Distinct roles for fibroblast growth factor signaling in cerebellar development and medulloblastoma. (Q37256791)

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10 March 2020

title

Distinct roles for fibroblast growth factor signaling in cerebellar development and medulloblastoma (English)

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10 March 2020

B A Emmenegger

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10 March 2020

E I Hwang

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10 March 2020

C Moore

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10 March 2020

S L Markant

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10 March 2020

S N Brun

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10 March 2020

J W Dutton

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10 March 2020

M P Fogarty

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10 March 2020

A R Singh

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10 March 2020

D L Durden

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10 March 2020

C Yang

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10 March 2020

W L McKeehan

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10 March 2020

R J Wechsler-Reya

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10 March 2020

language of work or name

English

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publication date

8 October 2012

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10 March 2020

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volume

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issue

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10 March 2020

page(s)

4181-4188

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Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

10 March 2020

cites work

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Medulloblastoma comprises four distinct molecular variants

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The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

6 September 2017

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Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

6 September 2017

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Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells

6 September 2017

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Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma

6 September 2017

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6 September 2017

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Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development

6 September 2017

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Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells.

6 September 2017

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

6 September 2017

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Decoding the Hedgehog signal in animal development.

6 September 2017

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The level of sonic hedgehog signaling regulates the complexity of cerebellar foliation

6 September 2017

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Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling.

6 September 2017

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Isolation of neural stem cells from the postnatal cerebellum

6 September 2017

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Cellular signaling by fibroblast growth factor receptors

6 September 2017

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Identification of human brain tumour initiating cells

6 September 2017

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Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum

6 September 2017

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Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors

6 September 2017

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Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth

6 September 2017

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Pituitary adenylate cyclase-activating polypeptide and sonic hedgehog interact to control cerebellar granule precursor cell proliferation

6 September 2017

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Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex

6 September 2017

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Genetic regulation of cerebellar development

6 September 2017

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Sonic hedgehog regulates the growth and patterning of the cerebellum

6 September 2017

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Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

6 September 2017

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Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

6 September 2017

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6 September 2017

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FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung

6 September 2017

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Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development

6 September 2017

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6 September 2017

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Effects of basic fibroblast growth factor on the differentiation, growth, and viability of a new human medulloblastoma cell line (UM-MB1).

6 September 2017

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Altered neural cell fates and medulloblastoma in mouse patched mutants

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations

14 September 2017

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The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas

14 September 2017

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Effects of basic fibroblastic growth factor on the growth of human medulloblastoma xenografts

14 September 2017

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Math1-driven GFP expression in the developing nervous system of transgenic mice

14 September 2017

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Identification of an N-cadherin motif that can interact with the fibroblast growth factor receptor and is required for axonal growth.

14 September 2017

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Semirational design of a potent, artificial agonist of fibroblast growth factor receptors

28 September 2017

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Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

28 September 2017

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Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma

26 June 2018

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Phorbol esters inhibit the Hedgehog signalling pathway downstream of Suppressor of Fused, but upstream of Gli.

26 June 2018

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Basic fibroblast growth factor and fibroblast growth factor receptors in adult olfactory epithelium

26 June 2018

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Fibroblast growth factor receptor 4, implicated in progression of islet cell carcinogenesis by its expression profile, does not contribute functionally.

26 June 2018

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Cerebellar mutant mice and chimeras revisited

26 June 2018

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Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells

26 June 2018

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The cellular kinetics of the developing mouse cerebellum. I. The generation cycle, growth fraction and rate of proliferation of the external granular layer

26 June 2018

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The effects of early hypo- and hyperthyroidism on the development of rat cerebellar cortex. I. Cell proliferation and differentiation

26 June 2018

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Agonists of fibroblast growth factor receptor induce neurite outgrowth and survival of cerebellar granule neurons.

26 June 2018

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Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development

3 September 2018

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3 September 2018

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3 September 2018

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Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma.

3 September 2018

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3 September 2018

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Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling.

3 September 2018

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Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors.

3 September 2018

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3 September 2018

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Vitronectin regulates Sonic hedgehog activity during cerebellum development through CREB phosphorylation.

3 September 2018

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Discrete localizations of hedgehog signalling components in the developing and adult rat nervous system.

3 September 2018

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meander tail acts intrinsic to granule cell precursors to disrupt cerebellar development: analysis of meander tail chimeric mice.

3 September 2018

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H3-thymidine autoradiographic studies on the cell proliferation and differentiation in the external and the internal granular layers of the mouse cerebellum.

3 September 2018

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3 September 2018

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fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation

21 January 2018

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Generation of Fgfr1 conditional knockout mice

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23045271

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2012.440

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23045271%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23045271%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

23045271

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23045271%20AND%20SRC:MED&resulttype=core&format=json