An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice. (Q36596732)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9380721%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice (English)

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7 November 2019

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7 November 2019

N Noben-Trauth

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7 November 2019

L D Shultz

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7 November 2019

F Brombacher

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7 November 2019

H Gu

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7 November 2019

W E Paul

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7 November 2019

language of work or name

English

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publication date

1 September 1997

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Proceedings of the National Academy of Sciences of the United States of America

7 November 2019

published in

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7 November 2019

volume

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7 November 2019

issue

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7 November 2019

page(s)

10838-10843

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Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells

7 November 2019

cites work

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Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse

9 September 2017

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Beta 2-microglobulin-dependent T cells are dispensable for allergen-induced T helper 2 responses

9 September 2017

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Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses

9 September 2017

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Selective development of T helper (Th)2 cells induced by continuous administration of low dose soluble proteins to normal and beta(2)-microglobulin-deficient BALB/c mice

9 September 2017

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Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

9 September 2017

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Essential role of Stat6 in IL-4 signalling

9 September 2017

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Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

9 September 2017

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Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor

9 September 2017

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Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor

9 September 2017

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Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4

9 September 2017

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Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes

9 September 2017

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Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15

9 September 2017

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Acquisition of lymphokine-producing phenotype by CD4+ T cells

9 September 2017

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Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex

9 September 2017

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Increased expression of Ia antigens on resting B cells: an additional role for B-cell growth factor

9 September 2017

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Up-regulation of interleukin 4/B-cell stimulatory factor 1 receptor expression

9 September 2017

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Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

9 September 2017

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Interleukin-4: a prototypic immunoregulatory lymphokine

9 September 2017

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Simplified mammalian DNA isolation procedure

9 September 2017

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Cloning of the gamma chain of the human IL-2 receptor

9 September 2017

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The murine interleukin-4 receptor gene: genomic structure, expression and potential for alternative splicing

9 September 2017

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Efficient targeting of the IL-4 gene in a BALB/c embryonic stem cell line

9 September 2017

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CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3.

30 September 2017

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Mouse CD1-specific NK1 T cells: development, specificity, and function

30 September 2017

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Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

28 June 2018

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B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells.

28 June 2018

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Effect of B cell stimulatory factor-1 (interleukin 4) on Fc epsilon and Fc gamma receptor expression on murine B lymphocytes and B cell lines

28 June 2018

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Derivation of a T cell line that is highly responsive to IL-4 and IL-2 (CT.4R) and of an IL-2 hyporesponsive mutant of that line (CT.4S).

28 June 2018

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28 June 2018

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Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1.

28 June 2018

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Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.

28 June 2018

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Production of interleukin-4 and other cytokines following stimulation of mast cell lines and in vivo mast cells/basophils.

28 June 2018

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Monoclonal antibodies block murine IL-4 receptor function

28 June 2018

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Generation of B cell memory and affinity maturation. Induction with Th1 and Th2 T cell clones

28 June 2018

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Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

28 June 2018

1 reference

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A minority subpopulation of CD4+ T cells directs the development of naive CD4+ T cells into IL-4-secreting cells.

20 September 2018

1 reference

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Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores

20 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.94.20.10838

Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.94.20.10838

Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor

21 January 2018

1 reference

12 December 2020

Early production of IL-4 and induction of Th2 responses in the lymph node originate from an MHC class I-independent CD4+NK1.1- T cell population

1 reference

12 December 2020

A sensitive immunochemical assay for biologically active MuIFN-gamma

1 reference

12 December 2020

A novel large granular lymphocyte-like cell isolated from IL-2-supplemented murine intestinal lamina propria lymphocyte cultures with potent inhibitory action on lymphocyte proliferation

1 reference

12 December 2020

Quick nested PCR screening of ES cell clones for gene targeting events

1 reference

12 December 2020

Interleukin 4 receptor: signaling mechanisms

1 reference

12 December 2020

In susceptible mice, Leishmania major induce very rapid interleukin-4 production by CD4+ T cells which are NK1.1-

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.94.20.10838

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9380721%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9380721%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

PubMed publication ID

9380721

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9380721%20AND%20SRC:MED&resulttype=core&format=json