Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells. (Q36403529)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186187%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells (English)

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7 January 2020

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7 January 2020

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7 January 2020

Shimon Sakaguchi

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7 January 2020

Tsutomu Chiba

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7 January 2020

Kuibeom Ko

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7 January 2020

Sayuri Yamazaki

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7 January 2020

Kyoko Nakamura

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7 January 2020

Tomohisa Nishioka

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7 January 2020

Jun Shimizu

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7 January 2020

Takashi Nomura

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7 January 2020

language of work or name

English

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publication date

26 September 2005

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Journal of Experimental Medicine

7 January 2020

published in

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7 January 2020

volume

202

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7 January 2020

issue

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7 January 2020

page(s)

885-891

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Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors

7 January 2020

cites work

1 reference

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Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

30 September 2017

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Cancer immunotherapy: moving beyond current vaccines

30 September 2017

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GITR activation induces an opposite effect on alloreactive CD4(+) and CD8(+) T cells in graft-versus-host disease

30 September 2017

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Costimulation via glucocorticoid-induced TNF receptor in both conventional and CD25+ regulatory CD4+ T cells

30 September 2017

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Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression

30 September 2017

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Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

30 September 2017

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GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations

30 September 2017

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CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination.

30 September 2017

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Regulatory cells in transplantation.

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Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

30 September 2017

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

30 September 2017

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

30 September 2017

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Control of regulatory T cell development by the transcription factor Foxp3

30 September 2017

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Tumor-specific shared antigenic peptides recognized by human T cells

30 September 2017

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The roles of IFN gamma in protection against tumor development and cancer immunoediting

30 September 2017

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CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

30 September 2017

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Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

30 September 2017

1 reference

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Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

30 September 2017

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CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy

30 September 2017

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Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

30 September 2017

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Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

30 September 2017

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B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

30 September 2017

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Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity

30 September 2017

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30 September 2017

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30 September 2017

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Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells.

28 June 2018

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Distinct roles of CTLA-4 and TGF-beta in CD4+CD25+ regulatory T cell function

21 September 2018

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Autoreactive T cells in healthy individuals

21 September 2018

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Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infection

21 September 2018

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21 September 2018

Identifiers

DOI

10.1084/JEM.20050940

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16186187%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

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7 January 2020

PubMed publication ID

16186187

1 reference

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