Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast (Q35763361)

10 August 2017

title

Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast (English)

1 reference

10 August 2017

0 references

Susan Lindquist

1 reference

10 August 2017

David A Bennett

1 reference

10 August 2017

Eric M Reiman

1 reference

10 August 2017

Rudolph E Tanzi

1 reference

10 August 2017

Denis A Evans

1 reference

10 August 2017

Sebastian Treusch

1 reference

10 August 2017

Shusei Hamamichi

1 reference

10 August 2017

Jessica L Goodman

1 reference

10 August 2017

Kent E S Matlack

1 reference

10 August 2017

Chee Yeun Chung

1 reference

10 August 2017

Valeriya Baru

1 reference

10 August 2017

Joshua M Shulman

1 reference

10 August 2017

Antonio Parrado

1 reference

10 August 2017

Brooke J Bevis

1 reference

10 August 2017

Julie S Valastyan

1 reference

10 August 2017

Haesun Han

1 reference

10 August 2017

Malin Lindhagen-Persson

1 reference

10 August 2017

Anders Olofsson

1 reference

10 August 2017

Philip L DeJager

1 reference

10 August 2017

Kim A Caldwell

1 reference

10 August 2017

Guy A Caldwell

1 reference

10 August 2017

language of work or name

English

0 references

publication date

27 October 2011

1 reference

10 August 2017

1 reference

10 August 2017

volume

334

1 reference

10 August 2017

issue

6060

1 reference

10 August 2017

page(s)

1241-1245

1 reference

Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons

10 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Soluble oligomers of amyloid-β peptide disrupt membrane trafficking of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor contributing to early synapse dysfunction.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Amyloid-β Oligomer Specificity Mediated by the IgM Isotype – Implications for a Specific Protective Mechanism Exerted by Endogenous Auto-Antibodies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

α-Synuclein impairs macroautophagy: implications for Parkinson's disease.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Pathways linking Abeta and tau pathologies.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Intermediate phenotypes identify divergent pathways to Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Alpha-synuclein delays endoplasmic reticulum (ER)-to-Golgi transport in mammalian cells by antagonizing ER/Golgi SNAREs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Amyloid precursor protein trafficking, processing, and function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Interaction between Epsin/Yap180 adaptors and the scaffolds Ede1/Pan1 is required for endocytosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Presenilin: running with scissors in the membrane

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Structure and function analysis of the CMS/CIN85 protein family identifies actin-bundling properties and heterotypic-complex formation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Clathrin-mediated endocytosis at synapses

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

PtdIns(4,5)P2 turnover is required for multiple stages during clathrin- and actin-dependent endocytic internalization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Intracellular Abeta and cognitive deficits precede beta-amyloid deposition in transgenic arcAbeta mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

The Rsp5 ubiquitin ligase binds to and ubiquitinates members of the yeast CIN85-endophilin complex, Sla1-Rvs167.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Secretion efficiency in Saccharomyces cerevisiae of bovine pancreatic trypsin inhibitor mutants lacking disulfide bonds is correlated with thermodynamic stability

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Identification and characterization of a nerve terminal-enriched amphiphysin isoform

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Control of protein exit from the endoplasmic reticulum

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Yeast cells provide insight into alpha-synuclein biology and pathobiology

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

CEP-1347/KT-7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Abeta-induced cortical neuron apoptosis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281757

Genome-wide analysis of genetic loci associated with Alzheimer disease

25 September 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213210

A suite of Gateway cloning vectors for high-throughput genetic analysis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213210

An improved system for estradiol-dependent regulation of gene expression in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213210

Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213210

C. elegans ORFeome version 3.1: increasing the coverage of ORFeome resources with improved gene predictions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213210

hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213210

Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213210

Long-term culture of mouse cortical neurons as a model for neuronal development, aging, and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213210

CR1 is associated with amyloid plaque burden and age-related cognitive decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213210

A second generation human haplotype map of over 3.1 million SNPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213210

A mitocentric view of Alzheimer's disease suggests multi-faceted treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213210

Role of mitochondrial amyloid-beta in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1213210

Modelling neurodegeneration in Saccharomyces cerevisiae: why cook with baker's yeast?

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22033521

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22033521

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1213210

1 reference

10 August 2017

1 reference

10 August 2017

1 reference