Potent and nontoxic antisense oligonucleotides containing locked nucleic acids (Q36985622)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10805816%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Potent and nontoxic antisense oligonucleotides containing locked nucleic acids (English)

1 reference

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6 November 2019

1 reference

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6 November 2019

T Hökfelt

1 reference

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6 November 2019

C Wahlestedt

1 reference

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6 November 2019

P Salmi

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6 November 2019

L Good

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6 November 2019

J Kela

1 reference

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6 November 2019

T Johnsson

1 reference

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6 November 2019

C Broberger

1 reference

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6 November 2019

F Porreca

1 reference

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6 November 2019

J Lai

1 reference

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6 November 2019

K Ren

1 reference

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6 November 2019

M Ossipov

1 reference

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6 November 2019

A Koshkin

1 reference

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6 November 2019

N Jakobsen

1 reference

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6 November 2019

J Skouv

1 reference

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6 November 2019

H Oerum

1 reference

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6 November 2019

M H Jacobsen

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6 November 2019

language of work or name

English

0 references

publication date

1 May 2000

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

6 November 2019

published in

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6 November 2019

volume

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6 November 2019

issue

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6 November 2019

page(s)

5633-5638

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Structural studies of LNA:RNA duplexes by NMR: conformations and implications for RNase H activity

6 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Brain as a unique antisense environment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Applications of peptide nucleic acids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Modification of phosphorothioate oligonucleotides yields potent analogs with minimal toxicity for antisense experiments in the CNS.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Peptide nucleic acids (PNA) and PNA-DNA chimeras: from high binding affinity towards biological function.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Characterization of antinociception to opioid receptor selective agonists after antisense oligodeoxynucleotide-mediated "knock-down" of opioid receptor in vivo.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Antisense oligonucleotide strategies in neuropharmacology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Selective loss of delta opioid analgesia and binding by antisense oligodeoxynucleotides to a delta opioid receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Studies on the direct spinal action of narcotics in the production of analgesia in the rat

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Keeping the biotechnology of antisense in context.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

A good antisense molecule is hard to find

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

An antisense oligodeoxynucleotide to the delta opioid receptor (DOR-1) inhibits morphine tolerance and acute dependence in mice

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Nucleosides with a twist. Can fixed forms of sugar ring pucker influence biological activity in nucleosides and oligonucleotides?

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Antagonism by SCH 23390 of clozapine-induced hypothermia in the rat.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Use of antisense vectors and oligodeoxynucleotides in neuro-oncology

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

A biosynthetic approach for the incorporation of unnatural amino acids into proteins

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Characterization of supraspinal antinociceptive actions of opioid delta agonists in the rat.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

Antisense oligodeoxynucleotide to a delta-opioid receptor selectively blocks the spinal antinociception induced by delta-, but not mu- or kappa-opioid receptor agonists in the mouse

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=25880

A Novel Class of Oligonucleotide Analogues Containing 2‘-O,3‘-C-Linked [3.2.0]Bicycloarabinonucleoside Monomers: Synthesis, Thermal Affinity Studies, and Molecular Modeling

4 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.10.5633

LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.10.5633

LNA (Locked Nucleic Acid): An RNA Mimic Forming Exceedingly Stable LNA:LNA Duplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.10.5633

Synthesis of 3‘-C- and 4‘-C-Branched Oligodeoxynucleotides and the Development of Locked Nucleic Acid (LNA)

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.10.5633

Purification and characterization of tyrosine hydroxylase from a clonal pheochromocytoma cell line

21 January 2018

1 reference

12 December 2020

Mixed-backbone oligonucleotides as second-generation antisense agents with reduced phosphorothioate-related side effects

1 reference

12 December 2020

Antisense therapeutics

1 reference

12 December 2020

Antisense oligonucleotides - the way forward

1 reference

12 December 2020

Vitravene--another piece in the mosaic

1 reference

12 December 2020

Differential effects of intrastriatally infused fully and endcap phosphorothioate antisense oligonucleotides on morphology, histochemistry and prodynorphin expression in rat brain

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.97.10.5633

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10805816%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10805816%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

10805816

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10805816%20AND%20SRC:MED&resulttype=core&format=json