Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis (Q38290076)

1 September 2017

title

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis (English)

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1 September 2017

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Guilian Niu

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1 September 2017

Kenneth L Wright

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1 September 2017

Mei Huang

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1 September 2017

Lanxi Song

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1 September 2017

Eric Haura

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1 September 2017

James Turkson

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1 September 2017

Shumin Zhang

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1 September 2017

Tianhong Wang

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1 September 2017

Dominic Sinibaldi

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1 September 2017

Domenico Coppola

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1 September 2017

Richard Heller

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1 September 2017

Lee M Ellis

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1 September 2017

James Karras

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1 September 2017

Jacqueline Bromberg

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1 September 2017

Drew Pardoll

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1 September 2017

Richard Jove

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1 September 2017

Hua Yu

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1 September 2017

language of work or name

English

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publication date

1 March 2002

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1 September 2017

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1 September 2017

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1 September 2017

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1 September 2017

page(s)

2000-2008

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Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

1 September 2017

cites work

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Stat3 activation is required for cellular transformation by v-src

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STAT proteins as novel targets for cancer therapy. Signal transducer an activator of transcription

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

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Tumor cell responses to IFNgamma affect tumorigenicity and response to IL-12 therapy and antiangiogenesis

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Site-directed mutagenesis of virtually any plasmid by eliminating a unique site

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Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfected with an antisense expression vector specific for c-src

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Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis

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Signal transducer and activator of transcription 3 is required for glycoprotein 130-mediated induction of vascular endothelial growth factor in cardiac myocytes

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Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

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Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro

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Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

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Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells

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EGF receptor in neoplasia and metastasis

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Involvement of pp60c-src with two major signaling pathways in human breast cancer

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Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src

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Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

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Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

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Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

21 January 2018

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Oncogenes and angiogenesis: signaling three-dimensional tumor growth

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Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

21 January 2018

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Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling

21 January 2018

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Stat3 activation by Src induces specific gene regulation and is required for cell transformation

21 January 2018

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STAT proteins: novel molecular targets for cancer drug discovery

21 January 2018

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Target gene specificity of E2F and pocket protein family members in living cells

21 January 2018

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Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain

21 January 2018

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Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

21 January 2018

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STAT3 participates in transcriptional activation of the C-reactive protein gene by interleukin-6.

21 January 2018

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STAT3beta, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription

21 January 2018

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7 January 2021

Signaling angiogenesis via p42/p44 MAP kinase cascade

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7 January 2021

Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity

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7 January 2021

beta-Thymosins are not simple actin monomer buffering proteins. Insights from overexpression studies

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205260

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Dimensions Publication ID

1 September 2017

1006935562

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