Transgenic mouse with the herpes simplex virus type 1 latency-associated gene: expression and function of the transgene (Q37059659)

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20 December 2019

title

Transgenic mouse with the herpes simplex virus type 1 latency-associated gene: expression and function of the transgene (English)

1 reference

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Herpes simplex virus type 1

20 December 2019

main subject

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20 December 2019

Nurith Mador

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20 December 2019

Efrat Braun

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20 December 2019

Ilana Ariel

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20 December 2019

Amos Panet

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20 December 2019

Israel Steiner

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20 December 2019

language of work or name

English

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publication date

1 December 2003

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20 December 2019

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20 December 2019

volume

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20 December 2019

issue

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20 December 2019

page(s)

12421-12429

1 reference

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The latency-associated gene of herpes simplex virus type 1 (HSV-1) interferes with superinfection by HSV-1.

20 December 2019

cites work

1 reference

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Quantitative stability of DNA after extended storage of clinical specimens as determined by real-time PCR.

29 September 2017

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A protein encoded by the herpes simplex virus (HSV) type 1 2-kilobase latency-associated transcript is phosphorylated, localized to the nucleus, and overcomes the repression of expression from exogenous promoters when inserted into the quiescent HSV

29 September 2017

1 reference

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Regions of the herpes simplex virus type 1 latency-associated transcript that protect cells from apoptosis in vitro and protect neuronal cells in vivo

29 September 2017

1 reference

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The 2-kilobase intron of the herpes simplex virus type 1 latency-associated transcript has a half-life of approximately 24 hours in SY5Y and COS-1 cells

29 September 2017

1 reference

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Herpes simplex virus type 1 2-kilobase latency-associated transcript intron associates with ribosomal proteins and splicing factors

29 September 2017

1 reference

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The 2.2-kilobase latency-associated transcript of herpes simplex virus type 2 does not modulate viral replication, reactivation, or establishment of latency in transgenic mice

29 September 2017

1 reference

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Alternative RNA splicing in the nervous system

29 September 2017

1 reference

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Herpes simplex virus type 1 latency-associated transcript gene promotes neuronal survival

29 September 2017

1 reference

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Region of herpes simplex virus type 1 latency-associated transcript sufficient for wild-type spontaneous reactivation promotes cell survival in tissue culture

29 September 2017

1 reference

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Herpes simplex virus type 1 glycoprotein E domains involved in virus spread and disease

29 September 2017

1 reference

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Molecular circuitry regulating herpes simplex virus type 1 latency in neurons.

29 September 2017

1 reference

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Virus-induced neuronal apoptosis blocked by the herpes simplex virus latency-associated transcript.

29 September 2017

1 reference

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The latent herpes simplex virus type 1 genome copy number in individual neurons is virus strain specific and correlates with reactivation

29 September 2017

1 reference

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Herpes simplex virus type 1 latency-associated transcripts suppress viral replication and reduce immediate-early gene mRNA levels in a neuronal cell line

29 September 2017

1 reference

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Atypical splicing of the latency-associated transcripts of herpes simplex type 1.

29 September 2017

1 reference

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Ah receptor regulation of CYP1B1 expression in primary mouse embryo-derived cells

29 September 2017

1 reference

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A viral function represses accumulation of transcripts from productive-cycle genes in mouse ganglia latently infected with herpes simplex virus

29 September 2017

1 reference

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The herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latency

29 September 2017

1 reference

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The abundant latency-associated transcripts of herpes simplex virus type 1 are bound to polyribosomes in cultured neuronal cells and during latent infection in mouse trigeminal ganglia

29 September 2017

1 reference

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A 348-base-pair region in the latency-associated transcript facilitates herpes simplex virus type 1 reactivation.

29 September 2017

1 reference

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The enhancer domain of the human cytomegalovirus major immediate-early promoter determines cell type-specific expression in transgenic mice

29 September 2017

1 reference

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Herpes simplex virus type 1 DNA replication and gene expression during explant-induced reactivation of latently infected murine sensory ganglia

29 September 2017

1 reference

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Two open reading frames (ORF1 and ORF2) within the 2.0-kilobase latency-associated transcript of herpes simplex virus type 1 are not essential for reactivation from latency

29 September 2017

1 reference

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Expression and splicing of the latency-associated transcripts of herpes simplex virus type 1 in neuronal and non-neuronal cell lines

29 September 2017

1 reference

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Herpes simplex type 1 DNA in human brain tissue

29 September 2017

1 reference

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Latent herpes simplex virus type 1 transcription in human trigeminal ganglia

29 September 2017

1 reference

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Detection of herpes simplex virus type 1 transcripts during latent infection in mice

29 September 2017

1 reference

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A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency

29 September 2017

1 reference

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Herpes simplex virus type 1 latency-associated transcripts are evidently not essential for latent infection

29 September 2017

1 reference

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Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript.

29 September 2017

1 reference

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Regulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1.

29 September 2017

1 reference

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A herpes simplex virus type 1 mutant containing a nontransinducing Vmw65 protein establishes latent infection in vivo in the absence of viral replication and reactivates efficiently from explanted trigeminal ganglia

29 September 2017

1 reference

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The variability in activity of the universally expressed human cytomegalovirus immediate early gene 1 enhancer/promoter in transgenic mice

29 September 2017

1 reference

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In vivo and in vitro reactivation impairment of a herpes simplex virus type 1 latency-associated transcript variant in a rabbit eye model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262558

Identification of a novel latency-specific splice donor signal within the herpes simplex virus type 1 2.0-kilobase latency-associated transcript (LAT): translation inhibition of LAT open reading frames by the intron within the 2.0-kilobase LAT

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262558

Herpes simplex virus latent infection in the nervous system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262558

The DNA sequences of the long repeat region and adjoining parts of the long unique region in the genome of herpes simplex virus type 1.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262558

A herpes simplex virus transcript abundant in latently infected neurons is dispensable for establishment of the latent state

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262558

Mapping of low abundance latency-associated RNA in the trigeminal ganglia of mice latently infected with herpes simplex virus type 1.

27 June 2018

1 reference

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Herpes simplex virus latent phase transcription facilitates in vivo reactivation

27 June 2018

1 reference

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A quantitative microwell assay for chondrocyte cell adhesion.

27 June 2018

1 reference

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Tissue specific distribution of the herpes simplex virus type 1 latency-associated transcripts on polyribosomes during latent infection.

27 June 2018

1 reference

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Herpes simplex virus type 1 gene expression and reactivation of latent infection in the central nervous system

4 September 2018

1 reference

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Analysis by RNA-PCR of latency and reactivation of herpes simplex virus in multiple neuronal tissues

4 September 2018

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Mouse actin messenger RNAs. Construction and characterization of a recombinant plasmid molecule containing a complementary DNA transcript of mouse alpha-actin mRNA

4 September 2018

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The HSV-1 2-kb latency-associated transcript is found in the cytoplasm comigrating with ribosomal subunits during productive infection

4 September 2018

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12 December 2020

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

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12 December 2020

Predominant transgene expression in exocrine pancreas directed by the CMV promoter

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12 December 2020

RNA complementary to a herpesvirus alpha gene mRNA is prominent in latently infected neurons

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12 December 2020

10.1128/JVI.77.23.12421-12429.2003

Identifiers

DOI

1 reference

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20 December 2019

1 reference

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20 December 2019

PubMed publication ID

14610166

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14610166%20AND%20SRC:MED&resulttype=core&format=json