Nucleocytoplasmic shuttling of Smad proteins (Q37359956)

19 August 2017

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title

Nucleocytoplasmic shuttling of Smad proteins (English)

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Gene Ontology release 2020-05-02

19 August 2017

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1 reference

Gene Ontology release 2020-05-02

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Gene Ontology release 2020-05-02

Caroline S Hill

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1 January 2009

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19 August 2017

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19 August 2017

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19 August 2017

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19 August 2017

page(s)

36-46

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https://api.crossref.org/works/10.1038%2FCR.2008.325

19 August 2017

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7 January 2021

TGF-beta signal transduction

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Cancer-associated transforming growth factor beta type II receptor gene mutant causes activation of bone morphogenic protein-Smads and invasive phenotype

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Transforming growth factor beta-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

How the Smads regulate transcription

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Attenuation of the TGF-beta-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-beta-induced growth arrest.

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Crystal Structure of a Phosphorylated Smad2

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Ubiquitin-dependent degradation of TGF-beta-activated smad2.

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

CRM1 is an export receptor for leucine-rich nuclear export signals

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Using viral species specificity to define a critical protein/RNA interaction surface

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Kinesin-mediated transport of Smad2 is required for signaling in response to TGF-beta ligands.

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Analysis of Smad nucleocytoplasmic shuttling in living cells

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Nuclear targeting of transforming growth factor-beta-activated Smad complexes

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Identification of phosphatases for Smad in the BMP/DPP pathway

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling.

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Pushing the envelope: structure, function, and dynamics of the nuclear periphery

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Transport between the cell nucleus and the cytoplasm

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Nucleocytoplasmic shuttling of signal transducers.

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Importin beta mediates nuclear translocation of Smad 3

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Transforming growth factor-beta induces nuclear import of Smad3 in an importin-beta1 and Ran-dependent manner

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

In or out? The dynamics of Smad nucleocytoplasmic shuttling

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Nucleocytoplasmic shuttling of Smad1 conferred by its nuclear localization and nuclear export signals

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

An extended bipartite nuclear localization signal in Smad4 is required for its nuclear import and transcriptional activity

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Distinct domain utilization by Smad3 and Smad4 for nucleoporin interaction and nuclear import.

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Msk is required for nuclear import of TGF-{beta}/BMP-activated Smads

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Identification of two Smad4 proteins in Xenopus. Their common and distinct properties

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

A novel nuclear export signal in Smad1 is essential for its signaling activity

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

The mechanism of nuclear export of Smad3 involves exportin 4 and Ran

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

The nuclear import function of Smad2 is masked by SARA and unmasked by TGFbeta-dependent phosphorylation.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Nucleocytoplasmic shuttling of STAT transcription factors.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Getting the message across, STAT! Design principles of a molecular signaling circuit.

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https://api.crossref.org/works/10.1038%2FCR.2008.325

7 January 2021

Identifiers

DOI

10.1038/CR.2008.325

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Dimensions Publication ID

19 August 2017

1046758489

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