Cell penetrating peptides: overview and applications to the delivery of oligonucleotides (Q37629659)

21 August 2017

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title

Cell penetrating peptides: overview and applications to the delivery of oligonucleotides (English)

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21 August 2017

F Said Hassane

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21 August 2017

A F Saleh

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21 August 2017

R Abes

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21 August 2017

M J Gait

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21 August 2017

Bernard Lebleu

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21 August 2017

publication date

7 November 2009

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Cellular and Molecular Life Sciences

21 August 2017

published in

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21 August 2017

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21 August 2017

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21 August 2017

page(s)

715-726

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TAT-liposomes: a novel intracellular drug carrier

21 August 2017

cites work

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12 December 2020

TAT-BH4 counteracts Abeta toxicity on capillary endothelium

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12 December 2020

Tumor imaging by means of proteolytic activation of cell-penetrating peptides

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12 December 2020

Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins

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Impaired perfusion after myocardial infarction is due to reperfusion-induced deltaPKC-mediated myocardial damage

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12 December 2020

Arginine-based molecular transporters: the synthesis and chemical evaluation of releasable taxol-transporter conjugates

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12 December 2020

The design of guanidinium-rich transporters and their internalization mechanisms.

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12 December 2020

PTD-mediated delivery of anti-cell death proteins/peptides and therapeutic enzymes

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12 December 2020

Up-regulation of luciferase gene expression with antisense oligonucleotides: implications and applications in functional assay development

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12 December 2020

OVCAR-3 cells internalize TAT-peptide modified liposomes by endocytosis

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12 December 2020

Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer

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12 December 2020

The third helix of the Antennapedia homeodomain translocates through biological membranes.

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12 December 2020

Physico-chemical requirements for cellular uptake of pAntp peptide. Role of lipid-binding affinity

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12 December 2020

Cationic TAT peptide transduction domain enters cells by macropinocytosis.

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12 December 2020

Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors.

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12 December 2020

Macrocyclic chelators with paramagnetic cations are internalized into mammalian cells via a HIV-tat derived membrane translocation peptide

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12 December 2020

High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates

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12 December 2020

Cell-penetrating peptides in drug development: enabling intracellular targets

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12 December 2020

Cell penetration by transportan.

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12 December 2020

Protein transduction domain of HIV-1 Tat protein promotes efficient delivery of DNA into mammalian cells

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12 December 2020

Cargo delivery kinetics of cell-penetrating peptides

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12 December 2020

A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.

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12 December 2020

Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs

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12 December 2020

On the biomedical promise of cell penetrating peptides: limits versus prospects

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12 December 2020

Usefulness of cell-penetrating peptides to improve intestinal insulin absorption

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12 December 2020

Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse

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12 December 2020

Novel peptide inhibitors of Leishmania gp63 based on the cleavage site of MARCKS (myristoylated alanine-rich C kinase substrate)-related protein

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12 December 2020

Cytoplasmic and nuclear delivery of a TAT-derived peptide and a beta-peptide after endocytic uptake into HeLa cells.

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12 December 2020

A new peptide vector for efficient delivery of oligonucleotides into mammalian cells.

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12 December 2020

Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models

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12 December 2020

Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis.

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12 December 2020

Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study

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12 December 2020

Protein/peptide transduction domains: potential to deliver large DNA molecules into cells.

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12 December 2020

Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies.

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12 December 2020

Antennapedia and HIV transactivator of transcription (TAT) "protein transduction domains" promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans.

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12 December 2020

Tat-mediated delivery of heterologous proteins into cells

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12 December 2020

Photochemically induced gene silencing using PNA-peptide conjugates

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12 December 2020

Homeoproteins as natural Penetratin cargoes with signaling properties

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12 December 2020

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

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12 December 2020

The topological role of homeoproteins in the developing central nervous system.

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12 December 2020

In vivo protein transduction: delivery of a biologically active protein into the mouse

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12 December 2020

Multifunctional magnetic nanoparticles for targeted imaging and therapy

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12 December 2020

Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

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12 December 2020

Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein

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12 December 2020

Novel Tat-Peptide Chelates for Direct Transduction of Technetium-99m and Rhenium into Human Cells for Imaging and Radiotherapy

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12 December 2020

A stearylated CPP for delivery of splice correcting oligonucleotides using a non-covalent co-incubation strategy

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12 December 2020

Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer

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12 December 2020

Efficient splicing correction by PNA conjugation to an R6-Penetratin delivery peptide

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12 December 2020

Positively charged DNA-binding proteins cause apparent cell membrane translocation

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12 December 2020

Polyarginine enters cells more efficiently than other polycationic homopolymers

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12 December 2020

HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responses

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12 December 2020

A Comprehensive Model for the Cellular Uptake of Cationic Cell-penetrating Peptides

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12 December 2020

Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters

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12 December 2020

Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo

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12 December 2020

TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors

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12 December 2020

Cell entry of arginine-rich peptides is independent of endocytosis

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12 December 2020

Cell-penetrating peptides: from molecular mechanisms to therapeutics.

