Serotonin neurotoxins--past and present (Q36003842)

https://api.crossref.org/works/10.1007%2FBF03033455

Serotonin neurotoxicity after (+/-)3,4-methylenedioxymethamphetamine (MDMA; "Ecstasy"): a controlled study in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033455

Neurotoxicity of MDMA and related compounds: anatomic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033455

N-tert-butyl-alpha-phenylnitrone protects against 3,4-methylenedioxymethamphetamine-induced depletion of serotonin in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033455

The N-methyl-D-aspartate antagonist MK-801 protects against serotonin depletions induced by methamphetamine, 3,4-methylenedioxymethamphetamine and p-chloroamphetamine

21 January 2018

1 reference

12 December 2020

5,7-Dihydroxytryptamine: improvement of its selectivity for serotonin neurons in the CNS by pretreatment with desipramine

1 reference

12 December 2020

Oxidation of vitamin E, vitamin C, and thiols in rat brain synaptosomes by peroxynitrite

1 reference

12 December 2020

Immunohistochemical analysis of the neurotoxic effects of DSP-4 identifies two populations of noradrenergic axon terminals

1 reference

12 December 2020

Methylenedioxymethamphetamine: a potentially neurotoxic amphetamine analogue

1 reference

12 December 2020

Methamphetamine-induced neurotoxicity is attenuated in transgenic mice with a null mutation for interleukin-6.

1 reference

12 December 2020

Neuronal, astroglial and microglial cytokine expression after an excitotoxic lesion in the immature rat brain.

1 reference

12 December 2020

d-MDMA during vitamin E deficiency: effects on dopaminergic neurotoxicity and hepatotoxicity

1 reference

12 December 2020

Oxidation of serotonin by superoxide radical: implications to neurodegenerative brain disorders

1 reference

12 December 2020

Enhancement of 3,4-methylenedioxymethamphetamine neurotoxicity by the energy inhibitor malonate

1 reference

12 December 2020

Cerebral metabolism of some serotonin depletors

1 reference

12 December 2020

Hepatotoxicity of 3,4-methylenedioxyamphetamine and alpha-methyldopamine in isolated rat hepatocytes: formation of glutathione conjugates

1 reference

12 December 2020

Formation of 6-hydroxydopamine in caudate nucleus of the rat brain after a single large dose of methylamphetamine

1 reference

12 December 2020

Serotonergic neurotoxicity of 3,4-(+/-)-methylenedioxyamphetamine and 3,4-(+/-)-methylendioxymethamphetamine (ecstasy) is potentiated by inhibition of gamma-glutamyl transpeptidase

1 reference

12 December 2020

Adverse neuropsychiatric events associated with dexfenfluramine and fenfluramine

1 reference

12 December 2020

Null mutation of c-fos causes exacerbation of methamphetamine-induced neurotoxicity

1 reference

12 December 2020

Serotonin syndrome and other serotonergic disorders

1 reference

12 December 2020

Mechanisms of regrowth in the bulbospinal serotonin system following 5,6-dihydroxytryptamine induced axotomy. II. Fluorescence histochemical observations

1 reference

12 December 2020

Measurement of human brain dexfenfluramine concentration by 19F magnetic resonance spectroscopy

1 reference

12 December 2020

Methamphetamine induces apoptosis in an immortalized rat striatal cell line by activating the mitochondrial cell death pathway

1 reference

12 December 2020

(+/-)3,4-Methylenedioxymethamphetamine ('Ecstasy')-induced serotonin neurotoxicity: studies in animals

1 reference

12 December 2020

Axonal degeneration and regeneration of bulbo-spinal indolamine neurons after 5,6-dihydroxytryptamine treatment

1 reference

12 December 2020

Caveat emptor: editors beware

1 reference

12 December 2020

Synthesis, in vitro formation, and behavioural effects of glutathione regioisomers of alpha-methyldopamine with relevance to MDA and MDMA (ecstasy).

1 reference

12 December 2020

Repeated doses administration of MDMA in humans: pharmacological effects and pharmacokinetics.

1 reference

12 December 2020

The Pharmacology of 6-Hydroxydopamine

1 reference

12 December 2020

Dexfenfluramine and serotonin neurotoxicity: further preclinical evidence that clinical caution is indicated.

