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25 September 2017

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Diffuse brain invasion of glioma cells requires beta 1 integrins

25 September 2017

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Stimulation of glioma-cell migration by laminin and inhibition by anti-alpha3 and anti-beta1 integrin antibodies

25 September 2017

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Signal transduction from the extracellular matrix--a role for the focal adhesion protein-tyrosine kinase FAK.

25 September 2017

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Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily

25 September 2017

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Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis

25 September 2017

1 reference

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BCL-2 promotes migration and invasiveness of human glioma cells

17 June 2018

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Basement membrane invasion of glioma cells mediated by integrin receptors

17 June 2018

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Expression of tyrosine kinases FAK and Pyk2 in 331 human astrocytomas

17 June 2018

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Vascular endothelial growth factor regulates focal adhesion assembly in human brain microvascular endothelial cells through activation of the focal adhesion kinase and related adhesion focal tyrosine kinase

20 August 2018

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Differential role of proline-rich tyrosine kinase 2 and focal adhesion kinase in determining glioblastoma migration and proliferation

20 August 2018

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Suppression of Rac activity induces apoptosis of human glioma cells but not normal human astrocytes.

20 August 2018

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Molecular determinants of glioma cell migration and invasion

20 August 2018

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Inhibition of osteoclast function by adenovirus expressing antisense protein-tyrosine kinase 2.

20 August 2018

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p125 focal adhesion kinase promotes malignant astrocytoma cell proliferation in vivo.

20 August 2018

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A novel model of glioma cell invasion using organotypic brain slice culture

20 August 2018

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Integrin alpha3beta1-mediated interaction with laminin-5 stimulates adhesion, migration and invasion of malignant glioma cells.

20 August 2018

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Dichotomy of astrocytoma migration and proliferation.

20 August 2018

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Determinants of human astrocytoma migration

20 August 2018

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Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors

20 August 2018

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12 December 2020

Focal adhesion kinase and its potential involvement in tumor invasion and metastasis

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12 December 2020

Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases

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Inhibition of the calcium-dependent tyrosine kinase (CADTK) blocks monocyte spreading and motility

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12 December 2020

Identifiers

DOI

10.1593/NEO.04712

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15967096%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15967096%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

PubMed publication ID

15967096

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15967096%20AND%20SRC:MED&resulttype=core&format=json