HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals (Q37771138)

22 August 2017

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title

HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals (English)

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22 August 2017

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22 August 2017

Christine Rouzioux

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Françoise Barré-Sinoussi

series ordinal

object named as

Françoise Barré-Sinoussi

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Carine Van Lint

series ordinal

object named as

Carine Van Lint

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Nicolas Chomont

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Tae-Wook Chun

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22 August 2017

Didier Trono

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22 August 2017

language of work or name

English

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publication date

1 July 2010

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22 August 2017

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22 August 2017

volume

329

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22 August 2017

issue

5988

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22 August 2017

page(s)

174-180

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Current status and challenges of antiretroviral research and therapy

22 August 2017

cites work

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https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Redefining chronic viral infection

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Towards an understanding of the molecular basis of herpes simplex virus latency

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Immunobiology and pathogenesis of viral hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

HIV-infected individuals receiving effective antiviral therapy for extended periods of time continually replenish their viral reservoir

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Relationship between human immunodeficiency virus type 1 (HIV-1)-specific memory cytotoxic T lymphocytes and virus load after recent HIV-1 seroconversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Decay characteristics of HIV-1-infected compartments during combination therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Modeling HIV persistence, the latent reservoir, and viral blips

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Kinetics of human immunodeficiency virus type 1 decay following entry into resting CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

A role for LEDGF/p75 in targeting HIV DNA integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

CpG methylation controls reactivation of HIV from latency

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Epigenetic regulation of HIV-1 latency by cytosine methylation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Interfering RNA and HIV: reciprocal interferences

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

CD8+ T lymphocytes of patients with AIDS maintain normal broad cytolytic function despite the loss of human immunodeficiency virus-specific cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

HIV preferentially infects HIV-specific CD4+ T cells

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Skewed maturation of memory HIV-specific CD8 T lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Suppression of HIV replication in the resting CD4+ T cell reservoir by autologous CD8+ T cells: implications for the development of therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Central memory CD8+ T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Antiviral therapy during primary simian immunodeficiency virus infection fails to prevent acute loss of CD4+ T cells in gut mucosa but enhances their rapid restoration through central memory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Distinct genetic loci control plasma HIV-RNA and cellular HIV-DNA levels in HIV-1 infection: the ANRS Genome Wide Association 01 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

HIV rebounds from latently infected cells, rather than from continuing low-level replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Relationship between pre-existing viral reservoirs and the re-emergence of plasma viremia after discontinuation of highly active anti-retroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Intensification of a triple-nucleoside regimen with tenofovir or efavirenz in HIV-1-infected patients with virological suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Short-course raltegravir intensification does not reduce persistent low-level viremia in patients with HIV-1 suppression during receipt of combination antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Hide-and-seek: the challenge of viral persistence in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

IL-7 is a potent and proviral strain-specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Depletion of latent HIV-1 infection in vivo: a proof-of-concept study

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Stability of the latent reservoir for HIV-1 in patients receiving valproic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Antiretroviral intensification and valproic acid lack sustained effect on residual HIV-1 viremia or resting CD4+ cell infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

KAP1 controls endogenous retroviruses in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Targeting early infection to prevent HIV-1 mucosal transmission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Adaptation of HIV-1 to human leukocyte antigen class I

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Safety and immunogenicity of therapeutic DNA vaccination in individuals treated with antiretroviral therapy during acute/early HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Elucidating the elite: mechanisms of control in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Immunology and the elusive AIDS vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1191047

Direct Observation of Vortex Dynamics in Superconducting Films with Regular Arrays of Defects

21 January 2018

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1191047

Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1191047

Functional and phenotypic evidence for a selective loss of memory T cells in asymptomatic human immunodeficiency virus-infected men

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1191047

Control of SIV rebound through structured treatment interruptions during early infection

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1191047

Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1191047

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1191047

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1191047

Prognosis in HIV-1 infection predicted by the quantity of virus in plasma

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1191047

The duration of exposure to HIV modulates the breadth and the magnitude of HIV-specific memory CD4+ T cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1191047

Genetic characterization of rebounding HIV-1 after cessation of highly active antiretroviral therapy

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1191047

The gastrointestinal tract and AIDS pathogenesis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1191047

HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1191047

Identifiers

DOI

10.1126/SCIENCE.1191047

1 reference

22 August 2017

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