Human LilrB2 is a β-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model (Q37368308)

20 August 2017

Human LilrB2 is a β-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model (English)

1 reference

Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1

20 August 2017

0 references

1 reference

Presenilin 1

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Leukocyte immunoglobulin-like receptor subfamily B member 2

1 reference

Leukocyte immunoglobulin-like receptor subfamily B member 3

1 reference

Cofilin 1

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Leukocyte immunoglobulin like receptor B1

1 reference

Amyloid beta precursor protein

1 reference

amyloid-beta binding

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Paired Ig-like receptor B

1 reference

Protein tyrosine phosphatase, non-receptor type 11

1 reference

Cofilin 1, non-muscle

1 reference

1 reference

0 references

0 references

Christopher M William

0 references

Bradley T Hyman

1 reference

20 August 2017

Carla J Shatz

1 reference

20 August 2017

Taeho Kim

1 reference

20 August 2017

Maja Djurisic

series ordinal

1 reference

20 August 2017

K Christopher Garcia

series ordinal

1 reference

20 August 2017

language of work or name

English

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publication date

1 September 2013

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20 August 2017

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inferred from page(s)

published in

Science

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20 August 2017

341

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20 August 2017

6152

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20 August 2017

1399-1404

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FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer's disease

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Thy1-hAPP(Lond/Swe+) mouse model of Alzheimer's disease displays broad behavioral deficits in sensorimotor, cognitive and social function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Neuroglial expression of the MHCI pathway and PirB receptor is upregulated in the hippocampus with advanced aging

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Synapses and Alzheimer's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Neuroprotection from stroke in the absence of MHCI or PirB.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Paired immunoglobin-like receptor-B regulates the suppressive function and fate of myeloid-derived suppressor cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Myelin suppresses axon regeneration by PIR-B/SHP-mediated inhibition of Trk activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Amyloid-β Oligomer Specificity Mediated by the IgM Isotype – Implications for a Specific Protective Mechanism Exerted by Endogenous Auto-Antibodies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Oligodendrocyte-myelin glycoprotein and Nogo negatively regulate activity-dependent synaptic plasticity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

ALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2A

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Learning, AMPA receptor mobility and synaptic plasticity depend on n-cofilin-mediated actin dynamics.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Bidirectional synaptic mechanisms of ocular dominance plasticity in visual cortex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Deprivation-induced synaptic depression by distinct mechanisms in different layers of mouse visual cortex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

PirB restricts ocular-dominance plasticity in visual cortex.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

A specific amyloid-beta protein assembly in the brain impairs memory

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Experience-driven plasticity of visual cortex limited by myelin and Nogo receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Paired immunoglobulin-like receptors and their MHC class I recognition

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

APP processing and synaptic function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Actin depolymerizing factor and cofilin phosphorylation dynamics: response to signals that regulate neurite extension

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Synaptic plasticity defect following visual deprivation in Alzheimer's disease model transgenic mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Reduced spine density in specific regions of CA1 pyramidal neurons in two transgenic mouse models of Alzheimer's disease.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

The prion protein as a receptor for amyloid-beta.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Pyruvate prevents the inhibition of the long-term potentiation induced by amyloid-β through protein phosphatase 2A inactivation

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

PirB is a functional receptor for myelin inhibitors of axonal regeneration

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Widespread changes in dendritic spines in a model of Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3853120

Co-expression of multiple transgenes in mouse CNS: a comparison of strategies

2 September 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1242077

Protection against beta-amyloid-induced apoptosis by peptides interacting with beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1242077

NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1242077

Nucleofection and primary culture of embryonic mouse hippocampal and cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1242077

Detecting aβ*56 oligomers in brain tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1242077

mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1242077

Preparation of oligomeric beta-amyloid 1-42 and induction of synaptic plasticity impairment on hippocampal slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1242077

Multiple periods of functional ocular dominance plasticity in mouse visual cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1242077

The p75 receptor mediates axon growth inhibition through an association with PIR-B

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1242077

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1242077

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

24052308

1 reference