p53 is balancing development, differentiation and de-differentiation to assure cancer prevention. (Q37760978)

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3 February 2020

review article

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title

p53 is balancing development, differentiation and de-differentiation to assure cancer prevention (English)

1 reference

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3 February 2020

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3 February 2020

Varda Rotter

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3 February 2020

Rachel Sarig

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3 February 2020

Alina Molchadsky

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3 February 2020

Noa Rivlin

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3 February 2020

language of work or name

English

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publication date

26 May 2010

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3 February 2020

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3 February 2020

volume

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3 February 2020

issue

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3 February 2020

page(s)

1501-1508

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Cancer. p53, guardian of the genome

3 February 2020

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p53 associates with trk tyrosine kinase

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Mediation of nerve growth factor-driven cell cycle arrest in PC12 cells by p53. Simultaneous differentiation and proliferation subsequent to p53 functional inactivation

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NGF-mediated transcriptional targets of p53 in PC12 neuronal differentiation

21 January 2018

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p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

21 January 2018

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Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model

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p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling

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Absence of the p53 tumor suppressor gene promotes osteogenesis in mesenchymal stem cells

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p53 regulates the proliferation, differentiation and spontaneous transformation of mesenchymal stem cells.

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The p53 family inhibitor DeltaNp73 interferes with multiple developmental programs.

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p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner

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Involvement of wild-type p53 in pre-B-cell differentiation in vitro

21 January 2018

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Growth suppression of Friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erythropoietin

21 January 2018

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The glucocorticoid receptor is required for stress erythropoiesis

21 January 2018

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The p53 tumour suppressor inhibits glucocorticoid-induced proliferation of erythroid progenitors.

21 January 2018

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Comparative, genome-scale transcriptional analysis of CHRF-288-11 and primary human megakaryocytic cell cultures provides novel insights into lineage-specific differentiation

21 January 2018

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Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosis

21 January 2018

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Differential expression of novel potential regulators in hematopoietic stem cells

21 January 2018

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p53 regulates hematopoietic stem cell quiescence.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance.

21 January 2018

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p53 Activation in Adipocytes of Obese Mice

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21 January 2018

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21 January 2018

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p53 regulates mitochondrial respiration

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A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

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Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

21 January 2018

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The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells.

21 January 2018

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The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior

21 January 2018

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Hematopoietic stem cell quiescence: yet another role for p53.

21 January 2018

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Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma

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p53 suppresses the self-renewal of adult neural stem cells.

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Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19ARF-p53 pathway

21 January 2018

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p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

21 January 2018

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Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells.

21 January 2018

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Generation of pluripotent stem cells from neonatal mouse testis

21 January 2018

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The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter

21 January 2018

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Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage

21 January 2018

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Direct cell reprogramming is a stochastic process amenable to acceleration

21 January 2018

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Stem cells: The promises and perils of p53.

21 January 2018

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Mouse fibroblasts lacking RB1 function form spheres and undergo reprogramming to a cancer stem cell phenotype

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Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

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Nanog transforms NIH3T3 cells and targets cell-type restricted genes

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Nanog inhibits the switch of myogenic cells towards the osteogenic lineage

21 January 2018

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Lin28 promotes transformation and is associated with advanced human malignancies

21 January 2018

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An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

21 January 2018

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Module map of stem cell genes guides creation of epithelial cancer stem cells

21 January 2018

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Stem cells, cancer, and cancer stem cells

21 January 2018

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Cancer stem cells: mirage or reality?

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

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Prospective identification of tumorigenic breast cancer cells

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Skeletons in the p53 tumor suppressor closet: genetic evidence that p53 blocks bone differentiation and development

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Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation

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