Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis (Q35764554)

10 August 2017

title

Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis (English)

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10 August 2017

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10 August 2017

John P A Ioannidis

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André Uitterlinden

object named as

André G Uitterlinden

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Serena Scollen

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Susana Balcells

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Xavier Nogues

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David Karasik

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Wim Van Hul

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Douglas P Kiel

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Jonathan Reeve

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Claes Ohlsson

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Göran Hallmans

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10 August 2017

Dan Mellström

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10 August 2017

Magnus K Karlsson

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Mattias Lorentzon

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Albert Hofman

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Kim Brixen

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Natasja M van Schoor

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Joyce B J van Meurs

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Leif Mosekilde

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Paul Lips

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Maria Luisa Brandi

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Thomas A Trikalinos

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Kristina Akesson

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Lise Bjerre Husted

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Laura Masi

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Stuart H Ralston

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Bente L Langdahl

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Stephen Kaptoge

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Marcin Kruk

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Roman Lorenc

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Barbara Obermayer-Pietsch

10 August 2017

object named as

Barbara Obermayer-Pietsch

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Huibert A P Pols

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Serge L Ferrari

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Wilfried Renner

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Osten Ljunggren

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Ulrika Pettersson

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David M Reid

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Francois Rousseau

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Lidia Agueda

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Lidia I Benevolenskaya

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Fiona E A McGuigan

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10 August 2017

Kurt Weber

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10 August 2017

GENOMOS Study

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10 August 2017

language of work or name

English

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publication date

1 March 2008

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The Journal of the American Medical Association

10 August 2017

published in

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10 August 2017

volume

299

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10 August 2017

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10 August 2017

page(s)

1277-1290

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Genome-wide significance for dense SNP and resequencing data

10 August 2017

cites work

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Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with peak bone mass in non-sedentary men: results from the Odense androgen study.

2 October 2017

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2 October 2017

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The effect of LRP5 polymorphisms on bone mineral density is apparent in childhood.

2 October 2017

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2 October 2017

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The A1330V polymorphism of the low-density lipoprotein receptor-related protein 5 gene (LRP5) associates with low peak bone mass in young healthy men.

2 October 2017

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Genetic variation at the low-density lipoprotein receptor-related protein 5 (LRP5) locus modulates Wnt signaling and the relationship of physical activity with bone mineral density in men

2 October 2017

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2 October 2017

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2 October 2017

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Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study

2 October 2017

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Pathogenic mutations and polymorphisms in the lipoprotein receptor-related protein 5 reveal a new biological pathway for the control of bone mass

2 October 2017

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Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6

2 October 2017

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Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis

2 October 2017

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Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with variation in vertebral bone mass, vertebral bone size, and stature in whites

2 October 2017

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Measuring inconsistency in meta-analyses

2 October 2017

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High bone mass in mice expressing a mutant LRP5 gene

2 October 2017

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Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density

2 October 2017

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Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

2 October 2017

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2 October 2017

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High bone density due to a mutation in LDL-receptor-related protein 5

2 October 2017

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A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait

2 October 2017

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2 October 2017

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A New Statistical Method for Haplotype Reconstruction from Population Data

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Large-scale association study between two coding LRP5 gene polymorphisms and bone phenotypes and fractures in men

12 July 2018

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Low-density lipoprotein receptor-related protein 5 (LRP5) gene polymorphisms are associated with bone mass in both Chinese and whites.

25 September 2018

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Q89R polymorphism in the LDL receptor-related protein 5 gene is associated with spinal osteoarthritis in postmenopausal Japanese women.

25 September 2018

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Molecularly-defined lactose malabsorption, milk consumption and anthropometric differences in adult males

25 September 2018

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MTHFR c.677C>T polymorphism as an independent predictor of peak bone mass in Danish men--results from the Odense Androgen Study

25 September 2018

1 reference

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Association of polymorphisms in low-density lipoprotein receptor-related protein 5 gene with bone mineral density in postmenopausal Chinese women.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282142

Free testosterone is a positive, whereas free estradiol is a negative, predictor of cortical bone size in young Swedish men: the GOOD study

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3282142

Loci for regulation of bone mineral density in men and women identified by genome wide linkage scan: the FAMOS study.

25 September 2018

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Association of a single-nucleotide polymorphism in low-density lipoprotein receptor-related protein 5 gene with bone mineral density

25 September 2018

1 reference

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25 September 2018

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Polymorphisms in the osteoprotegerin gene are associated with osteoporotic fractures

25 September 2018

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Attrition in the Longitudinal Aging Study Amsterdam. The effect of differential inclusion in side studies.

25 September 2018

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25 September 2018

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Polymorphism of the Aromatase Gene in Postmenopausal Italian Women: Distribution and Correlation with Bone Mass and Fracture Risk1

25 September 2018

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25 September 2018

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COL1A1, ESR1, VDR and TGFB1 polymorphisms and haplotypes in relation to BMD in Spanish postmenopausal women

25 September 2018

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Differential Genetic Effects of ESR1 Gene Polymorphisms on Osteoporosis Outcomes

15 November 2018

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Common Genetic Variation of the Low-Density Lipoprotein Receptor-Related Protein 5 and 6 Genes Determines Fracture Risk in Elderly White Men

15 November 2018

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Influence of LRP5 Polymorphisms on Normal Variation in BMD

15 November 2018

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Large-scale population-based study shows no association between common polymorphisms of the TGFB1 gene and BMD in women

15 November 2018

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12 December 2020

Association of a single-nucleotide variation (A1330V) in the low-density lipoprotein receptor-related protein 5 gene (LRP5) with bone mineral density in adult Japanese women

1 reference

12 December 2020

LRP5 coding polymorphisms influence the variation of peak bone mass in a normal population of French-Canadian women

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12 December 2020

The assessment of vertebral deformity: a method for use in population studies and clinical trials

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12 December 2020

Long-term fracture prediction by bone mineral assessed at different skeletal sites

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12 December 2020

Contribution of the LRP5 gene to normal variation in peak BMD in women

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12 December 2020

LRP5 gene polymorphisms predict bone mass and incident fractures in elderly Australian women

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12 December 2020

Type 2 diabetes mellitus in nursing home patients: effects on bone turnover, bone mass, and fracture risk

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12 December 2020

Identifiers

DOI

10.1001/JAMA.299.11.1277

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10 August 2017

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10 August 2017

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