Identification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase. (Q36701792)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18387945%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Identification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase (English)

1 reference

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5 January 2020

0 references

1 reference

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5 January 2020

Wei Bin Fang

1 reference

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5 January 2020

Dana M Brantley-Sieders

series ordinal

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5 January 2020

Yoonha Hwang

series ordinal

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5 January 2020

Amy-Joan L Ham

series ordinal

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5 January 2020

language of work or name

English

0 references

publication date

3 April 2008

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Journal of Biological Chemistry

5 January 2020

published in

1 reference

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5 January 2020

volume

283

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5 January 2020

issue

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5 January 2020

page(s)

16017-16026

1 reference

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An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

5 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism.

30 September 2017

1 reference

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Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis

30 September 2017

1 reference

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EphB4 controls blood vascular morphogenesis during postnatal angiogenesis

30 September 2017

1 reference

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Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Eph receptor signalling casts a wide net on cell behaviour

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

P-Mod: an algorithm and software to map modifications to peptide sequences using tandem MS data

30 September 2017

1 reference

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Eph receptor tyrosine kinases in tumor and tumor microenvironment

30 September 2017

1 reference

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Eph receptor tyrosine kinases in angiogenesis: from development to disease.

30 September 2017

1 reference

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Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

EphA kinase activation regulates HGF-induced epithelial branching morphogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Activation of the EphA2 tyrosine kinase stimulates the MAP/ERK kinase signaling cascade

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Regulation of the EphA2 kinase by the low molecular weight tyrosine phosphatase induces transformation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Negative regulation of EphA2 receptor by Cbl.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Vascular patterning by Eph receptor tyrosine kinases and ephrins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Rho GTPases and cell migration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

In vivo tyrosine phosphorylation sites of activated ephrin-B1 and ephB2 from neural tissue

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Engineering and characterization of functional human microvessels in immunodeficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Phosphorylation of tyrosine residues in the kinase domain and juxtamembrane region regulates the biological and catalytic activities of Eph receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Multiple in vivo tyrosine phosphorylation sites in EphB receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Activation of the Eck receptor protein tyrosine kinase stimulates phosphatidylinositol 3-kinase activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Method to correlate tandem mass spectra of modified peptides to amino acid sequences in the protein database

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Characterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

LMW-PTP is a negative regulator of insulin-mediated mitotic and metabolic signalling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

c-Cbl-dependent EphA2 protein degradation is induced by ligand binding.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Cardiovascular ephrinB2 function is essential for embryonic angiogenesis.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2414276

Ephrin-A1 facilitates mammary tumor metastasis through an angiogenesis-dependent mechanism mediated by EphA receptor and vascular endothelial growth factor in mice

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18387945

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M709934200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18387945%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18387945%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

PubMed publication ID

18387945

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18387945%20AND%20SRC:MED&resulttype=core&format=json