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12 December 2020

Translocation of liposomes into cancer cells by cell-penetrating peptides penetratin and tat: a kinetic and efficacy study

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12 December 2020

Biological barriers to therapy with antisense and siRNA oligonucleotides

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12 December 2020

Local dystrophin restoration with antisense oligonucleotide PRO051

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12 December 2020

Endosome trapping limits the efficiency of splicing correction by PNA-oligolysine conjugates

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12 December 2020

Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function.

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12 December 2020

Morpholino oligomer-mediated exon skipping averts the onset of dystrophic pathology in the mdx mouse

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12 December 2020

Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans-activation in cells

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12 December 2020

Recent Developments in Peptide-Based Nucleic Acid Delivery

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12 December 2020

BH4 peptide derivative from Bcl-xL attenuates ischemia/reperfusion injury thorough anti-apoptotic mechanism in rat hearts

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12 December 2020

Molecular transporters: synthesis of oligoguanidinium transporters and their application to drug delivery and real-time imaging.

1 reference

12 December 2020

Antisense-mediated exon skipping: a versatile tool with therapeutic and research applications

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12 December 2020

Improved cell-penetrating peptide-PNA conjugates for splicing redirection in HeLa cells and exon skipping in mdx mouse muscle.

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12 December 2020

Photochemically enhanced cellular delivery of cell penetrating peptide-PNA conjugates

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12 December 2020

Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake

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12 December 2020

alpha-2,8-Polysialic acid is the neuronal surface receptor of antennapedia homeobox peptide

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12 December 2020

Cell penetrating peptide conjugates of steric block oligonucleotides

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12 December 2020

Protein kinase C delta mediates cerebral reperfusion injury in vivo.

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12 December 2020

Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents.

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12 December 2020

Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth

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12 December 2020

Translocation of the pAntp peptide and its amphipathic analogue AP-2AL.

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12 December 2020

Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers

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12 December 2020

Cell penetrating peptides for in vivo molecular imaging applications.

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12 December 2020

Arginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular uptake

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12 December 2020

Arginine-rich cell penetrating peptides: design, structure-activity, and applications to alter pre-mRNA splicing by steric-block oligonucleotides.

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12 December 2020

Tat peptide as an efficient molecule to translocate gold nanoparticles into the cell nucleus.

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12 December 2020

Modification of splicing in the dystrophin gene in cultured Mdx muscle cells by antisense oligoribonucleotides

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12 December 2020

Protein transduction revisited: novel insights into the mechanism underlying intracellular delivery of proteins

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12 December 2020

Dystrophin expression in the mdx mouse after localised and systemic administration of a morpholino antisense oligonucleotide

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12 December 2020

The 104-123 amino acid sequence of the beta-domain of von Hippel-Lindau gene product is sufficient to inhibit renal tumor growth and invasion.

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12 December 2020

Cellular uptake of the tat protein from human immunodeficiency virus

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12 December 2020

Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice.

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12 December 2020

Cellular uptake of an alpha-helical amphipathic model peptide with the potential to deliver polar compounds into the cell interior non-endocytically

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12 December 2020

Influence of protein transduction domains on intracellular delivery of macromolecules

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12 December 2020

Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation

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12 December 2020

Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles

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12 December 2020

TAT peptide-based micelle system for potential active targeting of anti-cancer agents to acidic solid tumors

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12 December 2020

Calcium ions effectively enhance the effect of antisense peptide nucleic acids conjugated to cationic tat and oligoarginine peptides

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12 December 2020

Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery

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12 December 2020

Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery

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12 December 2020

Application of novel solid lipid nanoparticle (SLN)-gene vector formulations based on a dimeric HIV-1 TAT-peptide in vitro and in vivo.

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12 December 2020

10.1007/S00018-009-0186-0

Identifiers

DOI

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21 August 2017

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