Absence of BLM leads to accumulation of chromosomal DNA breaks during both unperturbed and disrupted S phases (Q36322513)

13 August 2017

Absence of BLM leads to accumulation of chromosomal DNA breaks during both unperturbed and disrupted S phases (English)

1 reference

13 August 2017

William G Dunphy

1 reference

13 August 2017

Wenhui Li

1 reference

13 August 2017

Soo-Mi Kim

series ordinal

1 reference

13 August 2017

Joon Lee

series ordinal

1 reference

13 August 2017

language of work or name

English

0 references

publication date

14 June 2004

1 reference

13 August 2017

1 reference

inferred from page(s)

published in

Journal of Cell Biology

1 reference

13 August 2017

165

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13 August 2017

1 reference

13 August 2017

801-812

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describes a project that uses

13 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2172405/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Stimulation of flap endonuclease-1 by the Bloom's syndrome protein

30 September 2017

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XRad17 is required for the activation of XChk1 but not XCds1 during checkpoint signaling in Xenopus

30 September 2017

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DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1.

30 September 2017

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The human Bloom syndrome gene suppresses the DNA replication and repair defects of yeast dna2 mutants

30 September 2017

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30 September 2017

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Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17.

30 September 2017

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Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1

30 September 2017

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ATR Regulates Fragile Site Stability

30 September 2017

1 reference

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Checking on the fork: the DNA-replication stress-response pathway

30 September 2017

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The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha

30 September 2017

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A requirement for replication in activation of the ATR-dependent DNA damage checkpoint

30 September 2017

1 reference

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DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts

30 September 2017

1 reference

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Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM

30 September 2017

1 reference

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Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae

30 September 2017

1 reference

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Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest

30 September 2017

1 reference

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A unified view of the DNA-damage checkpoint

30 September 2017

1 reference

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CHK2 kinase--a busy messenger.

30 September 2017

1 reference

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Cell cycle checkpoint signaling through the ATM and ATR kinases

30 September 2017

1 reference

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Evidence for BLM and Topoisomerase IIIalpha interaction in genomic stability

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172405

Bloom helicase is involved in DNA surveillance in early S phase in vertebrate cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172405

Functions of RecQ family helicases: possible involvement of Bloom's and Werner's syndrome gene products in guarding genome integrity during DNA replication

30 September 2017

1 reference

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ATM-dependent phosphorylation and accumulation of endogenous BLM protein in response to ionizing radiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172405

Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

30 September 2017

1 reference

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Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172405

The function of Xenopus Bloom's syndrome protein homolog (xBLM) in DNA replication

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172405

Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase alpha

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172405

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

30 September 2017

1 reference

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The G2-phase DNA-damage checkpoint

30 September 2017

1 reference

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Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends

30 September 2017

1 reference

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BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172405

The Bloom's syndrome gene product interacts with topoisomerase III

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172405

Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172405

The yeast Sgs1p helicase acts upstream of Rad53p in the DNA replication checkpoint and colocalizes with Rad53p in S-phase-specific foci

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172405

The Xenopus Chk1 protein kinase mediates a caffeine-sensitive pathway of checkpoint control in cell-free extracts

30 September 2017

1 reference

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Geminin, an inhibitor of DNA replication, is degraded during mitosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172405

Drosophila BLM in double-strand break repair by synthesis-dependent strand annealing

30 September 2017

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200402095

Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200402095

Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200402095

Constitutive DNA damage is linked to DNA replication abnormalities in Bloom's syndrome cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200402095

Xenopus Drf1, a regulator of Cdc7, displays checkpoint-dependent accumulation on chromatin during an S-phase arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200402095

The role of single-stranded DNA and polymerase alpha in establishing the ATR, Hus1 DNA replication checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200402095

Focus-formation of replication protein A, activation of checkpoint system and DNA repair synthesis induced by DNA double-strand breaks in Xenopus egg extract.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172405

Genetic analysis of the Saccharomyces cerevisiae Sgs1 helicase defines an essential function for the Sgs1-Top3 complex in the absence of SRS2 or TOP1

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15197177

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.200402095

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

15197177

1 reference