1 reference

12 December 2020

The metabolism and toxicity of quinones, quinonimines, quinone methides, and quinone-thioethers

1 reference

12 December 2020

Methamphetamine induces neuronal apoptosis via cross-talks between endoplasmic reticulum and mitochondria-dependent death cascades

1 reference

12 December 2020

Brain concentrations of d-MDMA are increased after stress

1 reference

12 December 2020

Non-linear pharmacokinetics of MDMA ('ecstasy') in humans

1 reference

12 December 2020

Toxicodynamics and long-term toxicity of the recreational drug, 3, 4-methylenedioxymethamphetamine (MDMA, 'Ecstasy').

1 reference

12 December 2020

Neurotoxic indoleamines and monoamine neurons

1 reference

12 December 2020

2,5-Bis-(glutathion-S-yl)-alpha-methyldopamine, a putative metabolite of (+/-)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations

1 reference

12 December 2020

Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.

1 reference

12 December 2020

Elevated environmental temperature and methamphetamine neurotoxicity

1 reference

12 December 2020

Selective blockade of mGlu5 metabotropic glutamate receptors is protective against methamphetamine neurotoxicity.

1 reference

12 December 2020

Oral kinetics of dexfenfluramine and dexnorfenfluramine in non-human primates

1 reference

12 December 2020

Evaluation of the effects of 5,7-dihydroxytryptamine on serotonin and catecholamine neurons in the rat CNS.

1 reference

12 December 2020

3,4-Dihydroxymethamphetamine (HHMA). A major in vivo 3,4-methylenedioxymethamphetamine (MDMA) metabolite in humans

1 reference

12 December 2020

Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine

1 reference

12 December 2020

Proteins released from degenerating neurons are surrogate markers for acute brain damage

1 reference

12 December 2020

Methamphetamine- and 1-methyl-4-phenyl- 1,2,3, 6-tetrahydropyridine-induced dopaminergic neurotoxicity in inducible nitric oxide synthase-deficient mice

1 reference

12 December 2020

Fenfluramine-induced serotonergic neurotoxicity in mice: lack of neuroprotection by inhibition/ablation of nNOS.

1 reference

12 December 2020

Altered gene expression in frontal cortex and midbrain of 3,4-methylenedioxymethamphetamine (MDMA) treated mice: differential regulation of GABA transporter subtypes

1 reference

12 December 2020

The molecular mechanism of "ecstasy" [3,4-methylenedioxy-methamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release

1 reference

12 December 2020

Studies on the role of dopamine in the degeneration of 5-HT nerve endings in the brain of Dark Agouti rats following 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy') administration

1 reference

12 December 2020

Temporal profiling of methamphetamine-induced changes in gene expression in the mouse brain: evidence from cDNA array

1 reference

12 December 2020

MDMA-induced neurotoxicity: parameters of degeneration and recovery of brain serotonin neurons

1 reference

12 December 2020

Species differences in the kinetics and metabolism of fenfluramine isomers

1 reference

12 December 2020

UCP3 and thyroid hormone involvement in methamphetamine-induced hyperthermia

1 reference

12 December 2020

A review of the mechanisms involved in the acute MDMA (ecstasy)-induced hyperthermic response

1 reference

12 December 2020

Dihydroxytryptamines as tools to study the neurobiology of serotonin

1 reference

12 December 2020

Attenuation of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy)-induced rhabdomyolysis with alpha1- plus beta3-adrenoreceptor antagonists.

1 reference

12 December 2020

A single dose model of methamphetamine-induced neurotoxicity in rats: effects on neostriatal monoamines and glial fibrillary acidic protein

1 reference

12 December 2020

Effects of amphetamines on mitochondrial function: role of free radicals and oxidative stress

1 reference

12 December 2020

The pharmacokinetics of dexfenfluramine in obese and non-obese subjects

1 reference

12 December 2020

Hydroxyl radical-mediated oxidation of serotonin: potential insights into the neurotoxicity of methamphetamine

1 reference

12 December 2020

High-performance liquid chromatography with electrochemical detection applied to the analysis of 3,4-dihydroxymethamphetamine in human plasma and urine.

1 reference

12 December 2020

Novel anti-inflammatory therapy for Parkinson's disease.

