Restrictions limiting the generation of DNA double strand breaks during chromosomal V(D)J recombination (Q36369844)

13 August 2017

Restrictions limiting the generation of DNA double strand breaks during chromosomal V(D)J recombination (English)

1 reference

13 August 2017

Robert E Tillman

1 reference

13 August 2017

Andrea L Wooley

1 reference

13 August 2017

Maureen M Hughes

1 reference

13 August 2017

Tara D Wehrly

1 reference

13 August 2017

Wojciech Swat

1 reference

13 August 2017

Barry P Sleckman

1 reference

13 August 2017

language of work or name

English

0 references

publication date

1 February 2002

1 reference

Journal of Experimental Medicine

13 August 2017

1 reference

13 August 2017

195

1 reference

13 August 2017

1 reference

13 August 2017

309-316

1 reference

Factors and forces controlling V(D)J recombination

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Mechanisms that direct ordered assembly of T cell receptor beta locus V, D, and J gene segments

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Intermolecular V(D)J recombination is prohibited specifically at the joining step

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Identification of genes involved in repair of DNA double-strand breaks in mammalian cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Enhancer control of local accessibility to V(D)J recombinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Ku86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Initiation of V(D)J recombination in vitro obeying the 12/23 rule

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Initiation of V(D)J recombination in a cell-free system.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

V(D)J recombination and double-strand break repair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Somatic generation of antibody diversity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Ordered rearrangement of immunoglobulin heavy chain variable region segments

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Cutting and closing without recombination in V(D)J joining

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

V(D)J recombination: molecular biology and regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Interallelic V(D)J trans-rearrangement within the beta T cell receptor gene is infrequent and occurs preferentially during attempted D beta to J beta joining

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Recent advances in understanding V(D)J recombination.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

Rejoining of DNA by the RAG1 and RAG2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

Novel strand exchanges in V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

Function of the TCR alpha enhancer in alphabeta and gammadelta T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

V(D)J Recombination in Ku86-Deficient Mice: Distinct Effects on Coding, Signal, and Hybrid Joint Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

Intermolecular V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

21 January 2018

Identifiers

DOI

10.1084/JEM.20011803

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

11828005

1 reference