1 reference

12 December 2020

Methamphetamine administration causes overexpression of nNOS in the mouse striatum

1 reference

12 December 2020

Astrocyte-derived nitric oxide causes both reversible and irreversible damage to the neuronal mitochondrial respiratory chain

1 reference

12 December 2020

Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine

1 reference

12 December 2020

Ascorbic acid prevents 3,4-methylenedioxymethamphetamine (MDMA)-induced hydroxyl radical formation and the behavioral and neurochemical consequences of the depletion of brain 5-HT.

1 reference

12 December 2020

Effects of repeated fenfluramine administration on indices of monoamine function in rat brain: pharmacokinetic, dose response, regional specificity and time course data

1 reference

12 December 2020

Nitric oxide and macrophage function

1 reference

12 December 2020

Demonstration and localization of neuronal degeneration in the rat forebrain following a single exposure to MDMA

1 reference

12 December 2020

Inducible nitric oxide synthase-deficient mice have enhanced leukocyte-endothelium interactions in endotoxemia

1 reference

12 December 2020

Methamphetamine neurotoxicity in dopamine nerve endings of the striatum is associated with microglial activation

1 reference

12 December 2020

Analysis of ecstasy (MDMA)-induced transcriptional responses in the rat cortex.

1 reference

12 December 2020

The nNOS inhibitor, AR-R17477AR, prevents the loss of NF68 immunoreactivity induced by methamphetamine in the mouse striatum

1 reference

12 December 2020

Methamphetamine neurotoxicity and striatal glutamate release: comparison to 3,4-methylenedioxymethamphetamine

1 reference

12 December 2020

Polarographic measurements of spontaneous and mitochondria-promoted oxidation of 5,6- and 5,7-dihydroxytryptamine

1 reference

12 December 2020

Microglial activation is a pharmacologically specific marker for the neurotoxic amphetamines

1 reference

12 December 2020

Parvalbumin neuron circuits and microglia in three dopamine-poor cortical regions remain sensitive to amphetamine exposure in the absence of hyperthermia, seizure and stroke

1 reference

12 December 2020

MDMA (Ecstasy) controls in concert a group of genes involved in GABA neurotransmission

1 reference

12 December 2020

Neurotoxicity of MDMA (ecstasy): the limitations of scaling from animals to humans.

1 reference

12 December 2020

3,4-Methylenedioxymethamphetamine increases interleukin-1beta levels and activates microglia in rat brain: studies on the relationship with acute hyperthermia and 5-HT depletion

1 reference

12 December 2020

Disposition of methylenedioxymethamphetamine and three metabolites in the brains of different rat strains and their possible roles in acute serotonin depletion

1 reference

12 December 2020

d-Fenfluramine produces neuronal degeneration in localized regions of the cortex, thalamus, and cerebellum of the rat.

1 reference

12 December 2020

DNA damage and ubiquitinated neuronal inclusions in the substantia nigra and striatum of mice following MDMA (ecstasy).

1 reference

12 December 2020

Resistance of neuronal nitric oxide synthase-deficient mice to methamphetamine-induced dopaminergic neurotoxicity.

1 reference

12 December 2020

Detection of 5-S-cysteinyldopamine in human brain

1 reference

12 December 2020

Identification of differentially regulated transcripts in mouse striatum following methamphetamine treatment--an oligonucleotide microarray approach.

1 reference

12 December 2020

Parallel increases in lipid and protein oxidative markers in several mouse brain regions after methamphetamine treatment

1 reference

12 December 2020

CuZn-superoxide dismutase (CuZnSOD) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (MDA) and of methylenedioxymethamphetamine (MDMA).

1 reference

12 December 2020

Neuropharmacological Effects of Low and High Doses of Repeated Oral Dexfenfluramine in Rats: A Comparison with Fluoxetine

1 reference

12 December 2020

Role of brain nitric oxide in (+/-)3,4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity in rats

1 reference

12 December 2020

Serotonin reuptake inhibitors do not prevent 5,7-dihydroxytryptamine-induced depletion of serotonin in rat brain

1 reference

12 December 2020

5-s-Cysteinyl-conjugates of catecholamines induce cell damage, extensive DNA base modification and increases in caspase-3 activity in neurons

1 reference

12 December 2020

Brain hyperthermia during physiological and pathological conditions: causes, mechanisms, and functional implications

1 reference

12 December 2020

Biological reactivity of polyphenolic-glutathione conjugates

1 reference

12 December 2020

Reorganization of ascending 5-HT axon projections in animals previously exposed to the recreational drug (+/-)3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")

1 reference

12 December 2020

Neurotoxicity profiles of substituted amphetamines in the C57BL/6J mouse

1 reference

12 December 2020

Excitotoxic mitochondrial depolarisation requires both calcium and nitric oxide in rat hippocampal neurons

1 reference

12 December 2020

Neurotoxic effect of MDMA on brain serotonin neurons: evidence from neurochemical and radioligand binding studies

1 reference

12 December 2020

Seizure activity and hyperthermia potentiate the increases in dopamine and serotonin extracellular levels in the amygdala during exposure to d-amphetamine

1 reference

12 December 2020

Relevance of pharmacokinetic parameters in animal models of methamphetamine abuse

1 reference

12 December 2020

MK-801 prevents microglial reaction in rat hippocampus after forebrain ischemia

1 reference

12 December 2020

Methamphetamine produces neuronal inclusions in the nigrostriatal system and in PC12 cells.

1 reference

12 December 2020

Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition

1 reference

12 December 2020

The pharmacology and toxicology of polyphenolic-glutathione conjugates

1 reference

12 December 2020

Degeneration of rat locus coeruleus neurons is not accompanied by an irreversible loss of ascending projections. Evidence for reestablishment of forebrain innervation by surviving neurons

1 reference

12 December 2020

Methamphetamine-induced deficits of brain monoaminergic neuronal markers: distal axotomy or neuronal plasticity

1 reference

12 December 2020

Importance of ERK activation in behavioral and biochemical effects induced by MDMA in mice.

1 reference

12 December 2020

Methamphetamine causes differential regulation of pro-death and anti-death Bcl-2 genes in the mouse neocortex

1 reference

12 December 2020

Neurotoxicity of hydroxylated tryptamines: structure-activity relationships. 2. In vitro studies on monoamine uptake inhibition and uptake impairment

1 reference

12 December 2020

Speed kills: cellular and molecular bases of methamphetamine-induced nerve terminal degeneration and neuronal apoptosis

1 reference

12 December 2020

The role of the sympathetic nervous system and uncoupling proteins in the thermogenesis induced by 3,4-methylenedioxymethamphetamine.

1 reference

12 December 2020

Rapid and transient inhibition of mitochondrial function following methamphetamine or 3,4-methylenedioxymethamphetamine administration

1 reference

12 December 2020

Nitric oxide and calcium together inactivate mitochondrial complex I and induce cytochrome c release

1 reference

12 December 2020

In vitro and in vivo effects of the anorectic agent dexfenfluramine on the central serotoninergic neuronal systems of non-human primates. A comparison with the rat

1 reference

12 December 2020

Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration

1 reference

12 December 2020

Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity.

1 reference

12 December 2020

Studies, using in vivo microdialysis, on the effect of the dopamine uptake inhibitor GBR 12909 on 3,4-methylenedioxymethamphetamine ('ecstasy')-induced dopamine release and free radical formation in the mouse striatum

1 reference

12 December 2020

High‐dose fenfluramine administration decreases serotonin transporter binding, but not serotonin transporter protein levels, in rat forebrain

1 reference

12 December 2020

A study of the mechanisms involved in the neurotoxic action of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') on dopamine neurones in mouse brain

1 reference

12 December 2020

Serotonin syndrome: a brief review

1 reference

12 December 2020

Mechanisms of regrowth of the bulbospinal serotonin system following 5,6-dihydroxytryptamine induced axotomy. I. Biochemical correlates

1 reference

12 December 2020

Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-Hydroxydopamine

1 reference

12 December 2020

Oxidation of vitamin E and vitamin C and inhibition of brain mitochondrial oxidative phosphorylation by peroxynitrite

1 reference

12 December 2020

5,6-Dihydroxytryptamine, a serotonergic neurotoxin, is formed endogenously in the rat brain

1 reference

12 December 2020

Thioether metabolites of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine inhibit human serotonin transporter (hSERT) function and simultaneously stimulate dopamine uptake into hSERT-expressing SK-N-MC cells

1 reference

12 December 2020

Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin

1 reference

12 December 2020

Oxidation of methamphetamine and methylenedioxymethamphetamine by CYP2D6.

1 reference

12 December 2020

Glutathione and N-acetylcysteine conjugates of alpha-methyldopamine produce serotonergic neurotoxicity: possible role in methylenedioxyamphetamine-mediated neurotoxicity

1 reference

12 December 2020

3,4-methylenedioxymethamphetamine (MDMA) administration to rats decreases brain tissue serotonin but not serotonin transporter protein and glial fibrillary acidic protein

1 reference

12 December 2020

Time-course of methamphetamine-induced neurotoxicity in rat caudate-putamen after single-dose treatment

1 reference

12 December 2020

The role of metabolism in 3,4-(+)-methylenedioxyamphetamine and 3,4-(+)-methylenedioxymethamphetamine (ecstasy) toxicity

1 reference

12 December 2020

Neurotoxicity of hydroxylated tryptamines: structure-activity relationships. 1. Long-term effects on monoamine content and fluorescence morphology of central monoamine neurons

1 reference

12 December 2020

A voxel-based PET investigation of the long-term effects of "Ecstasy" consumption on brain serotonin transporters.

1 reference

12 December 2020

Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease

1 reference

12 December 2020

Elevated environmental temperatures can induce hyperthermia during d-fenfluramine exposure and enhance 5-hydroxytryptamine (5-HT) depletion in the brain.

1 reference

12 December 2020

Methamphetamine activates DNA binding of specific redox-responsive transcription factors in mouse brain

1 reference

12 December 2020

3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites

1 reference

12 December 2020

Fenfluramine and norfenfluramine levels in brain microdialysate, brain tissue and plasma of rats administered doses of d-fenfluramine known to deplete 5-hydroxytryptamine levels in brain.

1 reference

12 December 2020

Methamphetamine-induced neurotoxicity in mouse brain is attenuated by ketoprofen, a non-steroidal anti-inflammatory drug

1 reference

12 December 2020

Metabolism is required for the expression of ecstasy-induced cardiotoxicity in vitro

1 reference

12 December 2020

The role of temperature, stress, and other factors in the neurotoxicity of the substituted amphetamines 3,4-methylenedioxymethamphetamine and fenfluramine

1 reference

12 December 2020

Role of quinones in toxicology.

1 reference

12 December 2020

Toxicokinetics of amphetamines: metabolism and toxicokinetic data of designer drugs, amphetamine, methamphetamine, and their N-alkyl derivatives

1 reference

12 December 2020

Immunohistochemical study of short- and long-term effects of DL-fenfluramine on the serotonergic innervation of the rat hippocampal formation

1 reference

12 December 2020

Effects of repeated systemic administration of d-Fenfluramine on serotonin and glutamate release in rat ventral hippocampus: comparison with methamphetamine using in vivo microdialysis

1 reference

12 December 2020

Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity.

1 reference

12 December 2020

Brain hyperthermia induced by MDMA (ecstasy): modulation by environmental conditions

1 reference

12 December 2020

Long-lasting selective depletion of brain serotonin by 5,6-dihydroxytryptamine

1 reference

12 December 2020

Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein

1 reference

12 December 2020

Plasma levels of parent compound and metabolites after doses of either d-fenfluramine or d-3,4-methylenedioxymethamphetamine (MDMA) that produce long-term serotonergic alterations

1 reference

12 December 2020

The NMDA receptor antagonist MK-801 does not protect against serotonin depletions caused by high doses of DL-fenfluramine

1 reference

12 December 2020

Potentiation of NMDA and AMPA responses by the specific mGluR5 agonist CHPG in spinal cord motoneurons

1 reference

12 December 2020

Distinct gene expression signatures in the striata of wild-type and heterozygous c-fos knockout mice following methamphetamine administration: evidence from cDNA array analyses

1 reference

12 December 2020

Serotonin syndrome: not a benign toxidrome

1 reference

12 December 2020

The toxicity of N-methyl-alpha-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine

1 reference

12 December 2020

Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotective

1 reference

12 December 2020

Endogenously produced 5,6-dihydroxytryptamine may mediate the neurotoxic effects of para-chloroamphetamine

1 reference

12 December 2020

In vivo evidence for free radical involvement in the degeneration of rat brain 5‐HT following administration of MDMA (‘ecstasy’) and p‐chloroamphetamine but not the degeneration following fenfluramine

1 reference

12 December 2020